All Cancer Microbiology articles
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NewsEngineered bacterial therapy activates immune response in cancer preclinical studies
Researchers have developed a new bacterial immunotherapy that delivers immune-activating proteins directly to solid tumors, which can often suppress the immune system. ACTM-838 targets phagocytic immune cells within the tumor microenvironment.
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NewsChanges in gut microbiota influence which patients get AIG-related neuroendocrine tumors
Researchers have discovered how the balance of bacteria in the stomach affects the growth of neuroendocrine tumors (NETs). By identifying the specific bacteria involved and the biochemical reactions that cause tumor growth, they hope to detect which patients are most likely to develop cancer.
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NewsMicroplastics found to change gut microbiome in first human-sample study
New research presented today at UEG Week 2025 shows that microplastics can alter the human gut microbiome, with some changes resembling patterns linked to depression and colorectal cancer.
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NewsGenetic ‘Trojan horse’ selectively kills cancer cells linked to Kaposi’s sarcoma
A highly targeted gene therapy that could revolutionize treatment for cancers linked to a common herpesvirus harnesses an adeno-associated virus (AAV) to deliver a genetic “Trojan horse” into infected cells.
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NewsNew herpes virus–based vaccine could cure cancer in the future without side effects
The Herpes simplex virus is a widespread virus that often causes cold sores, and most people carry it. By removing a virulence gene, i.e. a gene that makes the virus harmful to humans, the herpes virus can be repurposed as a cancer vaccine.
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NewsNew one-hour, low-cost HPV test could transform cervical cancer screening in Africa and beyond
A team of researchers has developed a simple, affordable human papillomavirus (HPV) test that delivers results in less than an hour with no specialized laboratory required.
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NewsStudy shows HPV vaccine protects vaccinated — and unvaccinated — women
A study has found that the introduction of the human papillomavirus (HPV) vaccine in community settings is highly effective in protecting young women from infections caused by the cervical-cancer-causing virus—including women who didn’t even receive the vaccine.
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NewsNew study supports gene-tailored radiation doses to treat HPV+ throat cancer
Genetic testing can identify patients with HPV-positive throat cancer who may benefit from lower radiation doses, according to a new study that builds on a growing body of evidence that radiation treatment can be personalized using tumor genomics.
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NewsFatty acids feed cancer-promoting bacteria: How chronic cellular stress alters the gut microbiome
Researchers have identified a cellular mechanism that alters the gut microbiome in a way that promotes cancer. An analysis of patient data shows that the findings also apply to humans.
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NewsEngineered gut bacteria improves survival outcomes in colorectal cancer tumors
A genetically modified Salmonella typhimurium strain can colonise tumours and release a therapeutic protein, LIGHT, to induce the formation of mature tertiary lymphoid structures (mTLSs) in laboratory models.
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NewsMolecular roadmap links stomach infection to cancer risk
A new study has identified protein signatures that trace the trajectory from Helicobacter pylori infection to the progression of gastric lesions and eventual cancer. Researchers pinpointed 28 proteins that change consistently during this process.
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NewsResearch breakthrough offers hope for new colorectal cancer treatments
Researchers have identified the key mechanism by which Fusobacterium nucleatum binds to the human cell receptors CEACAM1 and CEACAM5, which are frequently overexpressed on many types of cancer cells.
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NewsOral microbes linked to increased risk of pancreatic cancer
Twenty-seven species of bacteria and fungi among the hundreds that live in people’s mouths have been collectively tied to a 3.5 times greater risk of developing pancreatic cancer, a study shows.
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NewsBlood microbial DNA distinguishes liver cancer from metastatic lesions
A simple blood test analyzing microbial DNA could help doctors tell apart primary liver cancer from colorectal cancer that has spread to the liver, according to a new study.
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NewsHPV integration: Moving from carcinogenesis mechanisms to clinical applications
The clinical significance of HPV integration into the host genome is substantial, particularly in cervical cancer screening programs. Integration testing has emerged as a valuable triage tool for detecting high-grade cervical intraepithelial neoplasia (CIN III+).
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NewsTargeted delivery of microRNA sponge short-hairpin RNA via VIR-inspired biotechnical vector
The Vir-inspired Biotechnical Vector (VIBV) is a novel hybrid platform that combines viral and non-viral elements with nanotechnology to enable personalized, tumor-specific gene therapy.
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NewsMicrobiotica announces completion of recruitment in its international phase 1b trial of microbiome co-therapy
Microbiotica, a clinical-stage biopharma company developing a pipeline of oral precision microbiome medicines called live biotherapeutic products (LBPs), announces that patient recruitment is complete in its advanced melanoma (MELODY-1) trial.
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NewsBout of cystitis may signal presence of urogenital cancers in middle-aged adults
A bout of the common bladder infection, cystitis, may signal the presence of urogenital cancers—which affect parts of the body involved in reproduction and excretion—in middle aged adults, suggests research. The risks seem to be especially high within 3 months of infection.
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NewsMicrobial allies: Bacteria help fight against cancer
An international team of scientists have discovered that microbes associated with tumours produce a molecule that can control cancer progression and boost the effectiveness of chemotherapy.
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NewsResearchers uncover how COVID-19 may linger in cancer patients and affect treatment outcomes
New research is providing important insights into how COVID-19 persists in cancer patients even long after testing positive. Researchers studied three cancer patients who had undergone transplant therapies and were hospitalized with severe COVID-19 infections.