All Proteomics & Enzymology articles
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NewsScientists research potential anti-ulcer vaccine targeting Helicobacter pylori
Scientists are on the way to finding a vaccine to fight off the Helicobacter pylori bacterium, possibly preventing stomach ulcers and lowering the risk for stomach cancer. They used immunoinformatics to scan its genetic makeup and predict which parts can trigger a strong immune response.
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NewsExpanding the genetic toolkit: nitrogen-response promoters developed for Bacillus licheniformis
Promoters are crucial expression elements in synthetic biology, and Bacillus licheniformis serves as an excellent chassis cell for industrial production, but is restricted by a lack of nitrogen source-responsive promoters.
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NewsResearchers map correlations between gene variants and proteomes
Scientists have discovered a way to predict the effects of numerous mutations in yeast - a valuable tool for better understanding molecular mechanisms. Key to this discovery was a detailed analysis of the proteome – the collection of all proteins inside a cell.
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NewsParasite paparazzi take millions of photos of secret malaria proteins
Using millions of microscope images magnified up to 130,000 times, researchers have unraveled the structure of two key proteins in the malaria parasite. With this knowledge, scientists are developing new vaccines that block the transmission of parasites via mosquitoes.
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NewsMicrobiome and nanoparticle discoveries hold promise for treating gut pain
In an effort to develop targeted treatments for gut pain, scientists have discovered a new enzyme in gut bacteria and are using nanoparticles to deliver drugs inside cells. PAR2, a receptor involved in pain signaling, is activated by certain enzymes called proteases.
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NewsProfessor awarded $3.9 million to fight deadly parasites that threaten children and immunocompromised adults
A multi-institutional team will develop effective drugs that are urgently needed to manage cryptosporidiosis in young children, immunocompromised adults and as a countermeasure to epidemic outbreaks.
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NewsStudy shows mucus contains molecules that block Salmonella infection
Researchers have identified mucins that defend against Salmonella and other bacteria that cause diarrhea. They now hope to mimic this defense system to create synthetic mucins that could help prevent or treat illness in soldiers or other people at risk of exposure to Salmonella.
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NewsNew mechanisms for bacterial motility and DNA transfer between bacteria decoded
Scientists have discovered a new family of signaling proteins, widespread in the bacterial kingdom and contributing to regulating bacterial motility and DNA uptake mechanisms.
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NewsHeadspace invaders: How mosquito-borne viruses breach the brain’s defenses
Using a stem cell-based model of the human blood-brain barrier, researchers compared two closely related Sindbis virus strains — one brain-invading and one not — and found that small changes in viral surface proteins called glycoproteins dictate whether the virus can cross.
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NewsStudy reveals how tick-borne encephalitis virus enters cells
The protein on human cells that tick-borne encephalitis virus (TBEV) uses for infection has now been identified—a major step toward understanding how TBEV causes neurological disease and for developing antiviral drugs.
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NewsHow viruses build perfectly symmetrical protective shells
Researchers used a new simulation framework to capture key biological factors like protein diffusion, genome flexibility, and shape-shifting behavior to model how viral proteins self-assemble into symmetric shells.
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NewsAI uncovers hidden rules of some of nature’s toughest protein bonds
Scientists have shown how artificial intelligence can reveal the hidden rules of one of biology’s strangest phenomena: catch-bonds – molecular interactions that get stronger when pulled. Their findings shed light on how bacteria cling to surfaces, how tissues resist tearing, and how new biomaterials might be designed to harness force.
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NewsStudy shows not all dietary proteins are digested the same way
As protein-rich diets become increasingly popular, a new study suggests that categorizing dietary proteins as either animal- or plant-based fails to effectively capture the source-specific differences in their composition, digestive efficiency and accessibility to the gut microbiota.
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NewsA survival kit for smallpox viruses
Scientists have discovered a previously unknown type of assembly chaperone during their analysis of poxviruses, and they have decoded its function in full detail. This is the first known chaperone that is not formed by a protein but by a nucleic acid — specifically RNA.
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NewsResearchers map key human proteins that power coronavirus replication, pointing to new treatment strategies
Scientists have pinpointed dozens of human proteins that SARS-CoV-2 needs to complete its full life cycle, from entering a cell to replicating and releasing new viral particles.
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NewsThe cling of doom: How staph bacteria latch onto human skin
Scientists have discovered the strongest natural protein bond ever recorded, explaining how Staphylococcus aureus clings so tightly to human skin and pointing to new ways to fight antibiotic resistance.
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NewsHow plants rot: New method decodes hidden decomposers of wood and leaves
Researchers have developed a new method to identify the molecular tools that different species use to decompose dead plant material. Their analysis of over 18,000 species found that some invertebrates also evidently have a whole range of such tools at their disposal.
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NewsAncient viruses in human genomes offer new avenue for stopping cancers, autoimmune diseases, and more
Researchers have revealed the first three-dimensional structure of a protein from an ancient human endogenous retrovirus (HERV) found within the human genome.
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NewsBioscientist wins NSF CAREER Award to investigate bacterial toxins, expand inclusion in STEM
Marcos de Moraes has received support to study the molecular mechanisms and evolutionary roles of bacterial toxins known as deaminases, as well as an educational outreach effort aimed at making biosciences open to all, including differently abled persons.
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NewsSmall protein, big impact: Insights into how bacteria stabilize a key outer membrane complex
Researchers reveal that a remarkably small protein is essential for the maturation of a component of the lipopolysaccharide transport system.