All Asia & Oceania articles – Page 2
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NewsScreening for putative essential genes in Brucella abortus strains A19 and S2308 using transposon mutagenesis
The categorization of functional genes in Brucella requires refinement. This knowledge gap was addressed by classifying gene essentiality through constructing a transposon mutant library. Mariner transposon mutant libraries were independently constructed for Brucella abortus A19 and S2308.
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NewsApilimod blocks hepatitis E virus entry by targeting PIKfyve
Hepatitis E virus (HEV) is a major cause of acute viral hepatitis, yet antiviral treatment remains largely limited to the off-label use of ribavirin. Seeking alternative treatments,scientists screened compounds that interfere with endocytic and endolysosomal pathways—the intracellular transport system used by HEV during cell entry.
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NewsHPV-driven cell death pathways offer new directions for cervical cancer treatment
A new review proposes that PCD in cervical cancer should be understood not as a series of isolated pathways, but as an interconnected regulatory network that governs both tumor behavior and therapeutic sensitivity.
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NewsDeep-sea corals in fossil fuel-producing region have distinct microbial communities
Researchers who carried out the first comprehensive study of the microbial communities living in symbiosis with deep-sea corals in one of Brazil’s most active oil- and gas-producing regions discovered that each species hosts a distinct, and sometimes highly specialised, community of microorganisms.
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NewsStudy reveals fungi as overlooked players in agricultural antibiotic resistance
Fungi may be helping antibiotic resistance genes survive during livestock manure composting. Researchers found that suppressing fungal activity weakened microbial networks and increased the removal of resistance genes, suggesting that fungi could play an overlooked role in the environmental spread of antimicrobial resistance.
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NewsMicrobes could become factories for the next generation of food ingredients
Precision fermentation is moving beyond niche ingredients towards a broader role in food production, from egg-white substitutes to proteins that mimic meat. Researchers argue that scaling the technology across both high-value and everyday ingredients could help make food production more sustainable and resilient.
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NewsHidden fungi may act as masterminds of the forest microbiome
Hidden beneath the forest floor, certain fungi may have an outsized influence on the microbial communities surrounding plant roots. By combining large-scale DNA data with ecological modelling, researchers identified endophytic fungi as potential keystone species capable of reshaping underground microbial networks.
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NewsOne Health initiative aims to build safer, more sustainable food systems
A new One Health initiative in Thailand is bringing together expertise across food safety, antimicrobial resistance, climate change and public health. The platform aims to turn scientific evidence into coordinated action across agrifood systems, with a strong focus on collaboration between researchers, government, industry and international partners.
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NewsLeaf spectra reveal hidden nitrogen-fixing nodules in soybean roots
Soybean roots may no longer need to be dug up to reveal how well they are forming nitrogen-fixing nodules. Researchers have shown that hyperspectral signals from leaves can predict below-ground nodule traits, offering a non-destructive way to track plant–microbe partnerships under drought and salt stress.
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NewsCommon cell-death inhibitor reveals an unexpected pathway in tuberculosis
A widely used cell-death inhibitor may be triggering macrophage death during mycobacterial infection through an unexpected off-target pathway. The findings reveal a caspase-8-independent route to necroptosis and could help explain how damaging necrotic granulomas form during tuberculosis.
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NewsGut microbiome may help explain why sleep improvement varies after hydrogen supplementation
Hiroshima University researchers investigated the effects of hydrogen supplementation on sleep quality in healthy human volunteers. While hydrogen supplementation had no significant effect compared to a placebo, individuals in the hydrogen-supplementation group reporting better sleep quality were discovered to have a lower abundance of hydrogen producing bacteria in their gut microbiome.
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NewsHow eggplants ‘farm’ their own microbiomes: Genetic secrets revealed
Eggplants appear to actively shape the microbial communities around their roots through their own genetics. A large global study has identified more than 1,200 genetic variants linked to key root microbes, revealing how crop evolution and domestication may have helped plants recruit beneficial microbial partners.
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NewsNew dosing data expands HIV treatment options for newborns
Newborns with HIV can now be treated with dolutegravir from the first days of life. An international clinical study identified a safe dosing regimen that produced drug levels comparable to those seen in older children and adults, helping support the FDA’s expanded approval.
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NewsNeedle-free approach could offer a new way to deliver mRNA vaccines
A needle-free mRNA vaccine delivered through the skin protected mice against both SARS-CoV-2 and influenza while causing less inflammation than lipid-based formulations. The approach uses a high-pressure liquid jet and a combination of two immune-boosting adjuvants to strengthen protection without relying on conventional mRNA carriers.
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NewsOne strain, two jobs: Bacillus amyloliquefaciens SQ1 degrades wheat straw and suppresses aflatoxin-producing Aspergillus flavus
Bacillus amyloliquefaciens SQ1SQ1 functions as a dual-purpose biocatalyst for wheat straw biomass, breaking down cellulose while inhibiting fungal growth, thereby enhancing straw biotransformation, mitigating mycotoxin risk and supporting early crop growth.
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NewsNew architecture for antifungal drug precisely combats fungal infections in mice without the usual toxicity
By applying a unique molecular “scaffold,” researchers have created a broad-spectrum antifungal drug that homes in on a key fungal compound without disrupting the host’s cholesterol – a frequent side effect of current therapies. The compound’s selectivity could help avoid the toxic side effects that have plagued antifungal therapy regimens for decades.
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NewsChildhood measles vaccination rates fall worldwide post COVID-19
Routine vaccine program disruptions and under-resourced health systems are driving a global decline in childhood measles vaccination rates post COVID-19, a study has found.
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NewsArmored cells: A mineral shell lets whole-cell biocatalysts run 14 cycles for greener nicotinic acid
Scientists aiming to use whole-cell biocatalysis to manufacture niacin engineered Corynebacterium glutamicum to express a mutant nitrilase from Pseudomonas putida and then encapsulated the whole cells in a biomimetic hybrid shell.
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NewsTargeting the gut-liver axis: New review explores microbial modulation to enhance immunotherapy in hepatocellular carcinoma
A review examines how gut microbiota and their metabolites reshape the hepatic immune microenvironment through the gut–liver axis, influence immune checkpoint inhibitor efficacy, and explore emerging combination strategies, including fecal microbiota transplantation, probiotics, engineered bacteria, and metabolite-based interventions.
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NewsNew hypothesis drills down into the contributions of phage receptor-binding proteins in recognising a bacterial cell
A new hypothesis reveals how different receptor-binding proteins may make distinct contributions when a bacteriophage recognizes a bacterial cell.