All Medical Microbiology articles
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Common painkillers linked to antibiotic resistance
Ibuprofen and paracetamol are common over-the-counter medications that many of us reach for when we’re sick. But new research shows that these trusted staples are quietly fuelling one of the world’s biggest health threats: antibiotic resistance.
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Gut bacteria can reveal colorectal cancer
Researchers identified all human gut bacteria to a level of detail that uncovers the physiological importance of the different microbial subgroups. This inventory was then used to detect the presence of colorectal cancer according to the bacteria present in simple stool samples.
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A microbial DNA signature differentiates two types of cancer in the liver
Researchers have identified a microbial DNA signature in blood plasma that reliably differentiates primary liver cancer from colorectal cancer that has spread to the liver (metastatic colorectal cancer).
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One universal antiviral to rule them all?
Taking inspiration from a rare mutation that makes people impervious to viral diseases, a researcher is developing a therapy that could bestow this superpower on the rest of us. The mutation causes a deficiency in an immune regulator called ISG15.
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CRISPR-based therapeutics hold potential to combat AMR and cure chronic viral infections, says GlobalData
CRISPR-based therapeutics show potential to combat antimicrobial resistance (AMR) and deliver functional cures for chronic viral infections, says GlobalData, a leading data and analytics company.
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Mount Sinai creates first manual for treating infection-associated chronic illness for clinicians
Mount Sinai has launched the country’s first clinical manual for treating infection-associated chronic illnesses (IACIs). This comprehensive guide, prepared by the Cohen Center for Recovery From Complex Chronic Illnesses, part of the Department of Rehabilitation and Human Performance, will help clinicians better diagnose and care for patients with conditions such ...
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‘Controlled evolution’ dramatically boosts pDNA production for biomedical manufacturing
Researchers have controlled the evolution of E. coli bacteria in the lab in order to dramatically increase the amount of plasmid DNA (pDNA) these modified bacteria produce. pDNA is an essential – and expensive – ingredient in many gene therapies.
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Bacterial protein therapy shows promise as first-ever antidote for carbon monoxide poisoning
Researchers have engineered a new molecule that appears promising as an effective antidote for carbon monoxide poisoning with fewer side effects than other molecules currently being tested.
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Scientists find a microbial molecule that restores liver and gut health
Researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure. The treatment may offer a new, non-toxic way to prevent and treat non-alcoholic fatty liver disease (NAFLD).
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As school returns, so do infections & asthma emergencies. Where kids live can make it worse
A new study highlights how neighborhood conditions shape the seasonal surge of virus-triggered asthma emergencies. It found that children in under-resourced communities face sharply higher rates of asthma flare-ups tied to viral infections during the first weeks of school.
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Multidrug-resistant bacteria spread from war-zone hospitals to other countries
After Russia’s full-scale invasion, thousands of patients were transferred from Ukraine to other European countries. Researchers in Helsinki found that 8% of Ukrainian refugees had been hospitalised due to war injuries. Almost 80% of them carried multidrug resistant bacteria.
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Researchers identify a potential biomarker for long COVID
Researchers have identified a potential biomarker for long COVID. The study results detail the detection of SARS-CoV-2 protein fragments within extracellular vesicles (EVs) — tiny, naturally occurring packages that help cells share proteins, metabolites, and other materials.
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New hydrogel-based treatment accelerates infected wound healing and balances skin microbiota
A novel ε-poly-L-lysine-loaded sodium-alginate/gelatin hydrogel (PSG15) has shown exceptional promise in accelerating the healing of infected wounds. The injectable hydrogel delivers antibacterial properties while regulating macrophage polarization and stabilizing the skin microbiota.
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Disarming a hidden killer: Predicting – and preventing – C. diff before it strikes
Researchers have developed a powerful, personalized modeling framework to predict whether Clostridioides difficile is likely to colonize an individual’s gut, and to test whether specific probiotic therapies might prevent and/or reverse that colonization.
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Anti-neuroinflammatory natural products from isopod-related fungus now accessible via chemical synthesis
Herpotrichone is valued for its ability to suppress inflammation in the brain and protect nerve cells, but could only be obtained in minute quantities from fungi that are symbiotic with isopods. Researchers have succeeded in chemically synthesizing this rare natural product.
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Regional differences in antibiotic use in newborns
There are relatively large regional differences in Sweden in the proportion of newborns receiving antibiotics for suspected sepsis, according to a study. The researchers want to call attention to overuse as well as highlight good examples.
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Researchers debunk long-standing concern about flu treatment in children
Researchers have debunked a long-standing theory about oseltamivir, known as Tamiflu. Oseltamivir treatment during flu episodes was associated with a reduced risk of serious neuropsychiatric events, such as seizures, altered mental status and hallucination.
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Skin test reagent proves effective and safe for TB diagnosis in children
A new class of skin test reagents based on Mycobacterium tuberculosis (MTB)-specific antigens has been developed. A phase III clinical trial suggests that C-TST is an effective and safe option for diagnosing pediatric TBI.
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Scientists pinpoint optimal dose of methylprednisolone for treating severe Mycoplasma pneumoniae pneumonia
Investigators have compared the efficacy of low- versus high-dose of methylprednisolone in preventing pulmonary lesions in children with severe Mycoplasma pneumoniae pneumonia.
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Immunoglobulin replacement therapy shows no reduction in serious infections for patients with CLL
In patients with chronic lymphocytic leukemia (CLL), regular treatment with immunoglobulin replacement therapy was not associated with a reduced risk of serious infections requiring hospitalization, according to a study published in Blood Advances.