All USA & Canada articles – Page 20
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Placebo-testing vaccines is unethical, ‘a waste of time and money,’ expert says
The proposal to require that all new vaccines undergo safety testing in placebo-controlled trials is ethically problematic and will slow testing down for no good reason, warn scientists.
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Antibodies that recognize lipids: A new path for HIV vaccines and autoimmune disease treatments
Scientists have used computer modeling to illustrate how a specific class of antibodies actually use lipids to recognize the HIV virus. The work highlights antibody features that could help people design better vaccines for HIV and autoimmune diseases.
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Scientists uncover the link between ‘good’ gut bacteria and rheumatoid arthritis
After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown how activity of “good” microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.
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$2.7 million NIH grant to fund first comprehensive syphilis test
With a four-year, $2.7 million grant from NIAID, researchers aim to develop a one-step confirmatory laboratory test that can definitively diagnose active syphilis infection within 10 minutes.
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Monoclonal antibody nirsevimab provides strong protection against severe RSV in infants
Nirsevimab, a monoclonal antibody, is highly effective in real-world conditions at preventing severe respiratory syncytial virus (RSV) infections in infants, suggests a meta-analysis.
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A digestive ‘treasure chest’ shows promise for targeted drug treatment in the gut
A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments.
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Designer microbe shows promise for reducing mercury absorption from seafood
Scientists who inserted DNA-encoding methylmercury detoxification enzymes into the genome of an abundant human gut bacterium found it detoxified methylmercury in the gut of mice and dramatically reduced the amount that reached other tissues.
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Study of facial bacteria could lead to probiotics that promote healthy skin
Researchers have revealed the dynamics of interactions between two dominant skin bacterial species in more detail than previously possible, shedding light on when and how new bacterial strains emerge on the skin of the face.
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Bacterial villain behind Lake Erie’s ‘potent toxin’ unveiled by study
In Lake Erie, cyanobacteria can proliferate out of control, creating algal blooms that produce toxins that can harm wildlife and human health. Researchers have IDed the organism responsible for the toxins: a cyanobacteria called Dolichospermum.
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Protein sources change the gut microbiome – some drastically
A new study shows that protein sources in an animal’s diet can have major effects on both the population and function of the gut microbiome. The two largest effects of dietary protein were on amino acid metabolism and complex sugar degradation.
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Bacteria deployed as living test tubes to study human gene mutations
Bioengineers have developed a new simple approach to rapidly check on human gene changes and also screen chemicals as potential drugs by turning everyday bacteria into living test tubes.
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New AI technique can uncover antiviral compounds using limited data
Artificial intelligence algorithms have been combined with traditional laboratory methods to uncover promising drug leads against human enterovirus 71 (EV71), the pathogen behind most cases of hand, foot and mouth disease.
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New study reveals emerging cases of babesiosis in Mid-Atlantic region
A newly published study provides critical insights into the emergence of babesiosis in the Mid-Atlantic region, documenting human cases and the presence of Babesia microti in local tick populations.
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Pediatric investigation review discusses the challenges, innovations, and future directions in dengue vaccine development
A new review discusses the current status and implications of dengue vaccines like CYD-TDV, TAK-003, and Butantan-DV while exploring the challenges in Dengue vaccine development like ADE, and proposes future directions in this field.
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Broader antibiotic use could change the course of cholera outbreaks, research suggests
Disease modeling research suggests that, for some cholera outbreaks, prescribing antibiotics more aggressively could slow or stop the spread of the disease and even reduce the likelihood of antibiotic resistance.
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Fungi dwelling on human skin may provide new antibiotics
Researchers have uncovered a molecule produced by yeast living on human skin that showed potent antimicrobial properties against a pathogen responsible for a half-million hospitalizations annually in the United States.
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Now is the time to strengthen infection prevention and control (IPC) programs in healthcare facilities
A joint position paper urges United States healthcare facilities to elevate the standards and effectiveness of their Infection Prevention and Control (IPC) programs.
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How math helps to protect crops from invasive disease
New research demonstrates how mathematical modeling can predict outbreaks of toxic fungi in Texas corn crops—offering a potential lifeline to farmers facing billions in harvest losses.
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Measles may be making a comeback in the US, research finds
If immunization rates drop further over a prolonged period of time, measles and even other wiped-out diseases — such as rubella and polio — could one day make a comeback in the United States, according to a new study.
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Bacteria’s mysterious viruses can fan flames of antibiotic damage, according to new model
Researchers built a model that allows them to diminish phage communities from a mouse gut microbiome — and then bring them back — without affecting the bacteria. A test run found evidence that phages may increase gut bacteria’s sensitivity to antibiotics.