All articles by Linda Stewart – Page 38
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New guidelines unveil advanced strategies for HIV treatment and prevention
The International Antiviral (formerly AIDS) Society-USA (IAS-USA) has published new international guidelines for the treatment and prevention of HIV, based on significant advances in antiretroviral therapies and new prevention strategies such as pre-exposure prophylaxis.
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Researchers uncover role of Cul3/Diap2/Dredd axis in mediating the host antimicrobial immune defense
Researchers combined a series of genetics, immunology and molecular biology approaches to confirm that Cul3 plays an essential role in the Drosophila antimicrobial immune defense.
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β-ionone shows promise in preventing ulcerative colitis through gut barrier protection and microbiota regulation
New research demonstrates that β-ionone can alleviate ulcerative colitis symptoms in mice by protecting the gut barrier and restoring the gut microbiota, offering hope for future dietary supplements or therapeutics aimed at managing UC.
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Kim Barrett named as winner of John Snow Public Health Innovation Prize 2024
Dr Kim Barrett, vice dean for research and distinguished professor of physiology and membrane biology at the UC Davis School of Medicine, has been named as this year’s winner of the John Snow Public Health Innovation Prize 2024.
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Federal needle exchange programs are cost-effective to reduce health care costs, blood-borne infections
Needle exchange programs are evidence-based strategies that prevent transmission of blood-borne viruses, reduce injection-related infections, improve access to medical care, and facilitate entry into substance dependence programs for people who inject drugs, says a new study.
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Diverse phage populations coexist on single strains of gut bacteria
A new study shows that a single bacterial species, the host of a phage, can maintain a diverse community of competing phage species. Several phage species coexist stably on a population of a genetically uniform strain of E. coli.
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Breakthrough of the Year: A drug that prevents HIV infection, providing six months of protection per shot
As its 2024 Breakthrough of The Year, Science has named the development of lenacapavir – a promising new injectable drug that prevents HIV infection. The award also recognizes related work surrounding gaining a new understanding of the structure and function of HIV’s capsid protein.
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Researchers call for global discussion about possible risks from ‘mirror bacteria’
A group of researchers has published new findings on potential risks from the development of mirror bacteria — synthetic organisms in which all molecules have reversed chirality (i.e. are ‘mirrored’).
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Hidden threats to soil revealed in sewage sludge research
Hidden threats from the agricultural use of contaminated sewage sludge could be contributing to already diminished poor soil health, according to a new report.
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New super-enzyme could revolutionize CO₂ capture
Scientists have developed new metagenomic analysis tools to identify a super heat-resistant enzyme of biotechnological interest. The enzyme specializes in enhancing the dissolution of CO₂ in water and exhibits unprecedented stability under industrial conditions.
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Identifying amino acids that prevent sporulation in food poisoning
Scientists who examined how amino acids are involved in Clostridium perfringens spore formation have identified serine as an inhibitor. They found that serine inhibits the pathogen’s cell wall from remodeling, which is necessary in the process of becoming a spore.
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New study highlights efficiency in detecting infectious diseases
In an effort to make large-scale disease testing faster and more affordable, researchers have developed an optimized approach to pooled testing, which could transform public health screening for infectious diseases.
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Initiative to start HPV vaccination at age 9 improved completion rates
A quality improvement program designed to increase earlier uptake of the human papillomavirus (HPV) vaccine raised vaccination rates significantly, according to a study.
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A new class of antivirals could help prevent future pandemics
A new study introduces a proof-of-concept for a novel class of antivirals that would target a type of enzyme essential not just to SARS, but also many RNA viruses, including Ebola and dengue, as well as cytosolic-replicating DNA viruses, including Pox viruses.
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Study finds widening inequalities in child vaccination rates across England
Vaccine uptake was found to be consistently lower among children in areas of higher deprivation, while the number of children susceptible to measles at age 5 increased 20-fold in the most deprived areas.
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The maternal microbiome during pregnancy impacts offspring’s stem cells in mice
Gut microbiome composition during pregnancy has long-term effects on offspring stem cell growth and development, new research reveals.
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Wild bird's gut microbiome linked with its sexual ornamentation and body condition
A new study provides the first description of how a wild bird’s microbiome relates to its ornamentation and body condition. A Northern cardinal’s gut microbiome diversity can be predicted by its body condition, and the quality of its ornamentation – red plumage and beak.
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First full characterization of kidney microbiome unlocks potential to prevent kidney stones
Low levels of bacteria like E. coli and Lactobacillus in our urine come from communities in our kidneys, where they promote or prevent kidney stone formation.
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Study shows how genetic defects in Toxoplasma are rescued by co-infection
Toxoplasma gondii parasites can use secreted factors to compensate for genetic defects in neighbouring parasites, highlighting a limitation of pooled CRISPR screens.
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Updated Hep B vaccine more effective for people with HIV
A newer vaccine against hepatitis B virus was clearly superior to an older vaccine type in inducing a protective antibody response among people living with HIV who didn’t respond to prior vaccination, according to an international study.