All Research News articles – Page 24
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NewsRepurposed antibiotic shows promise against Central Nervous System Tuberculosis
Researchers at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have demonstrated that doxycycline, a commonly available and inexpensive antibiotic, can improve survival rates and neurological outcomes in Central Nervous System Tuberculosis (CNS-TB) in a preclinical non-human study. Published in the Journal of Neuroinflammation, the ...
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NewsGrassland degradation reshapes relationship between biodiversity and ecosystem multifunctionality
Grassland degradation fundamentally reshapes how biodiversity supports ecosystem multifunctionality, shifting it from being plant-dominated to being mediated by soil microbes, according to a new study of alpine grassland on the Tibetan Plateau.
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NewsBlood-based immunological signatures for extrapulmonary tuberculosis decoded
Scientists have deciphered the immunological properties of extrapulmonary tuberculosis (EPTB) in the blood of affected patients. The results may help to develop new targeted treatments and tests for this important disease.
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NewsFlu vaccine providing important protection despite new subclade
Children and adults across England are receiving strong protection from this year’s flu vaccine, despite the emergence of a new subclade driving an unusually early flu season.
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NewsScientists reveal how cyanobacteria use ’sunscreen’ to adapt to climate
Using single particle spectroscopy, researchers revealed insights into how different types of photosynthetic bacteria can use a shared mechanism to protect themselves from too much sunlight.
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NewsHow life first got moving: nature’s motor from billions of years ago
Research has cast light on the evolutionary origins of one of nature’s first motors, which developed 3.5 billion to 4 billion years ago to propel bacteria. Scientists have created the most comprehensive picture yet of the evolution of bacterial stators.
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NewsScientists uncover global patterns and drivers of orchid mycorrhizal interactions
A global meta-analysis of orchid-fungal associations leads to a general conclusion: an orchid’s fungal community is driven more strongly by its ecophysiology and biogeography than by its phylogeny.
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NewsCould tiny airborne plastics help viruses spread? Scientists warn of a hidden infection risk
While plastics are already recognized as a global environmental threat, a new commentary highlights that their microscopic airborne forms could also play a hidden role in human infection.
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NewsNew drug target identified in fight against resistant infections
Researchers have identified new drug targets within a special repair system possessed by certain bacteria, known as Rtc, which enables them to counteract the effects of these antibiotics.
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NewsHow are metabolism and cell growth connected? — A mystery over 180 years old
A research team has identified a novel principle in biology that mathematically explains why the growth of organisms slows as nutrients become more abundant—a phenomenon known as “the law of diminishing returns.”
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NewsResearchers reveal novel mechanisms for decoding bacterial frequency modulation in signal processing
A study reveals the fundamental physical principles underlying bacterial FM signal processing, and demonstrated that FM decoding mechanisms enable bacteria to increase information entropy by approximately 2 bits compared to traditional AM in three-gene regulatory systems.
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NewsSingle-cell insights reveal how HPV status reshapes penile tumor immunity
A study found that HPV-positive tumors in penile squamous cell carcinoma cases contained fewer proliferative macrophages and less exhausted CD8+ T cells, along with stronger chemokine signaling, revealing distinct immune remodeling associated with HPV infection.
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NewsGut microbiota: implications in pathogenesis and potential therapeutic target in primary biliary cholangitis
A new review synthesizes current evidence on gut microbiota dysbiosis in PBC, elucidates its pathogenic mechanisms, and explores its potential as both a diagnostic biomarker and a novel therapeutic target.
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NewsSecrets of microbial motion: How bacteria swash, glide and shift gears to survive
Two new studies reveal surprising ways microbes move, with implications for human health and disease. The first shows that salmonella and E. coli can ’swash’ across moist surfaces even when their flagella are disabled, while the second probes the T9SS gearbox in flavobacteria.
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NewsHeatproof microbes reveal molecular secrets of nature’s hottest recycling system
This study reveals how thermophilic bacterial communities withstand temperatures of up to 87°C by remodeling their molecular machinery. Scientists uncovered a heat-defense network centered on heat shock proteins that refold damaged enzymes and preserve protein structure.
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NewsHidden HPV-linked cell type may drive early cervical cancer, scientists report
A new study identifies tumor-promoting keratinocytes linked to HPV infection and poor prognosis. Scientists employed single-cell RNA sequencing (scRNA-seq) and multiplex immunohistochemistry (mIHC) to delineate the molecular landscape of early-stage CESC.
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NewsNewly discovered host mechanism in coronaviruses
A previously unknown cellular mechanism crucial to the replication of coronaviruses has been identified: c-Jun N-terminal kinase (JNK) is activated during infection with human coronavirus HCoV-229E and mediates the phosphorylation of the viral nucleocapsid (N) protein.
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NewsFirst detection of zoonotic Rickettsia species in dog ticks from Malawi reveals potential public health risk
An international research team has reported the first molecular detection of Rickettsia bacteria in ticks collected from domestic dogs in Malawi, addressing a significant knowledge gap in understanding tick-borne disease risks in southeastern Africa.
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NewsCOVID-19 vaccination lowers long COVID risk in adolescents
Adolescents who were vaccinated against COVID-19 were less likely to develop long COVID after their first SARS-CoV-2 infection than unvaccinated peers, finds a new study.
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NewsNew study shows invasive Group A Streptococcus outcomes shaped by treatment strategies, not species lineage
Researchers highlight the role of early clindamycin prescription in improving the recovery rate of patients with invasive Group A Streptococcus infections in a study that examined the evolving epidemiology of such infections.