All Proteomics & Enzymology articles – Page 2
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New tool reveals how malaria sticks to red blood vessels
Scientists have unveiled a new tool for studying the highly variable traits that allow malaria parasites to stick to red blood cells and evade the immune system.
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Scientists uncover new mechanism in bacterial DNA enzyme opening pathways for antibiotic development
Researchers have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic target. This enzyme, present in bacteria but absent in humans, plays a crucial role in supercoiling DNA, a necessary process for bacterial survival.
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Scientists discover how innate immunity envelops bacteria
The human protein GBP1 fights against bacteria and parasites by enveloping them in a protein coat, but how the substance manages to do this has remained unknown until now. Researchers have unravelled how this protein operates.
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Selfishness mechanism points way to optimizing inhibitors that fight antibiotic resistance
Resistance can be fought by targeting bacteria that are ’selfish’ with their antibiotic resistance tools, according to a new study.
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Scientists discover viral trapdoor blocking HIV and herpes
A group of researchers led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center for Medical Biotechnology discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them ...
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Scientists engineer new enzyme to produce synthetic genetic material
Researchers have engineered an efficient new enzyme that can produce a synthetic genetic material called threose nucleic acid. The ability to synthesize artificial chains of TNA advances the discovery of therapeutic options to treat cancer and other diseases.
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Study finds persistent infection could explain long COVID in some people
Researchers found people with wide-ranging long COVID symptoms were twice as likely to have SARS-CoV-2 proteins in their blood, compared to those without long COVID symptoms.
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Scientists develop enzyme complex to find Achilles heel of protozoan parasite
In an effort to find a new weak spot of the protozoan parasite Trichomonas vaginalis, researchers have succeeded in preparing a key enzyme complex – the proteasome.
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Scientists unravel the secrets of the spiral bacterium
A team of researchers has discovered the mechanism that determines the spiral shape of Rhodospirillum, shedding new light on the link between cell shape and fitness.
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Plastic-eating enzyme identified in wastewater microbes
Plastic pollution is everywhere, and a good amount of it is composed of polyethylene terephthalate (PET, ♳). This polymer is used to make bottles, containers and even clothing. Now, researchers report in ACS’s Environmental Science & Technology that they have discovered an enzyme that breaks apart PET ...
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Filament structure activates and regulates CRISPR-Cas ‘protein scissors’
Researchers have revealed the structure of the CRISPR-Cas ‘protein scissors’ found in bacteria and provided mechanistic details on how they function.
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Peptide acts as molecular shield to prevent SARS-CoV-2 from infecting cells
The synthetic peptide was inspired by ACE2, the protein to which the virus that causes COVID-19 binds to invade human cells. The results point to a route for the development of novel antivirals.
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Study unveals a novel protective mechanism in bacterial cell wall
Researchers from Umeå University, Sweden, and Cornell University, USA, have discovered a widespread mechanism in bacteria that enhances the bacteria’s defense against environmental threats. Source: Umeå University Sara Hernandez and Laura Alvarez, two of the researchers behind the study in the lab. The discovery, which may be ...
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Bacterial ‘flipping’ allows genes to assume different forms
A new study has shown that inversions, which cause a physical flip of a segment of DNA and change an organism’s genetic identity, can occur within a single gene, challenging a central dogma of biology — that one gene can code for only one protein.
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Scientist devises test feed for fungal ‘micro-machine’ that breaks down wood
Researchers investigating a molecular machine found in fungi that decomposes wood into its basic components have come up with a test feed that allows them to observe its close-to-natural action, opening the door to putting it to industrial application.
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Scientists unveil how the oceans’ most abundant bacteria impact global nutrient flows
A new paper has revealed how key bacterial proteins contribute to global carbon, sulfur and other nutrient cycles.
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Extreme microbe reveals how life’s building blocks adapt to high pressure
An AI tool has helped scientists discover how the proteins of a heat-loving microbe respond to the crushing conditions of the planet’s deepest ocean trenches, offering new insights into how building blocks of life might have evolved under early Earth conditions.
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Scientists close in on mystery of deadly Hep C virus
A new study by a cross-disciplinary research team has identified the protein complex at the surface of the hepatitis C virus that enables it to bind to human cells, opening a pathway to vaccine candidates that can prevent the virus from infecting the cells.
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Study of mosquito spit could lead to therapies for viruses like West Nile and yellow fever
Researchers are analyzing samples of noninfectious mosquito saliva in the fight against arboviruses — viruses spread by arthropods like mosquitoes.
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Surprise find in study of environmental bacteria could advance search for better antibiotics
In what they labeled a “surprising” finding, researchers studying bacteria from freshwater lakes and soil say they have determined a protein’s essential role in maintaining the germ’s shape.