All Crohn’s disease articles
-
NewsChildren with Crohn’s have distinct gut bacteria from kids with other digestive disorders
Researchers have found a “microbial signature” of pediatric Crohn’s disease that differs from the makeup of gut bacteria in children with other gastrointestinal conditions, with Crohn’s patients harboring more pro-inflammatory bacteria and less protective bacteria.
-
NewsA simple blood test can predict Crohn’s disease years before symptoms appear
Researchers have shown a blood test can predict Crohn’s disease years before symptoms appear, opening the doors to early diagnosis and potentially prevention. The test measures a person’s immune response to flagellin, a protein found on gut bacteria.
-
NewsGut bacteria changes at the earliest stages of inflammatory bowel disease
People newly diagnosed with the most common IBD subtypes, Crohn’s disease and ulcerative colitis, lose beneficial anaerobic bacteria that help with digestion of complex carbohydrates. Patients instead experience a rise in oxygen-tolerant bacteria from the mouth that travel in the gut.
-
NewsToxic gut bacteria may drive ulcerative colitis by killing protective immune cells
A toxin-secreting gut bacterium may fuel ulcerative colitis by killing protective immune cells that maintain intestinal homeostasis, according to a new study. The findings suggest potential for new treatment strategies.
-
NewsThe fart factor: researchers get wind of hydrogen’s role in the gut
Scientists have revealed how hydrogen is made and used in the human gut. Though infamous for making farts ignite, hydrogen also has a positive role supporting gut health.
-
NewsRebalancing the gut: how AI solved a 25-year Crohn’s disease mystery
Researchers have settled a decades-long debate surrounding the role of the first Crohn’s disease gene to be associated with a heightened risk for developing the auto-immune condition.
-
NewsA surprising link between Crohn’s disease and the Epstein-Barr virus
A longitudinal study has revealed strong and surprising evidence showing that exposure to Epstein-Barr virus (EBV) can lead to a higher risk of Crohn’s disease. Researchers are now trying to find out the mechanistic actions in their associations.
-
NewsMicrobiome as a potential key to better treatment: Clinical study on new therapy for Crohn’s disease
A joint research project has found that a combination of dietary therapy and fecal microbiome transfer (FMT) greatly alleviate intestinal inflammation in mice. A clinical trial on this new therapeutic approach is under way to potentially treat Crohn’s disease.
-
NewsPossible trigger of Crohn’s disease discovered: Dysfunctional mitochondria disrupt gut microbiome
Disruptions of mitochondrial functions have an influence on Crohn’s disease, a connection now revealed by researchers who showed that defective mitochondria in mice trigger symptoms of chronic intestinal inflammation and influence the microbiome.
-
News$5.6 million grant awarded to target treatments for IBS, Crohn’s and Ulcerative colitis
An “out-of-the-box” study has been awarded a $5.6 million NIH grant to target treatments for IBS, Crohn’s, Ulcerative Colitis and more.
-
NewsStudy reveals possible triggers for inflammatory bowel disease
A new study finds a complex interplay between diet, genes, and the gut microbiota that could explain why IBD develops.
-
NewsNew understanding of the gut immune system may hold promise for Crohn’s disease patients
A team of scientists have uncovered an overlooked mechanism in the gut immune system of patients suffering from severe cases of Crohn’s disease. The discovery may help define how to treat patients with severe Crohn’s disease.
-
NewsDeep dive into the gut unlocks new disease treatments
Researchers say it’s not only possible to map just what species are in the gut microbiome but how they interact and how that can affect the whole body.
-
NewsOral lipid nanoparticle drug can prevent development of colitis-associated cancer
An oral lipid nanoparticle drug prevents tumor development in mice, suggesting this is a promising drug formulation for preventing colitis-associated cancer, according to a study led by researchers in the Institute for Biomedical Sciences at Georgia State University. The findings published in the journal Pharmaceutics report the ...
-
NewsMicrogel treatment helps ‘good’ gut bacteria and clears out the ‘bad’
Researchers have developed a microgel delivery system for probiotics that keeps ‘good’ bacteria safe while actively clearing out ‘bad’ ones.
-
NewsSleep supplement impairs action of gut microbiota
Despite its antioxidant effects and role in regulating sleep cycles, tests show melatonin can worsen inflammation of the intestine and impair the action of gut microbiota.
-
NewsStool transplants more effective than antibiotics for treating recurring, life-threatening gut infections
A new Cochrane Review has found that, compared with standard antibiotic treatment, stool transplantation can increase the number of people recovering from Clostridioides difficile infection from 40% to 77%.
-
NewsProbiotic ‘backpacks’ could treat inflammatory bowel diseases
Researchers have devised specialised nano-particles that can neutralise molecules linked to inflammatory bowel disease (IBD), and can be attached to beneficial probiotic bacteria targeting the gut.