All Probiotics, Prebiotics & Synbiotics articles
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NewsResearchers make probiotic safer for immunocompromised patients
Researchers have modified a probiotic yeast to make it safer for use by immunocompromised people, older adults and infants. Testing in an animal model found the modified yeast is less likely to cause infection than unmodified strains of the same organism.
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NewsTargeting the gut–lung microbiome to reduce infections in severe pancreatitis
Researchers report new clinical evidence that a fungal probiotic may reduce hospital-acquired infections in patients with severe acute pancreatitis. Patients receiving Saccharomyces boulardii alongside standard enteral nutrition experienced significantly fewer infections than those receiving nutrition alone.
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NewsAkkermansia muciniphila PROBIO therapy promotes arginine biosynthesis and reverses reproductive impairments in polycystic ovary syndrome rats
A research study investigated the therapeutic potential of Akkermansia muciniphila PROBIO (AP) in a dehydroepiandrosterone-induced PCOS rat model, revealing significant improvements in reproductive and metabolic parameters through modulation of gut microbiota and enhancement of arginine biosynthesis.
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NewsTrust your gut to heal your brain
Researchers have found that short-term antibiotic treatment significantly reduced neuroinflammation and neurodegeneration following traumatic brain injury (TBI) by altering the gut microbiome in animal models.
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NewsStudying yeast in the gut could lead to new, better drugs
A new study sheds light on the behavior of yeast cells in the gut, paving the way for new lines of yeast that more efficiently produce therapeutic drugs tailored to address specific diseases.
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NewsPersonalized predictions of probiotic and prebiotic therapy success by computer models
A new study demonstrated that computer models of gut metabolism can predict which probiotics will successfully establish themselves in a person’s gut and how different prebiotics affect production of health-promoting short-chain fatty acids.
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FeaturesThe world’s fermented foods in health and history
The use of microbes in food fermentation dates back thousands of years; archaeological evidence suggests that fermented beverages such as rice wine were produced in China as early as 7000 BC, while bread and beer were staples in ancient Egypt.
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NewsMissing microbes in UK infant gut and probiotics highlighted by global microbiome atlas
A global atlas mapping two key gut bacteria in infants around the world has uncovered a treasure trove of bacterial strains adapted to the infant gut and not found in commercial probiotic products. It lays the foundation for more effective, tailored infant probiotics.
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NewsGlobal scientific paper establishes first consensus definition of gut health
A global group of 13 scientists and clinicians is helping establish clarity by publishing a consensus definition of gut health. They define gut health as “a state of normal gastrointestinal function without active gastrointestinal disease and gut-related symptoms that affect quality of life.”
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NewsLactobacillus rhamnosus L34: Native probiotic that reduces inflammation in patients with chronic kidney disease
Researchers in Thailand have discovered a native probiotic strain, Lactobacillus rhamnosus L34, that helps reduce uremic toxins and inflammation-related cytokines in patients with chronic kidney disease (CKD) before dialysis.
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NewsScientists create ‘smart underwear’ to measure human flatulence
Scientists have created Smart Underwear, the first wearable device designed to measure human flatulence. The device helps scientists revisit long-standing assumptions about how often people actually fart. It also opens a new window into measuring gut microbial metabolism in everyday life.
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News‘Hidden’ bugs in our gut appear key to good health, finds global study
A single group of bacteria has repeatedly shown up in high numbers in the gut microbiomes of healthy people. Scientists found the level of CAG-170 bacteria present was consistently higher in healthy people than those with diseases including inflammatory bowel disease, obesity and chronic fatigue syndrome.
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NewsPlants influence the composition and function of their surrounding microbiome to suit their needs
An investigation into plant–microbe interactions at the genetic, metabolic and physiological levels revealed that 203 bacterial gene sequences were strongly shaped by the host plant, for example through their metabolic products. One bacterial genus was found to enhance root development even in nitrogen-limited soils.
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FeaturesGut microbiome and obesity: what we know - and what we don’t
Dysbiosis is defined as an imbalance in the composition and function of the gut microbiota. This imbalance can lead to dysregulated interactions within the bacterial community and between microbes and the host, and it can be associated with disease states. However, discussions of dysbiosis often rely on simplified dichotomies, such ...
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NewsProbiotics combined with antidiabetic drugs overcome the ‘drug black hole’
A new study addressing the ’microbial drug black hole’ proposes a new microbe–drug synergistic therapeutic strategy and advances the development of precision nutrition-based interventions for type 2 diabetes mellitus.
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NewsProject to combat childhood diarrhea receives over 5 million euros
A new project will use probiotics, improved education in hygiene and advanced mathematical models to prevent children from dying of diarrhea in low and middle-income countries.
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NewsProbiotic living microneedles designed by interbacterial competition for accelerated infected wound healing
Probiotic therapy offers a promising strategy for chronic infected wound management. Inspired by bacterial competitive interactions, researchers developed a multifunctional microneedle (MN) platform to overcome the limitations of weak competitiveness and poor penetration across biofilm barriers.
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NewsRibosomal engineering creates ‘super-probiotic’ bacteria
Using ribosome engineering (RE), researchers introduced mutations affecting the protein synthesis mechanism of probiotic Lacticaseibacillus rhamnosus GG (LGG). These mutant LGGs exhibit altered surface protein expression, including increased presentation of so-called “moonlighting proteins.”
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NewsProbiotics can restore gut microbiome in breastfed infants
A new study has found that supplementing exclusively breastfed infants with a probiotic, Bifidobacterium infantis EVC001, between 2 and 4 months of age can successfully restore beneficial bacteria in their gut.
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NewsStudy reveals high stakes of early immune development—and a potential probiotic fix
Scientists find that certain gut bacteria are essential for building immune defenses during infancy, pointing to new strategies for protecting children’s health. They have identified a way to preserve healthy immune development even when infants need antibiotic treatment.