All Zhejiang University articles
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NewsEngineered microbial communities offer a faster route to removing herbicide residues from soil
A new review highlights how carefully designed teams of microorganisms could offer a more effective way to break down herbicide contaminants than relying on individual microbial strains.
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NewsNew evolution platform creates tougher yeast for sustainable biomanufacturing
Researchers have now developed a powerful new tool that accelerates microbial evolution. Their study introduces RAMPAGE, a programmable system that continuously generates genetic diversity across the genome of the industrial yeast P. pastoris.
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NewsSelf-renewing bacteria offer new hope for heavy metal cleanup
Scientists have revealed a powerful bacterial defense strategy against Cd toxicity. The team found that Stenotrophomonas sp. H225 sheds Cd-laden cell wall fragments and rebuilds new protective layers through a process involving the mtgA gene.
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NewsExtracellular vesicle RNAs offer new hope for diagnosing and treating chronic inflammatory bowel disease
Extracellular vesicle-associated RNAs can serve as non-invasive biomarkers for early inflammatory bowel disease detection and disease monitoring, and also hold great potential as targets for next-generation targeted therapies, according to a new review.
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NewsBrewing a rare medicine: yeast engineered to produce a valuable astragalus isoflavonoid
By reconstructing the complete biosynthetic pathway inside Saccharomyces cerevisiae and systematically removing metabolic bottlenecks, researchers created the first yeast platform capable of producing calycosin-7-glucoside from simple carbon sources.
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NewsEngineered yeast delivers record levels of animal-free chondroitin sulfate
A new study establishes a robust yeast-based platform that overcomes the long-standing trade-off between yield and sulfation, enabling sustainable, high-level production of high-quality chondroitin sulfate without reliance on animal sources.
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NewsHow reactive oxygen species target viruses differently: new clues for safer water disinfection
A new study systematically explored how reactive oxygen species (ROS) inactivate viruses with distinct structures. The results revealed clear heterogeneity: enveloped RNA viruses were most susceptible to oxidation, while double-stranded DNA viruses showed strong resistance.
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NewsScientists reveal molecular cause behind “stuck” beer fermentation
Premature yeast flocculation (PYF) is a persistent issue in beer brewing, where yeast settles too early during fermentation. New research identifies multiple differential metabolites and confirmed galangin as a key factor that promotes early yeast aggregation.
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NewsFertilizer boosts soil’s ability to lock away carbon
The 180-year experiment at Rothamsted — the world’s longest-running agricultural trial — has revealed that long-term application of nitrogen and phosphorus fertilisers can significantly increase the amount of carbon stored in farmland soils, helping to mitigate climate change.
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NewsStructural diversity of pyripyropenes via biosynthetic gene cluster design and heterologous expression in Aspergillus nidulans
Researchers have designed a reconstituted biosynthetic gene cluster (BGC) for producing structurally diversified deacetylated pyripyropenes, using the native pyripyropene A BGC from the wild-type strain Aspergillus fumigatus Af 293 as a template.
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NewsAI accelerates design of next-generation antimicrobial peptides with precision targeting
A new opinion article highlights how artificial intelligence (AI), nanotechnology, and interdisciplinary research are revolutionizing AMP design and application, outlining recent breakthroughs in designing, optimizing, and delivering AMPs with enhanced efficacy and safety.
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NewsNew review unveils breakthroughs in soil nitrogen cycle research from microbial pathways to global sustainability
A comprehensive review highlights significant advances in understanding the soil nitrogen cycle, emphasizing the critical role of microbial processes and innovative technologies in achieving global nitrogen sustainability.
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NewsCircadian rhythms in tea plant microbiomes shed light on nutrient cycling
A groundbreaking study has uncovered a fascinating connection between the circadian rhythms of tea plants and the microbial communities in their rhizosphere, providing new insights into nutrient cycling.
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NewsNew tool enables a more complete and rapid decoding of the language of algal gene expression
A new method that research teams can use to measure and compare different forms of proteins and protein complexes helped reveal a previously unseen molecular signature of how algal genomes are controlled during the cell cycle.
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NewsOrigami paper sensors could help early detection of infectious diseases in low-cost test
Researchers have developed an innovative new method for identifying biomarkers in wastewater using origami-paper sensors, enabling the tracking of infectious diseases using the camera in a mobile phone.
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NewsScientists solve mystery of bacterial scavenging machinery
Scientists investigated how the oleate shuttle from FakB2 to FakA kinase works in the Fak system, which is exploited by the zoonotic pathogen Streptococcus suis (S. suis) pathogen to scavenge exogenous fatty acid (eFA).
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NewsRoot microbiota fight back against leaf-mining flies
A pioneering study reveals how cowpea plants respond to leaf-mining fly attacks by altering their root-associated microbiota. Leafminer infestation changes the rhizosphere microbiome, enriching beneficial nitrogen-fixing bacteria.
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NewsFunctional predictability of universal gene circuits in diverse microbial hosts
By developing a quantitative framework to explore the universality and reliability of biological parts in non-model organisms, the team characterized universal genetic parts in four microbial hosts that can be used to build biological circuits in living cells.
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NewsEarly surveillance of rice bakanae disease using deep learning and hyperspectral imaging
Scientists have developed a fast and non-destructive early diagnosis method for rice bakanae diseases based on hyperspectral data.
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NewsLongitudinal gut fungal alterations and potential fungal biomarkers for the progression of primary liver disease
Scientists have found that during liver disease progression, the abundance of Chytridiomycota increased initially, but was later replaced by Ascomycota in HCC.