All Medical Microbiology articles – Page 18
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NewsAstragalus polysaccharide enhances voriconazole metabolism under inflammatory conditions through the gut microbiota
Astragalus polysaccharide alleviates the reduction of VRC metabolism induced by LPS by inhibiting lipid accumulation and inflammatory cytokine levels in the serum and liver and improving the metabolic function of the liver, a new study shows.
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NewsStudy identifies immunity threshold for protection against COVID-19 in children
Researchers have found rather than antibodies, other arms of the immune system – T cells and memory B cells – provide durable protection against symptomatic SARS-CoV-2 infection in children.
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NewsNano-drugs hitching a ride on bacteria could help target hard-to-reach pancreatic cancer
Employing bacteria to infiltrate the dense matrix of collagen and other tissues surrounding pancreatic tumors and deliver drugs could aid treatment for pancreatic cancer.
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NewsNew strategy could lead to universal, long-lasting flu shot
Researchers have opened a new avenue in the attack against influenza viruses by creating a vaccine that encourages the immune system to target a portion of the virus surface that is less variable.
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NewsPioneering oral fungal infection treatment shows promise in preclinical trials
A novel oral amphotericin B (MAT2203) developed for treatment of invasive mucormycosis (IM) and other deadly invasive fungal infections, has demonstrated encouraging results in a series of preclinical studies.
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NewsStudy highlights importance of early interventions to combat HIV
Researchers have investigated the impact of treatment initiation timing on the characteristics of HIV reservoirs, a major obstacle to eradicating the virus.
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NewsChatGPT failed when challenging ESCMID guideline for treating brain abscesses
A new study has found that while ChatGPT seems able to give recommendations on key questions about diagnosis and treatment of brain abscesses in most cases, some of the AI model’s responses could put patients at risk.
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NewsNonalcoholic fatty liver disease: changes in gut microbiota and blood lipids
This study aimed to explore differences in the gut microbial community and blood lipids between normal livers and those affected by NAFLD using 16S ribosomal deoxyribonucleic acid sequencing.
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NewsTreatment for deadly superbug C. diff may be weakening
The antibiotic vancomycin, recommended as first-line treatment for infection caused by the deadly superbug C. difficile (C. diff), may not be living up to its promise, according to new research.
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NewsCocktails of antibiotics, probiotics and prebiotics hold promise in treating a common form of irritable bowel syndrome
Personalised “cocktails” of antibiotics, probiotics and prebiotics hold great promise in the treatment of a common form of irritable bowel syndrome (IBS), a new study suggests.
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NewsMaking transfusion-transmitted malaria in Europe a thing of the past
The current strategy used in Europe to mitigate malaria transfusion risk is efficient with just 10 reported cases over the past 20 years, but current serological tests used to identify “at risk” donors are not sensitive enough to completely eliminate the risk.
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NewsExperimental NIH malaria monoclonal antibody protective in Malian children
One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country’s six-month malaria season, according to the results of a mid-stage clinical trial.
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NewsAntibiotic use in patients hospitalised with COVID-19 appears to have no beneficial effect on clinical outcomes
An analysis of more than 1,300 German adults hospitalised with moderate COVID-19 finds treatment with antibiotics was associated with five times greater likelihood of COVID-19 deterioration compared to patients not given antibiotics.
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NewsPaclitaxel-induced immune dysfunction and activation of transcription factor AP-1 facilitate Hepatitis B virus replication
A study finds that Paclitaxel treatment directly promotes HBV replication and transcription, leading to HBV reactivation in HBV stable expression cell models, HBV natural infection cell models, and HBV transgenic mouse models.
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NewsNanoparticle enhances antibacterial sonodynamic therapy for eradication of Pseudomonas aeruginosa biofilm
A novel ultrasound-launched targeted nanoparticle was developed to universally destroy biofilm, target bacteria, deliver antibiotics, and efficiently kill bacteria via ultrasonic cavitation and antibacterial sonodynamic therapy.
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NewsScientists develop innovative maleic acid-treated bacterial cellulose gel enhancing bone repair
Due to its unique 3D network structure, impressive mechanical properties, and excellent biocompatibility, bacterial cellulose has emerged as a captivating area of research in the realm of scaffold fabrication.
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NewsResearchers find no link between COVID-19 virus and development of asthma in children
Researchers have found that a SARS-COV-2 infection likely does not increase the risk of asthma development in pediatric patients.
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NewsMechanism of action of the hepatitis B and D virus cell entry inhibitor bulevirtide deciphered
An international research team has succeeded in deciphering the molecular structure of bulevirtide in complex with the HBV/HDV receptor NTCP at the molecular level.
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NewsTransmission risk of multidrug-resistant bacteria appears highest in hospital sinks
An outbreak in a pediatric hospital ward in Tokyo underscores the challenge of eliminating these bacteria from a healthcare facility.
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NewsChatGPT could help reduce vaccine hesitancy and provide helpful advice on STIs
A pilot study shows the potential for using AI chatbots to assist public health campaigns in reducing vaccine hesitancy as well as providing helpful advice on STIs and access to care.