All Editorial articles – Page 13
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Antibody-based therapy is several steps closer to treat lethal mucormycosis
A new paper discusses the use of monoclonal antibodies to target a key fungal cell surface protein, CotH, which enables the Mucorales fungus to invade human cells and cause mucormycosis, which has high mortality rates in people with weakened immune systems.
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New model predicts how bacteria navigate obstacles to spread
A scientist has developed the first analytical model for predicting how bacteria spread in environments filled with obstacles. This model will help inform strategies for curbing bacterial infections or for designing better drug delivery.
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Researchers test new, more reliable method to detect chagas disease
Researchers have successfully tested a faster, more sensitive and reliable way to diagnose Chagas disease, a debilitating parasitic illness that affects approximately 6 million people worldwide.
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Selective G6PDH inactivation for Helicobacter pylori eradication with transformed polysulfide
A new study highlights a novel mechanism of action driven by polysulfides, presenting a promising alternative strategy for combating H. pylori infections.
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Nature’s warriors: How rice plants detect and defend against viral invaders
A groundbreaking study uncovers a molecular mechanism by which rice cells perceive viral infections and initiate antiviral response, which significantly contributes to understanding of virus-host interactions for further disease resistance breeding.
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McMaster leads Canada’s first-ever guidelines for Post COVID-19 Condition
A team of experts from McMaster University has led the creation of Canada’s first-ever comprehensive guidelines for diagnosing, managing, preventing, and treating post COVID-19 condition (PCC), more commonly known as long COVID.
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Gatekeeping barriers manage communications between plants and bacteria
For over a century, the Casparian strip has been known as the root’s doorman, controlling what enters the plant. But a new study reveals it has a second job: regulating the delicate metabolic trade between plants and bacteria.
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Four advances that could change tuberculosis treatment
World Tuberculosis Day commemorates Robert Koch’s discovery of the source bacterium Mycobacterium tuberculosis. Scientists are still refining TB diagnosis methods and treatment strategies - some of the latest innovations are revealed here.
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Efficacy of topical Nigella sativa L. with vinegar in the treatment of acne vulgaris
A team of researchers in India assessed the efficacy and safety of a topical formulation combining Kalonji and Sirka for the treatment of mild to moderate acne vulgaris. The formulation was compared with a 5% benzoyl peroxide.
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Japanese plant Daphne pseudomezereum yields anti-HIV daphnane diterpenoids
Scientists have discovered for the first time that Daphne pseudomezereum (commonly known as Onishibari) contains a substance inhibiting replication of human immunodeficiency virus (HIV).
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AMI leaders join International Microbiome Meeting in San Diego
Leading scientists from around the world recently convened at the Center for Microbiome Innovation’s International Microbiome Meeting (CIMM) at the Scripps Institution of Oceanography in San Diego.
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Guardians of the vineyard: Canines and chemistry work to combat powdery mildew
Researchers are now analyzing volatile chemicals emanating from grape leaves infected by a fungus called powdery mildew with the goal of improving training for vineyard canines that use their noses to detect infected vines.
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Deadly bacteria developed the ability to produce antimicrobials and wiped-out competitors
A drug-resistant type of bacteria that has adapted to health care settings evolved in the past several years to weaponize an antimicrobial genetic tool, eliminating its cousins and replacing them as the dominant strain.
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WHO calls for urgent action to address worldwide disruptions in tuberculosis services
Since World Tuberculosis Day is only days away, World Health Organization addresses the current challenges faced by countries in TB responses. They urgently call for an united global effort to combat the deadly disease and safeguard the public health from the devastating consequences.
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H5N1 influenza viral lineages beginning to evade human immunological defenses
A new computer modelling approach predicts the protein-antibody interactions of the potentially pandemic-causing H5N1 avian influenza virus lineage. It helps to understand the viral evolution to ensure high vaccine efficacy.
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Updated guidelines for pediatric Mycoplasma pneumoniae infection
In light of the rise in antibiotic resistance, new guidelines are released with detailed recommendations of diagnosis and treatment strategies for pediatric Mycoplasma pneumoniae pneumonia (MPP), along with the means to manage severe complications.
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Hidden threat: The evolving fungus that spreads through cats and humans
Researchers have developed a better understanding about the molecular basis of the Sporothrix species in virulence and evolution, amid the largest sporotrichosis epidemic in Brazil. The identification of the genetic markers helps to enhance fungal surveillance and strengthen disease control.
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Long COVID could be causing huge economic burden annually
Behind the healthcare burden from long COVID, a study has also uncovered the economic burden of those who are more likely to suffer from long COVID through a computer simulation model of long COVID probabilities and the accompanied productivity loss.
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Researchers discover Achilles heel of Lyme disease pathogen
Researchers discovered and investigated an unique enzyme used in the pathway specific to Borrelia burgdorferi, the parasite that causes Lyme disease. The enzyme serves as the ideal genus-specific target for therapeutic intervention.
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Study identifies viruses in red tide blooms for the first time
A new study identifies viruses associated with Karenia brevis, the single-celled organism that causes red tide. By testing water samples collected from red tide blooms, the researchers found several viruses in blooms — including one new viral species.