All Cancer Microbiology articles – Page 2
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NewsExperts propose fibre as first new essential nutrient in 50 years - as gut microbiome research gathers pace
Nutrition experts are calling for dietary fibre to be officially recognised internationally as an essential nutrient - the first ‘new’ essential nutrient in more than 50 years. They point out that the gut microbiome exists almost exclusively on the dietary fibre we eat.
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NewsEngineered yeast delivers record levels of animal-free chondroitin sulfate
A new study establishes a robust yeast-based platform that overcomes the long-standing trade-off between yield and sulfation, enabling sustainable, high-level production of high-quality chondroitin sulfate without reliance on animal sources.
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NewsEngineering yeast to make rare anticancer saponins: reconstructing the complete biosynthesis of polyphyllin II
By combining plant transcriptomics, enzyme engineering, and synthetic biology, a new study demonstrates, for the first time, the full heterologous production of polyphyllin II in Saccharomyces cerevisiae.
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NewsA bacterial toxin can counteract colorectal cancer growth
A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. Systemic administration of the purified bacterial substance changes the immune microenvironment in tumours.
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NewsGut bacteria molecule boosts lung cancer treatment response
Researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.
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NewsScientists observe infections by cancer-causing retroviruses in koalas as they occur
Scientists analysed the ongoing colonization by two retroviruses of the germline of koalas and resulting deaths from cancer in multi-generational pedigrees of over 100 koalas in US and European zoos. They calculated genetic risk scores (GRS) that can help guide koala breeding programs.
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NewsNew hypothesis links HPV E6 and SARS‑CoV‑2 spike proteins to reduced p53 activity
Scientists have proposed a hypothesis suggesting that virally encoded proteins such as HPV-E6 or SARS-COV-2 Spike may cooperate in suppressing host defenses including tumor suppressor mechanisms involving p53.
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NewsInjectable hydrogel-mediated co-delivery of oncolytic adenovirus and melphalan for retinoblastoma control and vision preservation
The collagen-based hydrogel enabled controlled oncolytic adenovirus and melphalan release and sustained retention. This approach eradicated retinoblastoma tumors and restored normal ocular structure and visual function following intravitreal administration.
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NewsVictoria’s Secret grant backs cutting-edge ovarian cancer research
Promising ovarian cancer research by Melanie Rutkowski, PhD, at the University of Virginia Comprehensive Cancer Center has won $700,000 in support from the Victoria’s Secret Global Fund for Women’s Cancers in partnership with Pelotonia and AACR, the American Association for Cancer Research.
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NewsNew research decodes the bacterial “zip code” of colorectal cancer for prediction and survival
A recent study shows that bacteria living inside colorectal tumors form distinct ecosystems that are closely linked to how the disease progression and patient outcomes.
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NewsNew evidence reveals Streptococcus anginosus drives gastric cancer development
A recent study has revealed a novel cancer-promoting mechanism of Streptococcus anginosus. The research shows that methionine metabolites produced by this bacterium can significantly contribute to the development of gastric cancer.
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NewsResearch links tumor bacteria to immunotherapy resistance in head and neck cancer
Two new studies reveal that elevated levels of bacteria in the tumor microenvironment suppress immune response, driving resistance to immunotherapy in patients with head and neck squamous cell carcinoma.
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NewsClostridioides difficile: A suspected pro-carcinogenic bacterium for gastrointestinal tumors
A new review proposes that C. difficile infection (CDI) may be a previously underappreciated pro-carcinogenic factor in CRC and possibly other gastrointestinal cancers, offering a fresh angle for research and prevention strategies.
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NewsCancer-fighting bacterial product ‘cocktails’ may offer personalized treatment
Bacteria may be the next frontier in cancer treatment, according to researchers who devised a new approach of creating bacteria-derived mixtures — or cocktails — to help fight bladder cancer. They found that the cocktails significantly boost the immune system’s ability to fight cancer.
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NewsGut bacteria from amphibians and reptiles achieve complete tumor elimination
Researchers have discovered that the bacterium Ewingella americana, isolated from the intestines of Japanese tree frogs (Dryophytes japonicus), possesses remarkably potent anticancer activity.
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NewsResearchers see dramatic drop in HIV-infected immune cells in patient after cancer treatment received
Researchers report they may have taken an early step toward a more practical HIV cure. They focused on a patient undergoing cancer treatment and also living with HIV, who after receiving chemotherapy, had a significant reduction in the number of CD4+ T immune cells that contained an HIV provirus.
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NewsEngineering oncolytic bacteria as precision cancer therapeutics
A new review summarizes recent advances in the design and application of synthetic biological strategies that enhance bacterial precision, safety, and efficacy in tumor therapy.
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NewsGlobal Virus Network announces appointment of new board members
The Global Virus Network (GVN), a worldwide coalition of leading human and animal virologists, has announced the appointment of eight distinguished leaders to its Board of Directors.
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NewsEngineered virus boosts immune response against glioblastoma in preclinical models
Researchers have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells. A single dose of the modified virus increased T-cell, natural killer cell, and myeloid cell responses in the tumor microenvironment and increased the overall survival in preclinical models.
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NewsChemists synthesize a fungal compound that holds promise for treating brain cancer
For the first time, chemists have synthesized a fungal compound known as verticillin A, which was discovered more than 50 years ago and has shown potential as an anticancer agent.