All Disease Pathology articles – Page 3
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NewsDevelopment of dual-action compounds to fight cancer and infections
Researchers have developed new hybrid compounds that simultaneously reduce the viability of aggressive cancer cells and inhibit the growth of certain bacteria and fungi.
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NewsGut-pancreas immune crosstalk may offer new therapeutic strategies for pancreatic cancer
A new study reports that immune responses produced in lymph nodes shared by the liver, pancreas and intestine shape T-cell tolerance. This cross-organ immune rewiring increases T-cell infiltration into pancreatic tumors, pointing to potential new approaches for hard-to-treat pancreatic cancers.
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News‘Known’ TB gene springs to action under stress, with an unexpected biological role
New research has discovered that one of TB’s supposedly “known” genes has a completely unexpected biological role, with far-reaching implications.
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NewsPreventive TB treatment for individuals with HIV shown to be effective in real-world settings
A new study has evaluated the real-world impact of TB preventive treatment in six countries with high TB and HIV rates and highlights the importance of preventive treatment in reducing deaths caused by a curable disease.
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News35-year study reshapes our understanding of Lyme disease ecology
Researchers reveal surprising findings from one of the world’s longest-running ecological monitoring programs tracking ticks and their hosts.
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NewsEngineered macrophages gain enhanced bacteria-targeting ability
A novel membrane interface engineering strategy enables immune cells to specifically recognize, capture and eliminate pathogenic bacteria without genetic modification.
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NewsResearchers identify rapidly spreading genetic variants that make parasites resistant to malaria treatment
New genetics study helps explain declining malaria drug susceptibility and highlights the urgent need to track mutations and improve current therapies.
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NewsCells use a little-known molecule to protect themselves from iron overload
New research shows that cells rely on an unexpected protector against elevated iron levels: small molecules called polyamines. These small molecules act like storage lockers for iron, safely holding the metal in a non-reactive state until cells need it.
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NewsNovel AI model accurately detects key gene mutations and predicts biomarkers across 32 cancer types
Researchers have developed a novel AI model capable of predicting cancer subtypes, specific genetic mutations, and survival outcomes across 32 different cancers.
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NewsImmune molecules play a limited role in ALS progression
New research indicates that immune-related molecules change in motor neurons affected by amyotrophic lateral sclerosis (ALS), but they do not appear to be major drivers of disease progression.
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NewsPregnancy increases immune burden on women with arthritis and lupus
New research finds that the immune system of women with autoimmune diseases such as rheumatoid arthritis and lupus react very differently to pregnancy: rheumatoid arthritis patients often experience an improvement in symptoms, while lupus patients have an elevated risk of deterioration.
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NewsCould preventing shingles also help prevent dementia?
A new study finds that older adults who received a shingles vaccine had a 24% lower risk of developing dementia over four years. The findings add to growing evidence that preventing shingles may also protect against neurological disease.
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NewsWorld’s first oral microbiome-based nanomedicine to supercharge anti-cancer immunity
Researchers have successfully developed the world’s first oral, microbiome-based nanomedicine which enhances the ability of immune cells to attack cancer cells.
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NewsTriple-dose regimen may permanently clear HIV in infected newborns
New research suggests a one-time regimen of therapies given to newborns within three days of birth could permanently clear HIV infection.
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NewsNew viral marker strategies improve prediction of functional cure in chronic hepatitis B
Researchers identify how combining classical and emerging viral biomarkers can better predict functional cure and guide individualized hepatitis B treatment.
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NewsStudy finds HIV-1 proviruses may drive chronic systemic inflammation
People living with HIV are at higher risk of developing inflammatory diseases of many tissues, even when receiving antiviral treatments. A new study suggests that persistent hidden HIV contributes to this inflammation.
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NewsObesity drug significantly reduces the risk of infections and serious cardiovascular events
Tirzepatide, marketed under the brand name Mounjaro, could reduce the risk of heart attacks and hospitalizations due to infections in people with type 2 diabetes by by about one-third when compared with a conventional diabetes medication.
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NewsThe ‘windows’ that set genotoxic bacteria on a track towards colorectal cancer
Scientists have identified potential ‘windows of opportunity’ that can provide routes for some pathogenic strains of E coli to cause mutations that ultimately lead to colorectal cancers.
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NewsResearchers uncover unexpected twist in fight against antibiotic resistance
A group of Cornell College students and their professor have discovered surprising results in their research on antimicrobial peptides, which are being studied as a method of combating antibiotic resistance.
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NewsResearchers develop new drug to attack an enduring killer
Researchers have developed a new antimalarial drug designed to thwart even the most drug-resistant forms of the infection.