All Research News articles – Page 16
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Research opens up new avenue for tuberculosis drug discovery
Researchers studied an enzyme from the TB bacterium called alpha-methylacyl-CoA racemase (MCR) which helps the bacterium use cholesterol as an energy source. Blocking this enzyme would therefore starve the bacterium of a major food source, helping to treat TB infections.
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Study yields new insights into infection strategy of Pseudomonas aeruginosa
Scientists have uncovered a previously unknown trick used by Pseudomonas aeruginosa - the bacterium can functionally organize itself in diverse ways within a population of identical clones, as if it were not just one germ, but many at once. A mechanism of epigenetic memory preserves the activity of certain genes across generations.
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New immunotherapy strategy targets difficult-to-treat brain tumors with gut microbiota
Researchers have demonstrated a new therapeutic strategy that can enhance the efficacy of immunotherapy for brain tumors by utilizing gut microbes and their metabolites. This also opens up possibilities for developing microbiome-based immunotherapy supplements in the future.
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Seasonal allergies caused by fungal spores now start three weeks earlier under climate change
Researchers have found that, on average, spore allergy season in the US was kicking off 22 days earlier in 2022 than it had been in 2003.
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New collaboration harnesses COVID methods to combat multi-billion threat to UK forests
Harnessing methods used to successfully predict and understand the spread of COVID-19 during the pandemic, a new project aims to combat the impact of forest diseases that can cost the UK economy billions.
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Prebiotics might be a factor in preventing or treating issues caused by low brain GABA
Dietary prebiotics may induce an increase in brain GABA levels through the regulation of gut microbiota, which can be a major point for reducing or even treating these occurrences of certain neurological diseases in individuals.
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Scientists target ‘molecular machine’ in the war against antimicrobial resistance
The ‘molecular machine’ flagellum is essential for bacteria to cause infection, allowing bacteria to ‘swim’ around the bloodstream until finding something to infect. But it could also be a target for antibiotics.
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Novel flu vaccine adjuvant improves protection against influenza viruses, study finds
Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus challenges when combined with a mucosal adjuvant that enhances the body’s immune response, according to a study.
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Pair of malaria parasite proteins could lead to targeted therapies
Scientists have made an advance in the basic understanding of Plasmodium falciparum, the parasite responsible for the deadliest form of human malaria, that could make novel, highly targeted anti-malarial therapies possible.
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Research suppresses coronavirus by targeting Mac1
A new study details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or the “macrodomain,” found in all coronaviruses such as SARS-CoV-2 and MERS-CoV.
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New ECDC weekly reports and guidance to tackle mosquito-borne diseases across Europe
As Europe enters this year’s mosquito season, ECDC has launched a new series of weekly epidemiological surveillance updates and public health guidance on mosquito-borne diseases.
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New viruses discovered in bat kidneys in Yunnan province
The viruses, as well as new bacterial species and a new parasite, were discovered in bats inhabiting orchards near villages in southwestern China, raising concerns about transmission to livestock or humans.
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Antibiotics are failing in many countries in Africa, new study reveals
The largest retrospective study on resistance to antibiotics in Africa highlights the need for major investments to enhance laboratory capabilities and healthcare access.
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Airborne fungal spores may help predict COVID-19 & flu surges
Monitoring fungal spores in the outdoor air can predict surges in flu and COVID-19 infections, especially during the fall, according to a new study
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With AI, researchers find increasing immune evasion in H5N1
A new analysis suggests that the H5N1 avian influenza virus is evolving clever strategies. Using artificial intelligence tools, researchers analyzed thousands of viral proteins and found that their bonds to protective antibodies have weakened over time.
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Pandora’s microbes – The battle for iron in the lungs
Newly discovered natural compounds from the little studied Pandoraea bacterium influence the lung microbiome by competing for iron.
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Tracking microbial rhythms reveals new target for treating metabolic diseases
Researchers harness the benefits of time-restricted feeding on the gut microbiome — with the ultimate goal of developing new therapies for obesity, diabetes and related diseases.
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Supercharged HIV vaccine could offer strong protection with just one dose
Researchers have shown that they can generate a strong immune response to HIV with just one vaccine dose, by adding two powerful adjuvants — materials that help stimulate the immune system.
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How a common brain parasite disrupts neural communication
Scientists reveal how the Toxoplasma parasite can significantly disrupt brain function, even when it infects only a small number of neurons. The team found the parasite interferes with essential communication between brain cells.
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Herpes virus plays interior designer with human DNA
Researchers have discovered the cold sore virus reshapes the human genome’s architecture, rearranging its shape in three-dimensional space so that HSV-1 can access host genes most useful for its ability to reproduce.