All Cancer Microbiology articles – Page 4
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NewsGut bacteria may tip the balance between feeding tumors and fueling immunity
A new study reveals how bacteria in the gut can help determine whether the amino acid asparagine from the diet will feed tumor growth or activate immune cells against the cancer.
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NewsFecal microbiota transplantation improves response to immunotherapy in advanced kidney cancer
A new study provides compelling evidence that fecal microbiota transplantation (FMT) can enhance the effectiveness of immunotherapy in patients with advanced metastatic renal cell carcinoma (mRCC).
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NewsInnovative ‘poop pills’ show promising results in clinical trials for multiple types of cancer
Fecal microbiota transplants (FMT), can dramatically improve cancer treatment. One study shows that the toxic side effects of drugs to treat kidney cancer could be eliminated with FMT. A second suggests FMT is effective in improving the response to immunotherapy in patients with lung cancer and melanoma.
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NewsMore investigations needed into Wumei Pills-Lactobacillus Reuteri-intestinal stem cell axis for chemotherapy-Induced mucositis
A new letter appraising a recent study suggests the reported benefits of WMP and Lactobacillus reuteri in chemotherapy-induced mucositis are promising, but stronger causal and analytical foundations are needed.
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NewsScientists synthesize medicarpin in baker’s yeast
Scientists have developed a way to synthesize medicarpin in yeast. Like palitaxel in the 1990s, this tumor-attacking sustance has only limited natural quantitites and is considered difficult to synthesize.
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NewsChemotherapy rewires gut bacteria to curb metastasis
Researchers report that chemotherapy-induced damage to the intestinal lining alters nutrient availability for gut bacteria, reshaping the microbiota and increasing the production of indole-3-propionic acid (IPA), a tryptophan-derived microbial metabolite.
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NewsOral bacterium may promote breast cancer development and spread
Researchers found that Fusobacterium nucleatum, an oral bacterium commonly associated with periodontal disease, can promote breast cancer initiation, tumor growth and spread by inducing DNA damage and altering cancer cell behavior.
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NewsExperts propose fibre as first new essential nutrient in 50 years - as gut microbiome research gathers pace
Nutrition experts are calling for dietary fibre to be officially recognised internationally as an essential nutrient - the first ‘new’ essential nutrient in more than 50 years. They point out that the gut microbiome exists almost exclusively on the dietary fibre we eat.
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NewsEngineered yeast delivers record levels of animal-free chondroitin sulfate
A new study establishes a robust yeast-based platform that overcomes the long-standing trade-off between yield and sulfation, enabling sustainable, high-level production of high-quality chondroitin sulfate without reliance on animal sources.
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NewsEngineering yeast to make rare anticancer saponins: reconstructing the complete biosynthesis of polyphyllin II
By combining plant transcriptomics, enzyme engineering, and synthetic biology, a new study demonstrates, for the first time, the full heterologous production of polyphyllin II in Saccharomyces cerevisiae.
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NewsA bacterial toxin can counteract colorectal cancer growth
A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. Systemic administration of the purified bacterial substance changes the immune microenvironment in tumours.
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NewsGut bacteria molecule boosts lung cancer treatment response
Researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.
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NewsScientists observe infections by cancer-causing retroviruses in koalas as they occur
Scientists analysed the ongoing colonization by two retroviruses of the germline of koalas and resulting deaths from cancer in multi-generational pedigrees of over 100 koalas in US and European zoos. They calculated genetic risk scores (GRS) that can help guide koala breeding programs.
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NewsNew hypothesis links HPV E6 and SARS‑CoV‑2 spike proteins to reduced p53 activity
Scientists have proposed a hypothesis suggesting that virally encoded proteins such as HPV-E6 or SARS-COV-2 Spike may cooperate in suppressing host defenses including tumor suppressor mechanisms involving p53.
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NewsInjectable hydrogel-mediated co-delivery of oncolytic adenovirus and melphalan for retinoblastoma control and vision preservation
The collagen-based hydrogel enabled controlled oncolytic adenovirus and melphalan release and sustained retention. This approach eradicated retinoblastoma tumors and restored normal ocular structure and visual function following intravitreal administration.
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NewsVictoria’s Secret grant backs cutting-edge ovarian cancer research
Promising ovarian cancer research by Melanie Rutkowski, PhD, at the University of Virginia Comprehensive Cancer Center has won $700,000 in support from the Victoria’s Secret Global Fund for Women’s Cancers in partnership with Pelotonia and AACR, the American Association for Cancer Research.
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NewsNew research decodes the bacterial “zip code” of colorectal cancer for prediction and survival
A recent study shows that bacteria living inside colorectal tumors form distinct ecosystems that are closely linked to how the disease progression and patient outcomes.
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NewsNew evidence reveals Streptococcus anginosus drives gastric cancer development
A recent study has revealed a novel cancer-promoting mechanism of Streptococcus anginosus. The research shows that methionine metabolites produced by this bacterium can significantly contribute to the development of gastric cancer.
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NewsResearch links tumor bacteria to immunotherapy resistance in head and neck cancer
Two new studies reveal that elevated levels of bacteria in the tumor microenvironment suppress immune response, driving resistance to immunotherapy in patients with head and neck squamous cell carcinoma.
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NewsClostridioides difficile: A suspected pro-carcinogenic bacterium for gastrointestinal tumors
A new review proposes that C. difficile infection (CDI) may be a previously underappreciated pro-carcinogenic factor in CRC and possibly other gastrointestinal cancers, offering a fresh angle for research and prevention strategies.