All Proteomics & Enzymology articles
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NewsDiscovery of bacterial proteins that induce asexual reproduction in insects
From microbes in the human gut to symbiotic algae in coral reefs, research in recent decades has increasingly revealed the pivotal roles that microorganisms (or microbial species) play in shaping the biology of host organisms and of broader ecosystems. For example, some endosymbionts—microbes that live within the cells of a ...
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NewsResearchers uncover key biomolecule involved in whooping cough infection
Researchers have identified a new complex-carbohydrate biomolecule, or glycan, that plays a key role in the nasal colonization of the Bordetella bacteria responsible for whooping cough.
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NewsResearch uncovers a new path to drug diversity
By exploring protein evolution, scientists have found new “fusion sites” that enable faster and more targeted drug development.
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NewsMembrane-producing enzyme offers promising target
The enzyme LpxC, which catalyzes the first irreversible step in the biosynthesis of the outer membrane of Gram-negative bacteria, is a highly promising target for the development of antibiotics.
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NewsMutation linked to neurological disorders delivers double-pronged attack at cellular level
A mutation linked to neurological disorders knocks out not just one protein involved in translating the genetic code, but the entire cellular translation machinery. That’s the discovery of a team from the University of Maryland who were investigating how editing defects in threonyl-tRNA synthetase (ThrRS) work at ...
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NewsDiscovery opens new possibilities for maximizing nitrogenase’s potential
Researchers have discovered two essential electron carriers which play a key role in determining the performance of iron (Fe) nitrogenase, thus opening up new possibilities for elucidating and maximizing nitrogenase’s potential.
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NewsAI provides the most complete map of interactions key to bacterial survival
Researchers have produced the most complete map of the bacterial essential interactome, i.e. how proteins combine and interact to perform functions essential for their survival.
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NewsDNA particles that mimic viruses hold promise as vaccines
Using a DNA-based scaffold carrying viral proteins, researchers created a vaccine that provokes a strong antibody response against SARS-CoV-2.
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NewsViral protein fragments may unlock mystery behind serious COVID-19 outcomes
‘Zombie’ virus fragments continue to cause inflammation after the virus is destroyed, a new study finds.
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NewsScientists uncover how coronavirus defends itself against our immune system
A research team identifies “protective switches” in the protein of the SARS-CoV-2 virus.
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NewsProtein may be the ‘glue’ that helps COVID virus stick
A study found that perlecan LG3 – a protein most commonly found in blood vessels and the brain – readily formed a stable bond with the COVID spike protein and perhaps enhanced the virus’ ability to bind with cells.
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NewsScientists make COVID receptor protein in mouse cells
Initially motivated to make receptor-based sensors and therapies for COVID-19, scientists develop general strategy for producing other complex proteins.
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NewsBioExcel-CV19 offers breakthrough in understanding COVID-19 proteins
Designed to meet the urgent need for insights into the molecular intricacies of SARS-CoV-2 infection, BioExcel-CV19 is a repository for Molecular Dynamics (MD) simulations.
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NewsResearchers uncover how molecular freight elevators work in pathogenic bacteria
Researchers studying bacterial membrane transporters have studied the interaction between the transporter and its soluble substrate binding protein, showing that they adapt precisely to each other during the transportation process.
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NewsResearchers discover molecular ‘barcode’ used by bacteria to secrete toxins
Researchers have discovered a molecular “barcode” system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.
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NewsResearchers develop novel solution for Pichia pastoris enzyme production platform
A new study outlines a novel approach in enzyme production, harnessing the untapped potential of cyanobacterial biomass within the P. pastoris platform.
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NewsScientists reveal rare enzyme role change with bacterial defense system assembly
A never-before-seen phenomenon in a protein: alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.
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News Study reveals Zika’s shape-shifting machinery—and a possible vulnerability
Zika’s crucial enzyme performs multiple tasks, but a wrench in the system could bring it to a screeching halt.
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NewsBacteria engineered to biosynthesize intricate protein complexes
Researchers have developed an innovative bioengineering approach using genetically modified bacteria that can incorporate protein cages around protein crystals, producing highly customized protein complexes.
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NewsReduced activity of key enzyme linked to microcephaly in Zika-infected offspring
Researchers have shown that brain activity of Ndel1, an enzyme that plays an important role in neuron differentiation and migration, decreased in mice infected by Zika during pregnancy.
