All Medical Microbiology articles – Page 6
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Helicobacter pylori treatment practices in the Asia-Pacific region
Researchers conducted an online survey of clinicians in the Asia-Pacific region to investigate treatment policies for H. pylori and confirmed that there is a growing consensus of the importance of primary and secondary prevention against H. pylori.
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Epstein-Barr virus worsens ulcerative colitis by triggering macrophage pyroptosis through glycolysis
The study shows that EBV infection activates pyroptosis in intestinal macrophages by upregulating glycolysis. This process leads to the release of pro-inflammatory cytokines, which further damage the intestinal barrier and worsen colitis symptoms.
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COVID-19 pandemic worsened mother and infant birth outcomes
Mothers who became pregnant after the start of the pandemic, those who experienced moderate-to-severe infections during pregnancy, and those who had infections during the third trimester were more likely to have adverse outcomes.
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Symptoms of long-COVID can last up to two years after infection with COVID-19
According to a study of the COVICAT cohort, almost one in four people infected with SARS-CoV-2 suffered from long-COVID. In more than half of them the symptoms persisted for two years.
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A*STAR spin-off NalaGenetics implements nationwide drug reaction screening for leprosy patients in Indonesia
NalaGenetics, a spin-off from A*STAR Genome Institute of Singapore (A*STAR GIS), will be transforming leprosy treatments in Indonesia with a nationwide genetic screening programme with their PGx1301 diagnostic kit.
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Lung abnormalities seen in children and teens with long COVID
An advanced type of MRI uncovers significant lung abnormalities in children and adolescents with long COVID, according to a new study. PREFUL MRI doesn’t require the use of radiation or intravenous contrast agents and can be done while the patient breathes freely.
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New paper-based device boosts HIV test accuracy from dried blood samples
Scientists have trialled a more precise medical device to measure HIV viral loads by engineering a paper device with wax-printed patterns that create precise channels and collection spots, ensuring it consistently collects the same volume of blood.
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Paxlovid’s impact on hospitalization and death in COVID-vaccinated older adults far weaker than previously thought
A new study overturns the assumption that Paxlovid’s effectiveness in reducing COVID-19 hospitalizations and deaths in unvaccinated adults also applies to vaccinated adults.
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Novel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.
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1 in 5 older adults get infections after heart surgery, and women have a 60% higher risk
One in five older adults gets an infection up to six months after heart surgery, with women far more likely to develop one, according to two studies which examined thousands of cases of coronary artery bypass grafting.
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Plague transmission may have begun a century before the Black Death, study shows
Evidence from 13th-century chroniclers and physicians indicates plague may have been involved in epidemics a century before the Black Death, a new study shows. Source: Dschingis Khan und seine Erben (exhibition catalogue), München 2005, p. 253 Conquest of Baghdad by the Mongols 1258. Right part of a double-page ...
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Researchers explore Spanish flu’s impact on Appalachia
A new book examines how the 1918 influenza pandemic disproportionately impacted Appalachian communities, exacerbating long-standing health disparities. Those included limited health care access, poor working conditions and systemic poverty.
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We know what you ate: Detailed protein maps assess intestinal health
A new method has been designed to map the near-exact molecular details of the human and bacterial protein regulations within the host-gut microbiome interactions. These proteins could be used for medical and dietary intervention to maintain intestinal health.
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CARB-X funds Peptilogics to develop a novel, broad-spectrum therapeutic to treat fracture-related infections
CARB-X will award Peptilogics US$3.3 million to develop and execute a workplan for its slow-release formulation of a novel, broad-spectrum therapeutic, zaloganan-CR, an engineered peptide intended for use in preventing infection after high-energy-traumatic bone injuries.
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Study shows drop in use of antiviral medications in young children with influenza
Despite national medical guidelines supporting the use of antiviral medications in young children diagnosed with influenza, a recent study reports an underuse of the treatment.
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New guidelines unveil advanced strategies for HIV treatment and prevention
The International Antiviral (formerly AIDS) Society-USA (IAS-USA) has published new international guidelines for the treatment and prevention of HIV, based on significant advances in antiretroviral therapies and new prevention strategies such as pre-exposure prophylaxis.
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Using antibiotics alone to treat children with appendicitis is a cost-effective and safe alternative to surgery
An analysis of data from more than 1,000 children with uncomplicated acute appendicitis found an antibiotics-only approach resulted in less pain and fewer days off from school during the first year after the initial hospital visit.
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First-of-its-kind national trial exploring potential of antibiotics for lowering c-section rates in women with obesity
A multicenter national clinical trial will study whether antibiotics given at the beginning of labor induction result in a decrease in C-sections. The trial is thought to be the first large-scale study of its kind in the United States.
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Enhanced screening methods prevent spread of drug-resistant fungal infections in hospitals
Researchers have enhanced hospital screening protocols for Candida auris, an often drug-resistant fungal pathogen. These new guidelines could promote early detection of the harmful fungus in high-risk patients and prevent hospital outbreaks.
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AI tackles huge problem of antimicrobial resistance in intensive care
Artificial intelligence (AI) can provide same-day assessments of antimicrobial resistance for patients in intensive care – critical to preventing life-threatening sepsis.