All Jiazhang Lian articles
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NewsNew evolution platform creates tougher yeast for sustainable biomanufacturing
Researchers have now developed a powerful new tool that accelerates microbial evolution. Their study introduces RAMPAGE, a programmable system that continuously generates genetic diversity across the genome of the industrial yeast P. pastoris.
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NewsBrewing a rare medicine: yeast engineered to produce a valuable astragalus isoflavonoid
By reconstructing the complete biosynthetic pathway inside Saccharomyces cerevisiae and systematically removing metabolic bottlenecks, researchers created the first yeast platform capable of producing calycosin-7-glucoside from simple carbon sources.
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NewsEngineered yeast delivers record levels of animal-free chondroitin sulfate
A new study establishes a robust yeast-based platform that overcomes the long-standing trade-off between yield and sulfation, enabling sustainable, high-level production of high-quality chondroitin sulfate without reliance on animal sources.
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NewsScientists synthesize precursors of powerful anti-cancer drug in yeast cells
Researchers have identified a novel method for the biological synthesis of catharanthine and vindoline - the two pharmacologic precursors of anti-cancer drug vinblastine - using yeast cells.