All Research News articles – Page 21
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NewsGut bacteria molecule boosts lung cancer treatment response
Researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.
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NewsPlant discovery could lead to new ways of producing medicines
Scientists studying a plant called Flueggea suffruticosa, which produces a particularly powerful alkaloid known as securinine, investigated how this chemical is made - and discovered that the process is driven by a gene that looks more like it comes from bacteria than from a plant.
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NewsNew study explores therapeutic potential of CRISPRCas3 genome-editing system
Scientists working on the genetic disease transthyretin amyloidosis evaluated the efficacy of the CRISPR–Cas3 system in safely achieving a permanent reduction of transthyretin (TTR) production through genome editing of the TTR gene.
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NewsSame moves, different terrain: How bacteria navigate complex environments without changing their playbook
New research shows that a diverse group of bacteria has learned how to use the same basic movements to move through a wide range of environments no matter how complex, from unconstrained fluids to densely packed soil and tissues.
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NewsMaternal microbiome compound may hold key to preventing liver disease
Children born to mothers who consume a high-fat, high-sugar diet during pregnancy and breastfeeding face a higher risk of developing fatty liver disease later in life. New research suggests that risk may be reduced by supplementing with a naturally occurring compound produced by healthy gut bacteria.
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NewsA new study reveals how cholera virulence is activated
A new study provides a long-sought structural explanation of the regulatory cascade that allows Vibrio cholerae to colonize the human gut and produce the cholera toxin that causes life-threatening diarrhea.
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NewsTB and HIV treatments are not enough for a full recovery
Existing treatments control TB and HIV, but the immune system does not revert to normal, helping explain why people living with HIV remain susceptible to infections and underscoring the need for immunotherapies.
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NewsAboard the International Space Station, viruses and bacteria show atypical interplay
In a new study, terrestrial bacteria-infecting viruses were still able to infect their E. coli hosts in near-weightless “microgravity” conditions aboard the International Space Station, but the dynamics of virus-bacteria interactions differed from those observed on Earth.
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NewsWhy don’t antibiotic-making bacteria self-destruct?
Scientists discovered a promising new antibiotic in a soil sample. The molecule, lariocidin, is produced by the microbe Paenibacillus and shows broad activity against pathogenic bacteria. Now, the researchers report how Paenibacillus avoids harm by its own antibiotic.
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NewsScientists observe infections by cancer-causing retroviruses in koalas as they occur
Scientists analysed the ongoing colonization by two retroviruses of the germline of koalas and resulting deaths from cancer in multi-generational pedigrees of over 100 koalas in US and European zoos. They calculated genetic risk scores (GRS) that can help guide koala breeding programs.
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NewsWhen a virus releases the immune brake: New evidence on the onset of multiple sclerosis
A study investigating the links between Epstein-Barr virus and multiple sclerosis shows that EBV can interfere with the control of B cells. One viral protein mimics a crucial “approval” signal that B cells usually require from other immune cells. Self-reactive B cells can then survive even when they should be shut down.
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NewsResearch reveals hidden diversity of E. coli driving diabetic foot infections
New research has shed light on the diversity and characteristics of E. coli strains that drive diabetic foot infections, providing the first comprehensive genomic characterisation of E. coli strains isolated directly from diabetic foot ulcers across multiple continents.
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NewsNew mechanism links Epstein-Barr virus to MS
Scientists investigating the links between the Epstein-Barr virus and multiple sclerosis show that when the immune system fights EBV, certain T cells – which normally attack the virus – can also react to a protein in the brain called Anoctamin-2 (ANO2), a phenomenon called molecular mimicry.
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NewsNot only toxic but also a nutrient: guanidine as a nitrogen source
Cyanobacteria are key ecological players of global carbon and nitrogen cycles. They are also becoming increasingly important for carbon-neutral biotechnology. They could serve as green cell factories for a light-driven and sustainable production of chemicals and fuels – a central pillar of the sustainable bioeconomy. Source: André Künzelmann/UFZ ...
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NewsGenetic risk factor and viral infection jointly contribute to MS
One of the leading triggers for multiple sclerosis (MS) is an infection with the Epstein-Barr virus. However, certain gene variants also play an important role. Researchers have shown that it is the molecular interaction between environmental and genetic risk factors that ultimately triggers the disease.
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NewsRare microbial wrinkle structures - signs of ancient life - turn up in an unexpected place
Deep water sediment layers in the Dadès Valley in the Central High Atlas Mountains of Morocco have revealed rare microbial wrinkle structures formed far from sunlight.
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NewsFirst extensive study into marsupial gut microbiomes reveals new microbial species and antimicrobial resistance
New research provides the first metagenomic data for 13 marsupial species , including the red kangaroo and the common brushtail possum. They revealed that host family, animal location, and diet all contributed towards variance between different microbiomes.
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NewsA protein found in the GI tract can neutralize many bacteria
The mucosal surfaces that line the body are embedded with defensive molecules that help keep microbes from causing inflammation and infections. One of these molecules, intelectin-2, has broad-spectrum antimicrobial activity against bacteria found in the GI tract.
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NewsGut bacteria protect mice with influenza A from bacterial pneumonia, study finds
Select gut bacteria protect mice against post-influenza virus secondary bacterial pneumonia, according to a study which sought to define whether intestinal bacteria influenced some individuals’ vulnerability to secondary bacterial infections following primary respiratory viral infection.
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NewsCat disease challenges what scientists thought about coronaviruses
Researchers have uncovered new details about how a once-deadly coronavirus disease in cats spreads through the immune system. For years, the prevailing belief was that the virus behind feline infectious peritonitis infected just one type of immune cell.