All Proteomics & Enzymology articles
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News Ribosome profiling identifies thousands of new viral protein-coding sequences
With the help of a technique called Massively Parallel Ribosome Profiling (MPRP), scientists have identified more than 4000 open reading frames (ORFs) across 679 human-associated viral genomes.
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NewsScientists target viral enzymes to strengthen brain immunity against HSV-1
A new study uncovers how HSV-1 disables the brain’s antiviral defense—and how this defense can be restored. The study offers a promising new therapeutic strategy for treating HSV-1 encephalitis by reactivating the host’s intrinsic immune system.
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NewsResearchers reveal lipid-based communication between body and gut microbes
A new study shows how a host protein can specifically recognize bacterial lipids, thus triggering beneficial immune responses. It also highlights a new way the body actively shapes the gut microbiome by communicating with microbes to maintain balance.
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NewsScientists ID previously unknown enzymes that can produce potentially antimicrobial agents
Micro-organisms generate potential agents for combating bacteria and fungi. Researchers have identified and optimized enzymes that can specifically generate a certain functional group of these natural substances, expanding the toolkit of potential agents.
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NewsPredictive AI model can help build vaccines for future versions of a virus
Researchers have created an AI tool called EVE-Vax that can predict and design viral proteins likely to emerge in the future. For SARS-CoV-2, panels of these “designer” proteins triggered similar immune responses as real-life viral proteins that emerged during the pandemic.
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NewsStudy identifies how malaria can lead to childhood cancer
New data has uncovered the role of Plasmodium falciparum infection (malaria) in the development of Burkitt lymphoma (BL), the most common childhood cancer in equatorial Africa and New Guinea.
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NewsNew tool for cutting DNA offers promising prospects for biotechnology
Researchers have developed a new genetic tool based on a family of specific enzymes called Ssn that allows targeted cuts to be induced exclusively in single-stranded DNA. They focused on one of these enzymes in the bacterium Neisseria meningitidis.
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NewsPlastic-degrading enzymes from landfills
Researchers identified and analysed the structure and predicted functions of potential plastic-degrading enzymes in collected landfills sample from around the world, in an effort to reduce plastic pollution.
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NewsWithout oxygen: How primordial microbes breathed
Scientists decode the fundamental mechanisms of a cell respiratory enzyme in ancient bacterial cells, with potential applications in removing greenhouse gases and drug development against pathogens.
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NewsIntranasal herpes infection may produce neurobehavioral symptoms, study finds
A new study finds that herpes infection through the nose can lead to anxiety, motor impairment and cognitive issues. The research is the first to show that, by exploiting a cellular enzyme, the virus can produce behavioral symptoms.
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NewsDiscovery of a common ‘weapon’ used by disease-causing fungi could help engineer more resilient food crops
The discovery of a powerful “weapon” used by many disease-causing fungi to infect and destroy major food crop staples, such as rice and corn, could offer new strategies to bolster global food security
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NewsResearchers uncover how Staphylococcus aureus ‘steals’ iron from our blood during infections
Researchers have revealed how Staphylococcus aureus bacteria extract iron from hemoglobin – a process crucial to their survival during infections. The study has identified the full sequence of protein–protein interactions during this iron ‘theft’.
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NewsScientists recode the genome for programmable synthetic proteins
Synthetic biologists were able to re-write the genetic code of an organism — a novel genomically recoded organism (GRO) with one stop codon — using a cellular platform that they developed enabling the production of new classes of synthetic proteins.
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NewsNew study uncovers key differences in allosteric regulation of cAMP receptor proteins in bacteria
A new study provides key insights into how bacterial cAMP receptor proteins (CRPs) respond differently to the ubiquitous signaling molecule, cyclic AMP (cAMP), challenging the assumption that structural similarity predicts functional behavior in allosteric proteins.
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FeaturesArchaea: taking biocatalysis to the extreme
Despite increasing interest, archaea remain hugely understudied in comparison to their bacterial counterparts.
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NewsHealthy gut bacteria that feed on sugar analyzed for the first time
A microbe found in the lower part of the gut that is associated with good health has been comprehensively analysed and found to have a focused diet breaking down sugars locked away in mucus.
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NewsStudy reveals how microbes help detoxify our atmosphere
A new study from the Greening Lab reveals at an atomic level how microbes consume carbon monoxide present in the atmosphere. They use a special enzyme, called the CO dehydrogenase, to extract energy from this universally present but highly toxic gas.
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NewsOcean microbe’s unusual pair of enzymes may boost carbon storage, study suggests
Scientists have discovered multiple forms of a ubiquitous enzyme in microbes that thrive in low-oxygen zones off the coasts of Central and South America.
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NewsResearchers uncover role of Cul3/Diap2/Dredd axis in mediating the host antimicrobial immune defense
Researchers combined a series of genetics, immunology and molecular biology approaches to confirm that Cul3 plays an essential role in the Drosophila antimicrobial immune defense.
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NewsNew super-enzyme could revolutionize CO₂ capture
Scientists have developed new metagenomic analysis tools to identify a super heat-resistant enzyme of biotechnological interest. The enzyme specializes in enhancing the dissolution of CO₂ in water and exhibits unprecedented stability under industrial conditions.