All Medical Microbiology articles
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Oral microbes linked to increased risk of pancreatic cancer
Twenty-seven species of bacteria and fungi among the hundreds that live in people’s mouths have been collectively tied to a 3.5 times greater risk of developing pancreatic cancer, a study shows.
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Gut infections often overlooked in men who have sex with men
It’s time to develop more effective ways to control and prevent sexually transmitted gut infections, urge the authors of an article that discusses discuss several sexually transmitted enteric pathogens that have become extremely multi-drug resistant.
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Blood microbial DNA distinguishes liver cancer from metastatic lesions
A simple blood test analyzing microbial DNA could help doctors tell apart primary liver cancer from colorectal cancer that has spread to the liver, according to a new study.
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Adverse event profiles following HPV vaccination in males
The safety profile among male recipients of human papillomavirus (HPV) vaccination remains a critical evidence gap. A new study presents the first systematic safety evaluation of Gardasil 9 and Gardasil in male recipients.
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New phenolic bisabolane sesquiterpenoids discovered from the marine-derived fungus Aspergillus sydowii
Three new phenolic bisabolane sesquiterpenoids (PBS) derivatives (±)-aspersydonol A (1a/1b) and aspersydonol B (2), along with 12 known analogues, have been isolated from the marine-derived fungus Aspergillus sydowii LF51.
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HPV integration: Moving from carcinogenesis mechanisms to clinical applications
The clinical significance of HPV integration into the host genome is substantial, particularly in cervical cancer screening programs. Integration testing has emerged as a valuable triage tool for detecting high-grade cervical intraepithelial neoplasia (CIN III+).
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New Center of Excellence to respond to the challenge of antibiotic-resistant bacteria
Boston Children’s Hospital and Tulane University have received $25 million in funding from NIAID/NIH to establish a Center of Excellence for Translational Research (CETR) called IMPACT (Immunization against Multidrug-resistant Pathogens: Activating T Cell Immunity).
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Type 2 diabetes may double risk of sepsis, large community-based study suggests
Living with type 2 diabetes (T2D) may double the risk of developing sepsis—with those aged younger than 60 years and men particularly susceptible, according to a long-term community-based study in Australia.
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Medications leave lasting mark on the gut microbiome, even years after use
Analysing stool samples and prescription records from over 2,500 Estonian Biobank participants, researchers found that the majority of drugs studied were linked to microbiome changes, with a substantial number of them also showing long-term effects detectable years after patients stopped taking them.
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Microbial allies: Bacteria help fight against cancer
An international team of scientists have discovered that microbes associated with tumours produce a molecule that can control cancer progression and boost the effectiveness of chemotherapy.
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Pediatric investigation study re-examines chikungunya in neglected pediatric victims
Researchers and policymakers must recalibrate their outlook on pediatric chikungunya to develop effective control measures, a new paper warns.
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Even healthy children can be severely affected by RSV
It is not only premature babies and children with underlying diseases who suffer from serious respiratory syncytial virus (RSV) infections. Even healthy, full-term babies are at significant risk of intensive care or prolonged hospitalisation – especially during the first three months of life.
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Frailty fuels gut imbalance and post-surgery gastrointestinal risks
Scientists found that residual intra-abdominal microbes, especially in frail patients, drive gastrointestinal complications after bladder cancer surgery.
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De-mystifying common misconception about the prevalence of Legionella bacteria
There is a common misconception that Legionella is only found in air conditioners and water towers - however, a new study has found people are likely exposed to the bacteria through other sources, including through soil.
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Researchers develop first-of-its-kind RNA tool to advance cancer and infectious disease research and treatment
Scientists have developed a powerful tool capable of scanning thousands of biological samples to detect transfer ribonucleic acid (tRNA) modifications — tiny chemical changes to RNA molecules that help control how cells grow, adapt to stress and respond to diseases such as cancer and antibiotic‑resistant infections.
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Are probiotics worth the cost to prevent infection after a colon removal surgery?
A study found that taking an 8-strain probiotic daily may reduce the risk of pouchitis, a common inflammatory condition that occurs after colon removal surgery for ulcerative colitis, but the treatment may not be worth the cost depending on a patient’s likelihood of flare-ups.
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One dose of antibiotic treats early syphilis as well as three doses
Researchers have found that a single injection of the antibiotic benzathine penicillin G (BPG) successfully treated early syphilis just as well as the three-injection regimen used by many clinicians. These findings from a late-stage clinical trial suggest the second and third doses of conventional BPG therapy do not provide a health benefit.
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Clinical study shows that nasal spray containing azelastine reduces risk of coronavirus infection by two-thirds
In addition to showing a marked reduction in coronavirus infections, the azelastine group also displayed fewer symptomatic SARS-CoV-2 infections, a lower overall number of confirmed respiratory infections, and, unexpectedly, a reduced incidence of rhinovirus infections, another major cause of respiratory illness.
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New pimple patches deliver a powerful remedy to unwanted zits
Researchers have designed a two-stage pimple patch set with an array of tiny spikes that grabs onto the pimple and delivers antibacterial or anti-inflammatory compounds. Human clinical trials confirmed that the pimples disappeared after seven days of treatment.
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One shot of RSV vaccine effective against hospitalization in older adults for two seasons
One shot of an RSV vaccine protects adults ages 60 or older from RSV-associated hospitalization and critical illness during two consecutive RSV seasons, according to a new study.