All Cancer Microbiology articles – Page 2
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NewsSleep deprivation disrupts gut microbiota, worsening colorectal cancer outcomes
Researchers have found that the gut microbiota drives changes to the immune system caused by chronic sleep loss. These changes promote cancer progression, disrupt circadian rhythm and weaken the effectiveness of chemotherapy.
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NewsThree European countries reach 90% HPV vaccination target as Europe steps up action on cancer prevention
All EU/EEA countries now recommend HPV vaccination for adolescent girls and boys as part of their immunisation programmes, marking a major step forward in Europe’s’ cancer prevention efforts. Iceland, Portugal and Norway have reached the target of 90% HPV vaccination coverage among girls by the age of 15.
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NewsStudy reveals genome-wide host–virus genetic interactions in cancer risk
Researchers report a major advance in understanding how interactions between human and viral genomes shape disease risk. They found that variations in the Epstein–Barr virus, together with a specific immune-related gene (HLA-A*11:01), strongly influence the risk of nasopharyngeal cancer.
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NewsCat viruses offer window into human oncogenesis
Cats are not just beloved companions; they are emerging as key “research partners” in unravelling viral cancer mechanisms. A new review explores how feline tumour viruses offer vital insights into human oncology and viral carcinogenesis from a comparative oncology perspective.
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NewsMethod for amplifying the full genome of human papillomavirus 16 uses overlapping extension polymerase chain reaction
Human papillomavirus (HPV) is a double-stranded circular DNA virus with a genome of approximately 7–8 kb. A new study aims to establish an overlapping extension polymerase chain reaction method for the amplification of the entire genome of HPV16.
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NewsImmunogenicity and safety of an Escherichia coli-produced 9-valent HPV vaccine in adolescents compared with young women
Based on new findings, the National Medical Products Administration of China has approved a two-dose immunization schedule for the domestically produced 9-valent HPV vaccine in girls aged 9 to 17 years.
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NewsResearchers to test a gut microbiome intervention as part of a cancer therapy regimen
A phase III clinical trial will test a gut microbiome intervention as part of a kidney cancer therapy regimen. The investigational agent is a once-daily capsule requiring no refrigeration or special handling.
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NewsTurmeric/ginger extract shows multiple benefits for bone implants
An extract of turmeric and ginger helps bone implants bond strongly while killing bacteria and cancer cells, according to new research with implications for millions of patients with joint replacements and bone cancer.
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NewsA new mouse model of virus-driven liver cancer may open the door to better diagnosis and treatments
Researchers have created the first mouse model in which chronic viral infection progresses to liver cancer, closely mirroring what happens in people with hepatitis C.
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NewsShiitake-derived β-glucan inhibits human cervical cancer progression through DMBT1
A team of researchers investigated the molecular mechanism underlying the anti-cervical cancer activity of Lentinus edodes-derived β-glucan (LNT) and, for the first time, identified DMBT1 as a key target.
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NewsVirus-inspired DNA needle could pave the way for better medicines
Researchers have developed a microscopic DNA needle that delivers molecules directly into cells and helps keep them active. It may solve a major problem in modern medicine: many therapies are trapped inside cells and lose their effect.
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NewsThe tumor microbiota: A new frontier in cancer biology
A new study synthesizes evidence from different types of tumors, particularly those characterized by low microbial biomass, where conclusions require particularly rigorous validation. By outlining a roadmap of experimental and analytical standards, this work provides the basis for more robust research.
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NewsHKU innovations achieve recognition at the 51st International Exhibition of Inventions at Geneva
The University of Hong Kong (HKU) secured 46 awards at the 51st International Exhibition of Inventions of Geneva, including recognition for a project aiming to gain immunity against the three major respiratory viruses through home-based toothbrushing.
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NewsTarget behind cancer drug shown to help fight influenza in mice
A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza. A study found that Programmed Death-Ligand 1 (PD-L1), best known for helping tumors evade immune attack, instead helped immunocompromised mice clear flu-infected lung cells and survive infection.
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NewsNew drug candidate extremely effective against H. pylori bacterium
Researchers have discovered that metronidazole targets two central protective proteins of Helicobacter pylori: an enzyme responsible for detoxifying harmful reactive oxygen species and a protein that repairs damaged proteins.
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NewsScientists uncover how HPV-positive cancers hide from the immune system — and how to make them visible again
A new study solves a major mystery in cancer immunology by uncovering how HPV hides cancer cells from the immune system by using MARCHF8 to destroy MHC-I, which serves as a warning flag for the immune system.
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NewsEngineered bacteria deliver cancer drug directly inside tumors in mice
New research suggests that Escherichia coli Nissle 1917 (EcN) may be engineered with anticancer agents to treat cancerous tumors in mice. Researchers used EcN as a base for synthesizing Romidepsin (FK228), an FDA-approved drug with anti-tumor agents.
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NewsSevere COVID-19 and flu facilitate lung cancer months or years later, new research shows
Severe COVID-19 and influenza infections prime the lungs for cancer and can accelerate the disease’s development, but vaccination heads off those harmful effects, new research indicates.
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News‘Bugs delivering drugs’ – new approach to colorectal cancer treatment using common food-borne bacteria
Researchers have published a novel approach to fight colorectal cancer, using modified bacteria as a courier to deliver potent cancer-killing proteins into tumor cells.
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NewsStudy highlights gut–brain axis in pituitary tumor–related cognitive decline
Researchers conducted a prospective cross-sectional study to evaluate cognitive function in patients with pituitary neuroendocrine tumors and examine associations among tumor lineage, hormonal abnormalities, and gut microbiota composition.