All Bioengineering articles
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New, modified CRISPR protein can fit inside virus used for gene therapy
Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells. Hongjian Wang and colleagues at Wuhan University, China, present these findings May 23rd in the ...
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Living bioelectronic device monitors and manages psoriasis in mice
Coupling skin bacteria-laden hydrogel and electronics, researchers have introduced a bioelectronics system that can deliver management and adaptive treatment of skin inflammation. They test this approach in a mouse model of psoriasis.
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Scientists harness plant viruses to deliver genome editing reagents in diverse plant species
The use of viral vectors to deliver genome editing components offers potential solutions to many current technical bottlenecks involved in genome editing in plants.
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Bioengineered enzyme creates natural vanillin from plants in one step
Researchers have developed an enzyme which can convert ferulic acid from plant waste into vanillin – the classic vanilla flavored compound.
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An adjuvant made in yeast could lower vaccine cost and boost availability
Scientists have wielded the power of synthetic biology to produce the active ingredient of soap bark, a molecule called QS-21, in yeast - a more environmentally friendly way to produce a key ingredient of vaccines.
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Innovative antiviral defense with new CRISPR tool
Scientists outline how they have overcome a significant obstacle that has hampered the effectiveness of Cas13d: its restriction to the nucleus of mammalian cells.
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From lab to grid: how living batteries could transform the energy landscape
As researchers find innovative ways to make these power sources more lightweight or longer-lasting, they must also ensure that their inventions are as sustainable as possible.
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Plastic-free vegan leather that dyes itself grown from bacteria
Researchers at Imperial College London have genetically engineered bacteria to grow animal- and plastic-free leather that dyes itself. In recent years, scientists and companies have started using microbes to grow sustainable textiles or to make dyes for industry – but this is the first time bacteria have been engineered to ...
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Study identifies protein responsible for gas vesicle clustering in bacteria
Scientists have presented the first identification of a protein that can regulate the honeycomb patterning of gas vesicles packed within microbes.
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New bioengineered protein design shows promise in fighting COVID-19
Researchers have designed a novel protein capable of binding to the spike proteins found on the surface of the coronavirus, allowing them identify and recognize the virus for diagnostic purposes, and to hinder its ability to infect human cells.
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Researchers open new leads in anti-HIV drug development, using a compound found in nature
Researchers have successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
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3G microbial cell factories: achieving sustainable goals with engineered microorganisms
Scientists review the progress made in the development of artificial biological systems for 3G refineries over the last decade.
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Bacteria engineered to biosynthesize intricate protein complexes
Researchers have developed an innovative bioengineering approach using genetically modified bacteria that can incorporate protein cages around protein crystals, producing highly customized protein complexes.
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Fast-track strain engineering for speedy biomanufacturing
The time and money required to engineer microbes to produce vital medicines and chemicals can be dramatically reduced with a new model-based method.
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Scientists uncover mechanism underlying heat shock response in E coli
A study focusing on IbpA, one of the small heat shock proteins, has shed new light on the involvement of this previously unrecognized factor in the heat shock response of E. coli.
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Gene-editing technology eliminates EV-A71 RNA viruses
Scientists have developed a CRISPR-Cas13 therapeutic against EV-A71, the RNA virus that causes hand, foot, and mouth disease.
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European-funded €2.3m project will revolutionize bioprinting of living materials
The PRISM-LT project has received a €2.3 million grant for a five-year program that aims to create an adaptable platform for 3D bioprinting of living tissue with dynamic functionalities and predictable shapes.
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Algae transformed into unique functional perovskites with tunable properties
Scientists have transformed mineral shells of algae into functional perovskites with unique crystal structures and controllable electro-optical properties.
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Semi-living cyborg cells could be tools for health and environment
Biomedical engineers at the University of California have created semi-living ’cyborg cells’ retaining the capabilities of living cells, but unable to replicate.
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Electricity-fed purple phototrophic bacteria convert carbon dioxide into high protein biomass
For the first time, researchers from University of Alcalá have grown a microbial consortium dominated by purple phototrophic bacteria (PPB) which are fed with electricity to convert CO2 into high protein biomass.