All Bioengineering articles
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NewsWith large DNA fragment assembly, scientists can design microbes that produce countless complex products
A review demonstrates that scientists can now reliably build and combine very large pieces of DNA, making it much easier to redesign microbes such as yeast and bacteria to act as efficient “cell factories.”
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NewsFrom gut to brain: scientists engineer bacteria to treat severe liver-related brain dysfunction
In vivo studies showed that programmable “living medicines” could reduce brain toxins and prevent neurological symptoms of hepatic encephalopathy, offering distinct advantages over a widely prescribed antibiotic.
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NewsA universal toolkit for editing bacterial DNA
A major collaboration involving nine labs has transferred a particularly useful DNA editing system from E. coli into 14 new species of bacteria, spanning three major branches of the bacterial family tree.
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NewsHow AI can help us count the ‘good’ viruses used in biopharmaceuticals
Researchers have developed a new methodology that uses artificial intelligence (AI) tools to identify and count target viruses more efficiently than previous techniques. The new approach can be used in applications such as pharmaceutical biomanufacturing.
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NewsResearchers fight oral cancer with bioengineered chewing gum
Research shows that antiviral and antibacterial chewing gums reduce the levels of three microbes linked to worse outcomes in oral cancers, paving the way for more effective and affordable therapies.
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NewsEngineered dual-bacterial sensors turn chemical signals into electricity
Most bacterial information transmission is done via electricity. While electricity-emitting bacteria exist, manipulating them into useful sensors has been quite challenging. Researchers recently developed a flexible bioelectrical sensor system called electroactive co-culture sensing system.
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NewsDon’t build the engine, grow it: biohybrid miniature robots using living organisms
By fusing living organisms like bacteria, algae, and insects with synthetic payloads, researchers are creating living biohybrid miniature robots that self-fuel, self-repair, and navigate environments that would paralyze a rigid silicon chip.
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NewsResearchers synthesize photosynthetic molecule found in bacteria
Researchers have successfully synthesized bacteriochlorophyll a, a photosynthetic pigment found in bacteria which absorbs infrared light. The work represents the first chemical synthesis of this molecule and could give scientists deeper insights into photosynthetic function and photosynthetic energy.
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NewsA built-in ‘hairpin’ prevents rogue CRISPR RNAs
A new study reveals that many CRISPR-Cas13 systems utilize an RNA to prevent the formation of extraneous CRISPR RNA. With the first repeat, this protective RNA forms a stable structure resembling a hairpin. It points to a remarkable case of convergent evolution.
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NewsNew bite-sized CRISPR molecule may open doors for therapeutic genome editing
The safest, most accurate gene-editing tools don’t fit inside viral delivery mechanisms that could target them to specific cell types or tissues inside the human body. Researchers have developed a smaller pair of “molecular scissors” for gene editing that could make site-specific delivery within the body possible.
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NewsEngineered bacteria unlock seaweed potential: dual enzyme system enables complete alginate depolymerization
A research team has heterologously expressed alyB and alyD genes from the marine bacterium Vibrio algivorus in C. glutamicum, an industrial workhorse traditionally used for amino acid production.
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NewsBiosensor detects early fungal outbreaks, advances plant biotechnology
A new biosensor detects the emerging presence of fungus on plants at the molecular level, paving the way for next-generation crop protection and the development of stress-tolerant plants.
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NewsEngineered bacteria deliver cancer drug directly inside tumors in mice
New research suggests that Escherichia coli Nissle 1917 (EcN) may be engineered with anticancer agents to treat cancerous tumors in mice. Researchers used EcN as a base for synthesizing Romidepsin (FK228), an FDA-approved drug with anti-tumor agents.
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NewsEngineered yeast gives the US a green edge in the critical minerals market
A new, U.S.-based, environmentally friendly method for mining rare-earth elements used in consumer electronics, clean energy, defense and biomedical imaging uses oxalic acid made by sugar-eating engineered yeast, extracting almost all the rare-earth elements from low-grade ore.
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NewsNew gel-based system allows bacteria to act as bioelectrical sensors
Researchers have developed a safe bioelectronic sensor that allows for effective electronic communication even in liquid environments. The system uses the naturally occurring polymer chitosan, acting as a kind of shell to keep the bacteria from escaping.
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NewsFreshwater alga captures far-red light for photosynthesis by rearranging ordinary chlorophyll
To survive in areas where it is difficult to photosynthesize, some organisms adopt unique strategies. Researchers have found that a freshwater alga captures far-red light as an additional energy source by arranging ordinary chlorophyll in an extraordinary way.
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NewsScientists design metal-enhanced biochar to boost clean hydrogen production from agricultural waste
A new study reports that specially engineered biochar made from agricultural waste could significantly increase biohydrogen production by improving the way microbes transfer electrons during fermentation.
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News‘Bugs delivering drugs’ – new approach to colorectal cancer treatment using common food-borne bacteria
Researchers have published a novel approach to fight colorectal cancer, using modified bacteria as a courier to deliver potent cancer-killing proteins into tumor cells.
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NewsResearchers make probiotic safer for immunocompromised patients
Researchers have modified a probiotic yeast to make it safer for use by immunocompromised people, older adults and infants. Testing in an animal model found the modified yeast is less likely to cause infection than unmodified strains of the same organism.
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NewsTrust your gut to heal your brain
Researchers have found that short-term antibiotic treatment significantly reduced neuroinflammation and neurodegeneration following traumatic brain injury (TBI) by altering the gut microbiome in animal models.