All immunocompromised articles
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NewsExpert consensus outlines 12 recommendations to prevent secondary mucormycosis after respiratory viral infections
The recommendations focus on defined high-risk patients, early viral testing and treatment, hospital infection control, and practical measures for resource-limited settings.
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NewsResearchers identify the immune cells that keep a deadly fungus in check
A new study finds that control of Cryptococcus neoformans depends not on a single immune cell type, but on several working together — a discovery that could reshape how doctors think about preventing life-threatening fungal infections.
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NewsFirst immune pathway discovered that stops a normally harmless fungus spreading through the body and causing deadly disease
An immune pathway has been discovered which prevents a normally harmless fungus developing into a fatal infection.
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NewsStudy shows breath test can confirm bacterial infection
A study shows how molecules that are only broken down by infecting bacteria, and not by gut bacteria, can be used to confirm infection. By enriching these molecules with a naturally occurring carbon isotope, the researchers found that carbon dioxide produced when they break down is easily detected in a breath test.
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NewsTarget behind cancer drug shown to help fight influenza in mice
A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza. A study found that Programmed Death-Ligand 1 (PD-L1), best known for helping tumors evade immune attack, instead helped immunocompromised mice clear flu-infected lung cells and survive infection.
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NewsLiquorice root could be effective against upper respiratory tract infections - while protecting ‘good’ microbes
Lozenges supplemented with liquorice root extract could be an effective remedy against upper respiratory tract infections while protecting microbes that are beneficial to the body, reveals a study presented at MLS Future Forum, which is supported by Applied Microbiology International.
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CareersSummer studentship: Owen investigates how fungal hyphae interact with lung cells
Owen Nicholson reports back on his AMI-sponsored summer studentship which investigated the role of Piezo1 in the immune response during fungal invasion of the human lung at the University of East Anglia.
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NewsTwo-dose recombinant shingles vaccine is effective even accounting for prior receipt of live shingles vaccine
A target trial emulation was conducted to assess the effectiveness of recombinant zoster vaccine (RZV) accounting for prior receipt of live zoster vaccine (ZVL) and immunocompetence. The results suggest individuals vaccinated with ZVL should be revaccinated with two doses of RZV.
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NewsFungal toxin offers colonization support - in small doses
The yeast fungus Candida albicans not only uses the toxin candidalysin to cause infections, but also to colonize the oral mucosa inconspicuously – but only in finely balanced amounts. Too little toxin prevents oral colonization, too much triggers the immune system.
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NewsUltra-low dose CT aids pneumonia diagnosis in immunocompromised patients
Denoised ultra-low dose CT can effectively diagnose pneumonia in immunocompromised patients using only 2% of the radiation dose of standard CT, according to a study.
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NewsVirus that causes COVID-19 can penetrate blood-retinal-barrier and could damage vision
Using a humanized mouse model, researchers have discovered the virus that causes COVID-19 can breach the protective blood-retinal barrier with potential long-term consequences in the eye.
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NewsClimate crisis could trigger outbreak of new and lethal infectious diseases
Researchers have identified Candida orthopsilosis, a hybrid microorganism that originated from two other parental fungi in a marine environment, as a potential pathogen that could pose a future threat to human health.
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NewsRare yeast pathogen causing neonatal outbreaks
Scientists studying the stubborn and dangerous rare yeast pathogen behind two outbreaks in a neonatal intensive care unit in Delhi, India, have found that while infected patients can be treated with antifungal medications, the yeast is remarkably resistant to the strong disinfectant bleach commonly used to sanitize hospital rooms.
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NewsFull ICUS and abuse of meds sparked post-pandemic outbreak of drug-resistant fungus in Brazil
Researchers in Brazil have reported the largest outbreak to date of COVID-associated candidemia caused by the same drug-resistant strain of Candida parapsilosis, a fungus that invades the bloodstream and can lead to death.