All Proteomics & Enzymology articles – Page 5
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NewsPeptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells
The synthetic peptide was inspired by ACE2, the protein to which the virus that causes COVID-19 binds to invade human cells. The results point to a route for the development of novel antivirals.
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NewsStudy unveals a novel protective mechanism in bacterial cell wall
Researchers from Umeå University, Sweden, and Cornell University, USA, have discovered a widespread mechanism in bacteria that enhances the bacteria’s defense against environmental threats. Source: Umeå University Sara Hernandez and Laura Alvarez, two of the researchers behind the study in the lab. The discovery, which may be ...
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NewsBacterial ‘flipping’ allows genes to assume different forms
A new study has shown that inversions, which cause a physical flip of a segment of DNA and change an organism’s genetic identity, can occur within a single gene, challenging a central dogma of biology — that one gene can code for only one protein.
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NewsScientist devises test feed for fungal ‘micro-machine’ that breaks down wood
Researchers investigating a molecular machine found in fungi that decomposes wood into its basic components have come up with a test feed that allows them to observe its close-to-natural action, opening the door to putting it to industrial application.
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NewsScientists unveil how the oceans’ most abundant bacteria impact global nutrient flows
A new paper has revealed how key bacterial proteins contribute to global carbon, sulfur and other nutrient cycles.
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NewsExtreme microbe reveals how life’s building blocks adapt to high pressure
An AI tool has helped scientists discover how the proteins of a heat-loving microbe respond to the crushing conditions of the planet’s deepest ocean trenches, offering new insights into how building blocks of life might have evolved under early Earth conditions.
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NewsScientists close in on mystery of deadly Hep C virus
A new study by a cross-disciplinary research team has identified the protein complex at the surface of the hepatitis C virus that enables it to bind to human cells, opening a pathway to vaccine candidates that can prevent the virus from infecting the cells.
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NewsStudy of mosquito spit could lead to therapies for viruses like West Nile and yellow fever
Researchers are analyzing samples of noninfectious mosquito saliva in the fight against arboviruses — viruses spread by arthropods like mosquitoes.
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NewsSurprise find in study of environmental bacteria could advance search for better antibiotics
In what they labeled a “surprising” finding, researchers studying bacteria from freshwater lakes and soil say they have determined a protein’s essential role in maintaining the germ’s shape.
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NewsResearchers find promising new weapon against certain types of antibiotic-resistant bacteria
Researchers have discovered a new combination of substances that appears to combat a range of bacteria that causes conditions such as stomach ulcers and urinary tract infections, and that are increasingly developing antibiotic resistance.
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NewsStudy reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease
Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease.
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NewsMarine algae use massive enzymes of unprecedented size to biosynthesize fish-killing toxins
Marine algae Prymnesium parvum use massive enzymes dubbed PKZILLAs – some of the largest proteins ever to be identified in nature – to make large and complex prymnesin neurotoxins responsible for mass fish kills during harmful algal blooms worldwide.
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NewsScientists get to the bottom of COVID’s worst pediatric complication
Scientists investigating multisystem inflammatory syndrome in children (MIS-C) found their immune systems had latched onto a part of the coronavirus that closely resembles a protein found in their bodies, launching an attack on their own tissues.
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NewsEnzyme discovery could lead to anti-bacterial pesticides targeting plant disease
Researchers investigating Xanthomonas plant pathogens have identified XccOpgD, a glycoside hydrolase (GH186) that plays a pivotal role in the biosynthesis of CβG16α, which suppresses essential plant defense mechanisms.
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NewsStudy identifies protein that affects health of gut microbiota and response to bacterial infection
A new study shows how the presence of a specific protein called IL-22BP affects the composition of the gut microbiota and the body’s response to bacterial infection.
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NewsPhage-derived enzyme targets biofilms to mitigate acute graft-versus-host disease
Scientists investigating acute graft-versus-host disease probe gut microbiome to detect presence of a bacteriophage-derived enzyme known as endolysin, exhibiting potent antibacterial activity specifically targeting E. faecalis.
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NewsScientists isolate amylase enzyme produced by indigenous bacteria from sugar factory waste
Experts in wastewater processing and treatment have isolated amylase-producing bacteria from the liquid waste of sugar local factories and optimized the production of the amylase enzyme.
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NewsDegradation of cell wall key in the spread of resistance
A new study shows how an enzyme breaks down the bacteria’s protective outer layer, the cell wall, and thus facilitates the transfer of genes for resistance to antibiotics.
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NewsWater-soluble version of bacterial enzyme may help researchers develop new antibiotics
Researchers created a water-soluble version of an important bacterial enzyme, which can now be used in drug screens to identify new antibiotics.
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NewsScientists unveil hepatitis B virus core protein as a Rab-GAP suppressor driving liver disease progression
In liver cells under oxidative stress, HBV core protein (HBc) perturbs mitochondrial dynamics and prevents cellular recycling of damaged mitochondria, thereby driving liver disease progression, a new study finds.