All Editorial articles – Page 18
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siRNA plus nanovaccine yields stable functional cure for chronic hepatitis B
Researchers have developed an innovative therapy for chronic hepatitis B, synergistically combining their proprietary ferritin nanoparticle-preS1 (Ferritin-NP-preS1) therapeutic vaccine with a preclinically validated HBV-specific siRNA.
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Cutting off parasite’s energy supply could help fight malaria
Once inside the body of an infected person, the malaria parasite relies on a process called glycolysis to produce energy and stay alive. Blocking the enzymes involved in this process could cut off the parasite’s primary energy source and kill it.
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Bacteria use ancient war trick to outsmart viruses – and it could help us fight superbugs
Scientists have discovered a new type of immune defense in E. coli bacteria that turns viral infection machinery against the virus itself. They’ve named it Kongming after the Chinese military strategist who famously used enemy weapons to defeat his foes.
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Novel compound inhibits the growth of tumor-associated Fusobacteria
Researchers seeking ways to eliminate fusobacteria in carcinomas have made an unexpected discovery: their control compound, FUS79, which did not target a specific transcript, exhibited strong activity against five fusobacterial strains without affecting other tested bacterial species.
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New study reveals emerging cases of babesiosis in Mid-Atlantic region
A newly published study provides critical insights into the emergence of babesiosis in the Mid-Atlantic region, documenting human cases and the presence of Babesia microti in local tick populations.
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Pediatric investigation review discusses the challenges, innovations, and future directions in dengue vaccine development
A new review discusses the current status and implications of dengue vaccines like CYD-TDV, TAK-003, and Butantan-DV while exploring the challenges in Dengue vaccine development like ADE, and proposes future directions in this field.
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Researchers reveal core cellular network modulating immune phenotype switching in hepatitis B
A new study explores the immune dynamics across different phases of HBV infection, including acute hepatitis B, immune tolerance, immune activation, and inactive chronic infection, using single-cell RNA and TCR/BCR sequencing.
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Researchers reveal how human genetics and intratumoral microbiota affect colorectal cancer
A study shows that the single-nucleotide polymorphism (SNP) rs2355016—a tiny DNA change that some people carry—affects how intratumoral microbiota adhere to tumor cells, promoting colorectal cancer progression.
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Broader antibiotic use could change the course of cholera outbreaks, research suggests
Disease modeling research suggests that, for some cholera outbreaks, prescribing antibiotics more aggressively could slow or stop the spread of the disease and even reduce the likelihood of antibiotic resistance.
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National-level actions effective at tackling antibiotic resistance
National-level policies can reduce the impact of antibiotic resistance across diverse countries, according to a new study. The comparison of countries found that national action was consistently associated with improved indicators of antibiotic resistance.
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Fungi dwelling on human skin may provide new antibiotics
Researchers have uncovered a molecule produced by yeast living on human skin that showed potent antimicrobial properties against a pathogen responsible for a half-million hospitalizations annually in the United States.
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A hidden control center: How bacteria regulate their attack strategies
Researchers have discovered that a key bacterial protein, CsrA, gathers in a droplet-like structure inside cells to control when and how bacteria activate their disease-causing genes.
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Human protein HSF2 helps wake up sleeping cancer-linked viruses
A new study demonstrates the ability of the human protein HSF2 to remodel the viral DNA to enable the transition from dormant viral latency to active lytic reactivation.
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COVID-19 vaccinations are metabolically safe, research finds
New research confirms that multiple doses of COVID-19 vaccines do not cause significant metabolic changes, offering reassurance for those concerned about potential long-term side effects of vaccination.
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Now is the time to strengthen infection prevention and control (IPC) programs in healthcare facilities
A joint position paper urges United States healthcare facilities to elevate the standards and effectiveness of their Infection Prevention and Control (IPC) programs.
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How math helps to protect crops from invasive disease
New research demonstrates how mathematical modeling can predict outbreaks of toxic fungi in Texas corn crops—offering a potential lifeline to farmers facing billions in harvest losses.
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Measles may be making a comeback in the US, research finds
If immunization rates drop further over a prolonged period of time, measles and even other wiped-out diseases — such as rubella and polio — could one day make a comeback in the United States, according to a new study.
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Bacteria’s mysterious viruses can fan flames of antibiotic damage, according to new model
Researchers built a model that allows them to diminish phage communities from a mouse gut microbiome — and then bring them back — without affecting the bacteria. A test run found evidence that phages may increase gut bacteria’s sensitivity to antibiotics.
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Global virus network issues urgent call to action to mitigate the rising threat of H5N1 avian influenza
The Global Virus Network (GVN) has issued a call-to-action, calling on world governments to address the threat of H5N1 avian influenza by enhancing surveillance, implementing biosecurity measures, and preparing for potential human-to-human transmission.
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Every dose counts: Safeguarding the success of vaccination in Europe
Marking European Immunization Week (EIW) 2025, a new report highlights the risks of suboptimal vaccination coverage in Europe and publishes a set of operational tools that public health authorities can use to improve vaccination acceptance and uptake.