All ulcerative colitis articles
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NewsEpstein-Barr virus worsens ulcerative colitis by triggering macrophage pyroptosis through glycolysis
The study shows that EBV infection activates pyroptosis in intestinal macrophages by upregulating glycolysis. This process leads to the release of pro-inflammatory cytokines, which further damage the intestinal barrier and worsen colitis symptoms.
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NewsGut bacterium IDed as key player in healing the colon
Researchers have identified Clostridium scindens, a bacterium that converts primary bile acids into 7α-dehydroxylated bile acids, as a key player in gut healing. Supplementing the gut with this bacterium could improve recovery from colonic injury.
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Newsβ-ionone shows promise in preventing ulcerative colitis through gut barrier protection and microbiota regulation
New research demonstrates that β-ionone can alleviate ulcerative colitis symptoms in mice by protecting the gut barrier and restoring the gut microbiota, offering hope for future dietary supplements or therapeutics aimed at managing UC.
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NewsNew evidence links gut microbiome to chronic disease outcomes
A new review consolidates recent findings that demonstrate a causal role for the gut microbiome in the progression of multiple diseases, ranging from gastrointestinal conditions to immune-related and psychiatric disorders.
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News$5.6 million grant awarded to target treatments for IBS, Crohn’s and Ulcerative colitis
An “out-of-the-box” study has been awarded a $5.6 million NIH grant to target treatments for IBS, Crohn’s, Ulcerative Colitis and more.
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NewsResearchers develop probiotic to ameliorate ulcerative colitis
Researchers have developed a probiotic-based therapeutic that synergistically restores intestinal redox and microbiota homeostasis. It relieved inflammation and reduced colonic damage in mouse and non-human primate (NHP) models of colitis.
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NewsGut bacteria and inflammatory bowel disease: a new frontier in treatment
A new review highlights the therapeutic potential of various prebiotics derived from different food sources for manipulating gut bacteria.
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NewsStudy reveals possible triggers for inflammatory bowel disease
A new study finds a complex interplay between diet, genes, and the gut microbiota that could explain why IBD develops.
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NewsOral lipid nanoparticle drug can prevent development of colitis-associated cancer
An oral lipid nanoparticle drug prevents tumor development in mice, suggesting this is a promising drug formulation for preventing colitis-associated cancer, according to a study led by researchers in the Institute for Biomedical Sciences at Georgia State University. The findings published in the journal Pharmaceutics report the ...
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NewsWidely consumed vegetable oil leads to an unhealthy gut
Researchers examined the gut of mice that were consistently fed a diet high in soybean oil for up to 24 weeks in the lab, finding beneficial bacteria decreased and harmful bacteria increased — conditions that can lead to colitis.
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NewsSleep supplement impairs action of gut microbiota
Despite its antioxidant effects and role in regulating sleep cycles, tests show melatonin can worsen inflammation of the intestine and impair the action of gut microbiota.
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NewsStool transplants more effective than antibiotics for treating recurring, life-threatening gut infections
A new Cochrane Review has found that, compared with standard antibiotic treatment, stool transplantation can increase the number of people recovering from Clostridioides difficile infection from 40% to 77%.
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NewsProbiotic ‘backpacks’ could treat inflammatory bowel diseases
Researchers have devised specialised nano-particles that can neutralise molecules linked to inflammatory bowel disease (IBD), and can be attached to beneficial probiotic bacteria targeting the gut.
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NewsAlterations to gut mucus may trigger ulcerative colitis
Research published in the Proceedings of the National Academy of Sciences proposes a set of conditions that could act as a starting point for the development of ulcerative colitis.