More USA & Canada News – Page 120
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NewsEngineered bacteria paint targets on tumors for cancer-killing T cells to see
Columbia engineers are the first to program bacteria to act as beacons that guide the activity of engineered T cells. This work is also the first to design interactions between these two “living” medicines to enable targeting of a range of solid tumor.
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NewsStudy reveals how young children’s immune systems tame SARS-CoV-2
A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood.
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NewsResearchers ID genes that correlate with early colonization in fecal microbe transplants
Researchers found 19 Bacteroides vulgatus genes that were unique to three strains that show early engraftment in patients after a fecal transplant, as opposed to seven strains that did not show early engraftment.
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NewsOld Faithful Geyser environment promotes genomic diversity
More strains of extremophile Thermocrinis are found in Old Faithful than in any other non-geysing hot spring in Yellowstone, suggesting that the dynamic environment promotes genomic diversity.
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NewsEngineered bacteria guide CAR-T cells to poorly infiltrated solid tumors
A new probiotic-guided chimeric antigen receptor (CAR)-T platform uses engineered bacteria to infiltrate and produce synthetic antigen targets, enabling CAR-T cells to find, identify, and destroy tumor cells in situ, according to a new study.
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NewsUsing different flours for sourdough fosters different bacteria – and flavours
A new study of the microbial ecosystem in sourdough finds that using different types of flour fosters distinct bacterial communities, and that these differences contribute to the variation of sourdough aromas and flavours.
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NewsAI tool can help forecast viral outbreaks
A new AI tool called EVEscape uses evolutionary and biological information to predict how a virus could change to escape the immune syste, and successfully predicted the most concerning new variants that occurred during the COVID-19 pandemic.
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NewsA mother mouse needs a diverse gut microbiome to form a healthy placenta
Pregnant mice with no gut microbiome or diminished microbiomes aren’t able to form the healthy placentas necessary for proper fetal development, but supplementing these mice with short-chain fatty acids promotes healthy placental development.
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NewsWorld-first comprehensive pan-genome analysis of lactic acid bacteria
A team of international researchers has published the first comprehensive comparative pan-genome analysis of lactic acid bacteria (LAB), a family of microorganisms essential to natural ecosystems and the food industry.
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NewsTB vaccine discovery paves path to end no. 1 killer of people living with HIV
Scientists have discovered a tuberculosis (TB) vaccination strategy that could prevent the leading cause of death among people worldwide living with HIV.
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NewsRemains of 1918 flu pandemic victims contradict belief that healthy young adults were particularly vulnerable
New analysis of the remains of victims of the 1918 influenza pandemic, which killed an estimated 50 million people worldwide, contradicts the widespread belief the flu disproportionately impacted healthy young adults.
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NewsPrior exposure to common virus shields against birth defects and miscarriage
A new study uncovers how pre-existing immunity to Cytomegalovirus (CMV) may significantly reduce the risk of birth defects and miscarriage during pregnancy, offering hope for a future vaccine.
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NewsWastewater surveillance research provides 12-day lead time for RSV season
Researchers using wastewater surveillance over conventional indicators have predicted the start of the annual respiratory syncytial virus (RSV) season 12 days early, providing more lead time for hospital preparedness.
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NewsSingle vaccine shot could thwart eight hospital superbugs
A single dose of an experimental vaccine, administered in mouse models, can provide rapid protection against eight different bacteria and fungi species.
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NewsResearchers receive international funding to study spiderwebs as biosensors
The dew-covered spiderweb you see in your yard might soon become a platform to detect airborne viruses, according to Jiangtao Cheng, who hopes to build bio-inspired technology that could serve as an early warning system for pathogens.
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NewsScientists discover alternative base modification for mRNA therapeutics
Researchers have incorporated a newly discovered base, called base Z, into mRNA to create Z-mRNA that has improved translational capacity, decreased cytotoxicity and drastically reduced immunogenicity compared to unmodified mRNA.
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NewsEmerging diseases threatening trees around the world are accelerating
A study analyzing more than 900 new disease reports on 284 tree species in 88 countries found that the number of new disease emergences globally is doubling every ~11 years, with pines accumulating the most new diseases.
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NewsNew recommendation on meningitis vaccines for infants in sub-Saharan Africa
An IDCRC study assessing the meningococcal pentavalent (five in one) vaccine for infants in Africa shows vaccine provides protection against meningococcal meningitis.
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NewsAcid-tolerant yeast engineered to produce valuable organic acid from plants
Researchers have engineered an acid-tolerant yeast to economically produce succinic acid, a key chemical in food, agricultural and pharmaceutical products, savings on money and emissions.
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NewsResearcher awarded $1.9m to develop model to test phages in the gut
Bryan Hsu, an assistant professor of biological sciences at Virginia Tech, has received a five-year $1.9 million award to develop a model to test the role of lytic bacteriophages, or phages as they are commonly called, in the mammalian gut.