All articles by Linda Stewart – Page 33
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NewsPhages with fully-synthetic DNA can be edited gene by gene
Scientists have developed a method to construct bacteriophages with entirely synthetic genetic material, allowing researchers to add and subtract genes at will.
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NewsNew drug target identified in fight against resistant infections
Researchers have identified new drug targets within a special repair system possessed by certain bacteria, known as Rtc, which enables them to counteract the effects of these antibiotics.
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NewsHow are metabolism and cell growth connected? — A mystery over 180 years old
A research team has identified a novel principle in biology that mathematically explains why the growth of organisms slows as nutrients become more abundant—a phenomenon known as “the law of diminishing returns.”
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NewsResearchers reveal novel mechanisms for decoding bacterial frequency modulation in signal processing
A study reveals the fundamental physical principles underlying bacterial FM signal processing, and demonstrated that FM decoding mechanisms enable bacteria to increase information entropy by approximately 2 bits compared to traditional AM in three-gene regulatory systems.
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NewsSingle-cell insights reveal how HPV status reshapes penile tumor immunity
A study found that HPV-positive tumors in penile squamous cell carcinoma cases contained fewer proliferative macrophages and less exhausted CD8+ T cells, along with stronger chemokine signaling, revealing distinct immune remodeling associated with HPV infection.
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NewsNo-needle test can tell if flu/COVID vaccines are effective
A team of researchers has developed a skin patch that can detect antibodies associated with COVID and flu infections. It’s orders of magnitude more sensitive than existing tests, uses just a half volt of electricity, and can return results in 10 minutes.
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NewsGut microbiota: implications in pathogenesis and potential therapeutic target in primary biliary cholangitis
A new review synthesizes current evidence on gut microbiota dysbiosis in PBC, elucidates its pathogenic mechanisms, and explores its potential as both a diagnostic biomarker and a novel therapeutic target.
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NewsSecrets of microbial motion: How bacteria swash, glide and shift gears to survive
Two new studies reveal surprising ways microbes move, with implications for human health and disease. The first shows that salmonella and E. coli can ’swash’ across moist surfaces even when their flagella are disabled, while the second probes the T9SS gearbox in flavobacteria.
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NewsHeatproof microbes reveal molecular secrets of nature’s hottest recycling system
This study reveals how thermophilic bacterial communities withstand temperatures of up to 87°C by remodeling their molecular machinery. Scientists uncovered a heat-defense network centered on heat shock proteins that refold damaged enzymes and preserve protein structure.
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NewsHidden HPV-linked cell type may drive early cervical cancer, scientists report
A new study identifies tumor-promoting keratinocytes linked to HPV infection and poor prognosis. Scientists employed single-cell RNA sequencing (scRNA-seq) and multiplex immunohistochemistry (mIHC) to delineate the molecular landscape of early-stage CESC.
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NewsNewly discovered host mechanism in coronaviruses
A previously unknown cellular mechanism crucial to the replication of coronaviruses has been identified: c-Jun N-terminal kinase (JNK) is activated during infection with human coronavirus HCoV-229E and mediates the phosphorylation of the viral nucleocapsid (N) protein.
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NewsFirst detection of zoonotic Rickettsia species in dog ticks from Malawi reveals potential public health risk
An international research team has reported the first molecular detection of Rickettsia bacteria in ticks collected from domestic dogs in Malawi, addressing a significant knowledge gap in understanding tick-borne disease risks in southeastern Africa.
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NewsCOVID-19 vaccination lowers long COVID risk in adolescents
Adolescents who were vaccinated against COVID-19 were less likely to develop long COVID after their first SARS-CoV-2 infection than unvaccinated peers, finds a new study.
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NewsNew study shows invasive Group A Streptococcus outcomes shaped by treatment strategies, not species lineage
Researchers highlight the role of early clindamycin prescription in improving the recovery rate of patients with invasive Group A Streptococcus infections in a study that examined the evolving epidemiology of such infections.
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NewsEvolving antibiotic resistance under pressure may lead to personalized treatment
A new study demonstrates the use of an experimental evolution approach to map genetic mutations in Acinetobacter baumannii treated with one of two uncommon antibiotics.
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NewsLow-dose cannabis compound reduces side effects of HIV treatment
Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy (ART). Benefits included increased production of serotonin, while inflammation, cholesterol and harmful secondary bile acids were all reduced.
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NewsNew nasal vaccine has potential to transform respiratory disease prevention
Researchers have demonstrated that their nasally-delivered, antibiotic-inactivated Bordetella pertussis (AIBP) vaccine not only prevents severe disease but also curbs bacterial transmission — an achievement long sought by vaccine developers worldwide.
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NewsERC Synergy Grant awarded to physicist Michael Lässig and virologist Florian Klein
Researchers have been awarded a Synergy Grant by the European Research Council (ERC) for the project CoEvolve, which investigates the co-evolution of viruses and the immune system.
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News Sea stars show surprising resilience after disease outbreak
A decade after sea star wasting disease devastated ochre sea star populations along the U.S. West Coast, new research suggests that the epidemic shifted populations from a stable, adult-dominated state to one marked by fluctuations in sea star sizes and ages.
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NewsMicroalgal-bacterial sludge offers sustainable solution for removing hormonal pollutants from wastewater
A team of researchers have revealed how microalgal-bacterial granular sludge (MBGS) can adapt and efficiently degrade estriol, a common endocrine-disrupting compound (EDC), under environmentally relevant conditions.