All Infection Prevention & Control articles
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CARB-X funds Peptilogics to develop a novel, broad-spectrum therapeutic to treat fracture-related infections
CARB-X will award Peptilogics US$3.3 million to develop and execute a workplan for its slow-release formulation of a novel, broad-spectrum therapeutic, zaloganan-CR, an engineered peptide intended for use in preventing infection after high-energy-traumatic bone injuries.
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Exeter launches second round of global funding to tackle antifungal drug resistance
A University of Exeter funding scheme designed to combat the global challenge of fungal antimicrobial resistance (fAMR) has announced a new call for applications.
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Tuberculosis strains resistant to new drugs are transmitted between patients
Researchers have identified 514 Mycobacterium tuberculosis strains that are resistant to TB drugs, including both old and new treatment regimens, in 27 countries across four continents. 28% of these strains were transmitted directly from one patient to another.
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As prevention strategy for sexually transmitted infections rolls out, experts highlight both promise and knowledge gaps
Real-world evidence demonstrates that the postexposure strategy of doxy PEP is reducing the rate of syphilis and chlamydia, but has had little to no effect on gonorrhea and needs close monitoring for signals of antibiotic resistance.
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New study shows plummeting STIs with doxyPEP use
A new study has found that rates of chlamydia and syphilis plummet among people prescribed doxycycline for sexually transmitted infection prevention in routine clinical care.
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Sugar solution fights infection in dairy cows just as well as antibiotics
A concentrated sugar solution could be just as effective as antibiotics at treating a common infection in dairy cows, according to a new study.
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Potentially harmful bacteria slip through antimicrobial showerheads
Researchers report that antimicrobial silver-containing showerheads are no ’silver bullet’. In real-world showering conditions, most microbes aren’t exposed to the silver long enough to be killed.
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Discovery of β‐nitrostyrene derivatives as potential quorum sensing inhibitors for biofilm inhibition in Serratia marcescens
A new study has identified β‐nitrostyrene derivatives as potential quorum sensing inhibitors for biofilm inhibition and antivirulence factor therapeutics against Serratia marcescens.
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Study assesses virulence of Cryptococcus strains, laying groundwork for improved treatment
A research group has just completed a six-year study to examine the virulence of 38 clinical isolates from various strains of Cryptococcus, taking us a step closer towards improved treatment of the fungal pathogen.
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Disney princesses face hidden health risks, including zoonotic infections, warn experts
Although Disney princesses seem to live happily ever after, they face serious real world health hazards, warn experts in the Christmas edition of the BMJ.
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Staphylococcus aureus thwarts vaccines by turning on a protein that halts immune response
Approximately 30 clinical trials to date have failed to result in an effective human vaccine for Staphylococcus aureus but researchers have now identified a key reason for these failures, indicating that it may be possible to modify the vaccines to work in humans.
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Scientists collect ‘microbial fingerprints’ found in household plumbing
Scientists sampled faucets in eight homes for seven days to see the flow and change of different bacteria populations. They found that, though houses generally shared major categories of bacteria, down to the species level, there was wide variation from house to house.
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Global research uncovers critical weakness in malaria parasite
Scientists exploring how immunity develops against Plasmodium falciparum found that broadly reactive antibodies from various individuals consistently bound to the same site on a key virulence protein of the malaria parasite.
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Federal needle exchange programs are cost-effective to reduce health care costs, blood-borne infections
Needle exchange programs are evidence-based strategies that prevent transmission of blood-borne viruses, reduce injection-related infections, improve access to medical care, and facilitate entry into substance dependence programs for people who inject drugs, says a new study.
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Breakthrough of the Year: A drug that prevents HIV infection, providing six months of protection per shot
As its 2024 Breakthrough of The Year, Science has named the development of lenacapavir – a promising new injectable drug that prevents HIV infection. The award also recognizes related work surrounding gaining a new understanding of the structure and function of HIV’s capsid protein.
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Study shows how genetic defects in Toxoplasma are rescued by co-infection
Toxoplasma gondii parasites can use secreted factors to compensate for genetic defects in neighbouring parasites, highlighting a limitation of pooled CRISPR screens.
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Research yields new model for replication of BKPyV virus, a major cause of kidney transplant failure
There are no effective antivirals against BK polyomavirus in transplanted kidneys. A better understanding of its replication will offer new ways to protect those kidneys.
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Cleaning surfaces every two hours cuts norovirus infections by 83% in airports
At airports, frequently disinfecting surfaces, mask-wearing and antimicrobial surface coatings can all help prevent the spread of norovirus, according to a new study.
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Bacterial ‘biopesticide’ against malaria mosquitoes successful in early field tests
An experimental bacteria-derived biopesticide is highly effective in killing malaria-carrying mosquitoes, including those that have developed resistance to chemical pesticides, according to initial field tests.
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Therapeutic tool inhibits the proliferation of the SARS-CoV-2 virus that causes COVID-19
A study led by the University of Barcelona and the Spanish National Research Council’s Institute for Advanced Chemistry of Catalonia (IQAC - CSIC) presents a new therapeutic tool capable of inhibiting the proliferation of the SARS-CoV-2 virus that causes COVID-19. Source: University of Barcelona The experts Verònica Noé ...