All Disease Pathology articles – Page 3
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NewsFirst 24 hours after viral infection are critical
New research suggests that the first 24 hours after viral infection is critical in determining infection severity.
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NewsNew discovery could help scientists fight deadly fungal infections
Researchers have discovered that the bacterial antibiotic ‘gladiolin’ can disarm Candida albicans, one of the leading causes of life-threatening fungal infections, opening new avenues for developing life-saving treatments.
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NewsToo much RNA can starve cells of energy
Researchers uncover a link between excess RNA and mitochondrial damage — revealing new insights into viral infections, aging and RNA-based therapeutics.
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NewsNext-gen mRNA therapeutics get a new delivery vehicle
Researchers have developed a novel way of delivering circular RNA into cells, paving way for long-lasting mRNA-based therapeutics including cancer vaccines and obesity treatments.
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NewsModeling social inequality in epidemics
New study introduces a metric into disease-transmission models which quantifies the degree to which social determinants of health — like neighborhood, access to healthcare, or economic status — cause outbreaks.
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NewsClimate change predicted to drive changes in diarrheal disease prevalence in several countries in Africa
Researchers have identified key social and environmental factors that influence how climate change affects childhood diarrheal diseases in sub-Saharan Africa.
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NewsPreventing the accumulation of mRNA-loaded lipid nanoparticles in the liver
New research has developed a novel coating agent that prevents lipid nanoparticles from accumulating in the liver—a major practical challenge when using lipid nanoparticles in vaccines and immunotherapies.
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NewsPre-existing antibodies linked to different immune responses after influenza vaccination
New study highlights how previous exposure to influenza viruses and vaccines can leave behind pre-existing antibodies, which may influence how the immune system responds to later vaccination.
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NewsDevelopment of dual-action compounds to fight cancer and infections
Researchers have developed new hybrid compounds that simultaneously reduce the viability of aggressive cancer cells and inhibit the growth of certain bacteria and fungi.
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NewsGut-pancreas immune crosstalk may offer new therapeutic strategies for pancreatic cancer
A new study reports that immune responses produced in lymph nodes shared by the liver, pancreas and intestine shape T-cell tolerance. This cross-organ immune rewiring increases T-cell infiltration into pancreatic tumors, pointing to potential new approaches for hard-to-treat pancreatic cancers.
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News‘Known’ TB gene springs to action under stress, with an unexpected biological role
New research has discovered that one of TB’s supposedly “known” genes has a completely unexpected biological role, with far-reaching implications.
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NewsPreventive TB treatment for individuals with HIV shown to be effective in real-world settings
A new study has evaluated the real-world impact of TB preventive treatment in six countries with high TB and HIV rates and highlights the importance of preventive treatment in reducing deaths caused by a curable disease.
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News35-year study reshapes our understanding of Lyme disease ecology
Researchers reveal surprising findings from one of the world’s longest-running ecological monitoring programs tracking ticks and their hosts.
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NewsEngineered macrophages gain enhanced bacteria-targeting ability
A novel membrane interface engineering strategy enables immune cells to specifically recognize, capture and eliminate pathogenic bacteria without genetic modification.
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NewsResearchers identify rapidly spreading genetic variants that make parasites resistant to malaria treatment
New genetics study helps explain declining malaria drug susceptibility and highlights the urgent need to track mutations and improve current therapies.
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NewsCells use a little-known molecule to protect themselves from iron overload
New research shows that cells rely on an unexpected protector against elevated iron levels: small molecules called polyamines. These small molecules act like storage lockers for iron, safely holding the metal in a non-reactive state until cells need it.
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NewsNovel AI model accurately detects key gene mutations and predicts biomarkers across 32 cancer types
Researchers have developed a novel AI model capable of predicting cancer subtypes, specific genetic mutations, and survival outcomes across 32 different cancers.
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NewsImmune molecules play a limited role in ALS progression
New research indicates that immune-related molecules change in motor neurons affected by amyotrophic lateral sclerosis (ALS), but they do not appear to be major drivers of disease progression.
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NewsPregnancy increases immune burden on women with arthritis and lupus
New research finds that the immune system of women with autoimmune diseases such as rheumatoid arthritis and lupus react very differently to pregnancy: rheumatoid arthritis patients often experience an improvement in symptoms, while lupus patients have an elevated risk of deterioration.
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NewsCould preventing shingles also help prevent dementia?
A new study finds that older adults who received a shingles vaccine had a 24% lower risk of developing dementia over four years. The findings add to growing evidence that preventing shingles may also protect against neurological disease.