All articles by Linda Stewart – Page 28
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NewsA bacterial toxin can counteract colorectal cancer growth
A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. Systemic administration of the purified bacterial substance changes the immune microenvironment in tumours.
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NewsShould younger and older people receive different treatments for the same infection?
Scientists find the mechanisms young mice use to fight sepsis become disadvantageous in older age, suggesting age-specific treatments may be necessary in ongoing antibiotic resistance crisis.
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NewsGut bacteria molecule boosts lung cancer treatment response
Researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.
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NewsPlant discovery could lead to new ways of producing medicines
Scientists studying a plant called Flueggea suffruticosa, which produces a particularly powerful alkaloid known as securinine, investigated how this chemical is made - and discovered that the process is driven by a gene that looks more like it comes from bacteria than from a plant.
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NewsNew study explores therapeutic potential of CRISPRCas3 genome-editing system
Scientists working on the genetic disease transthyretin amyloidosis evaluated the efficacy of the CRISPR–Cas3 system in safely achieving a permanent reduction of transthyretin (TTR) production through genome editing of the TTR gene.
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NewsSame moves, different terrain: How bacteria navigate complex environments without changing their playbook
New research shows that a diverse group of bacteria has learned how to use the same basic movements to move through a wide range of environments no matter how complex, from unconstrained fluids to densely packed soil and tissues.
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NewsCorday Selden selected for the Oceanography Society Early Career Award
The Oceanography Society (TOS) has selected Dr. Corday Selden, an Assistant Professor at Rutgers University, as a recipient of the TOS Early Career Award, recognizing her outstanding early-career research contributions, leadership in ocean sciences, and exceptional promise for future impact in oceanography.
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NewsMaternal microbiome compound may hold key to preventing liver disease
Children born to mothers who consume a high-fat, high-sugar diet during pregnancy and breastfeeding face a higher risk of developing fatty liver disease later in life. New research suggests that risk may be reduced by supplementing with a naturally occurring compound produced by healthy gut bacteria.
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NewsA new study reveals how cholera virulence is activated
A new study provides a long-sought structural explanation of the regulatory cascade that allows Vibrio cholerae to colonize the human gut and produce the cholera toxin that causes life-threatening diarrhea.
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NewsTB and HIV treatments are not enough for a full recovery
Existing treatments control TB and HIV, but the immune system does not revert to normal, helping explain why people living with HIV remain susceptible to infections and underscoring the need for immunotherapies.
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NewsJeremy Horowitz selected for The Oceanography Society Early Career Award
The Oceanography Society (TOS) has selected Dr. Jeremy Horowitz as a recipient of the TOS Early Career Award, recognizing his outstanding early-career research contributions, impact, and promise for continued achievement in oceanography, along with his strong record of mentorship, outreach, and collaborative science.
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NewsAboard the International Space Station, viruses and bacteria show atypical interplay
In a new study, terrestrial bacteria-infecting viruses were still able to infect their E. coli hosts in near-weightless “microgravity” conditions aboard the International Space Station, but the dynamics of virus-bacteria interactions differed from those observed on Earth.
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NewsWhy don’t antibiotic-making bacteria self-destruct?
Scientists discovered a promising new antibiotic in a soil sample. The molecule, lariocidin, is produced by the microbe Paenibacillus and shows broad activity against pathogenic bacteria. Now, the researchers report how Paenibacillus avoids harm by its own antibiotic.
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NewsScientists observe infections by cancer-causing retroviruses in koalas as they occur
Scientists analysed the ongoing colonization by two retroviruses of the germline of koalas and resulting deaths from cancer in multi-generational pedigrees of over 100 koalas in US and European zoos. They calculated genetic risk scores (GRS) that can help guide koala breeding programs.
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NewsWhen a virus releases the immune brake: New evidence on the onset of multiple sclerosis
A study investigating the links between Epstein-Barr virus and multiple sclerosis shows that EBV can interfere with the control of B cells. One viral protein mimics a crucial “approval” signal that B cells usually require from other immune cells. Self-reactive B cells can then survive even when they should be shut down.
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NewsResearch reveals hidden diversity of E. coli driving diabetic foot infections
New research has shed light on the diversity and characteristics of E. coli strains that drive diabetic foot infections, providing the first comprehensive genomic characterisation of E. coli strains isolated directly from diabetic foot ulcers across multiple continents.
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NewsNew mechanism links Epstein-Barr virus to MS
Scientists investigating the links between the Epstein-Barr virus and multiple sclerosis show that when the immune system fights EBV, certain T cells – which normally attack the virus – can also react to a protein in the brain called Anoctamin-2 (ANO2), a phenomenon called molecular mimicry.
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NewsBirding enthusiasts can help songbirds avoid salmonella epidemics
Biologists are developing a tool to predict when deadly salmonella outbreaks are likely to happen in wild songbird populations so that people can protect their feathered friends by taking down bird feeders at the right time.
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NewsNot only toxic but also a nutrient: guanidine as a nitrogen source
Cyanobacteria are key ecological players of global carbon and nitrogen cycles. They are also becoming increasingly important for carbon-neutral biotechnology. They could serve as green cell factories for a light-driven and sustainable production of chemicals and fuels – a central pillar of the sustainable bioeconomy. Source: André Künzelmann/UFZ ...
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NewsGenetic risk factor and viral infection jointly contribute to MS
One of the leading triggers for multiple sclerosis (MS) is an infection with the Epstein-Barr virus. However, certain gene variants also play an important role. Researchers have shown that it is the molecular interaction between environmental and genetic risk factors that ultimately triggers the disease.