All Bioengineering articles
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NewsEngineered bacteria deliver cancer drug directly inside tumors in mice
New research suggests that Escherichia coli Nissle 1917 (EcN) may be engineered with anticancer agents to treat cancerous tumors in mice. Researchers used EcN as a base for synthesizing Romidepsin (FK228), an FDA-approved drug with anti-tumor agents.
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NewsEngineered yeast gives the US a green edge in the critical minerals market
A new, U.S.-based, environmentally friendly method for mining rare-earth elements used in consumer electronics, clean energy, defense and biomedical imaging uses oxalic acid made by sugar-eating engineered yeast, extracting almost all the rare-earth elements from low-grade ore.
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NewsNew gel-based system allows bacteria to act as bioelectrical sensors
Researchers have developed a safe bioelectronic sensor that allows for effective electronic communication even in liquid environments. The system uses the naturally occurring polymer chitosan, acting as a kind of shell to keep the bacteria from escaping.
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NewsFreshwater alga captures far-red light for photosynthesis by rearranging ordinary chlorophyll
To survive in areas where it is difficult to photosynthesize, some organisms adopt unique strategies. Researchers have found that a freshwater alga captures far-red light as an additional energy source by arranging ordinary chlorophyll in an extraordinary way.
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NewsScientists design metal-enhanced biochar to boost clean hydrogen production from agricultural waste
A new study reports that specially engineered biochar made from agricultural waste could significantly increase biohydrogen production by improving the way microbes transfer electrons during fermentation.
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News‘Bugs delivering drugs’ – new approach to colorectal cancer treatment using common food-borne bacteria
Researchers have published a novel approach to fight colorectal cancer, using modified bacteria as a courier to deliver potent cancer-killing proteins into tumor cells.
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NewsResearchers make probiotic safer for immunocompromised patients
Researchers have modified a probiotic yeast to make it safer for use by immunocompromised people, older adults and infants. Testing in an animal model found the modified yeast is less likely to cause infection than unmodified strains of the same organism.
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NewsTrust your gut to heal your brain
Researchers have found that short-term antibiotic treatment significantly reduced neuroinflammation and neurodegeneration following traumatic brain injury (TBI) by altering the gut microbiome in animal models.
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NewsA single gene, a dramatic change: CRISPR unlocks white strawberries
Researchers used CRISPR/Cas9 to selectively edit a single dominant gene copy controlling fruit color in the commercial octoploid strawberry cultivar ‘Florida Brilliance’. By targeting the MYB10-1B gene, they successfully converted red strawberries into stable white-fruited plants.
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NewsRhododendron-derived drugs now made by bacteria
Bioengineered E. coli bacteria can now produce a group of compounds with anticancer, anti-HIV, antidiabetic and anti-inflammatory activities. The compounds, orsellinic acid-derived meroterpenoids, are produced by Rhododendron species.
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NewsTechnology transfer for Corallopyronin A successfully completed with Phyton Biotech
Phyton Biotech has successfully transferred the manufacturing process for the microbial production of Corallopyronin A (CorA). CorA is a novel anti-infective agent with the potential to address neglected tropical diseases.
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NewsTaxiing through the gut: Formic acid in the microbiome
Scientists have found that the gut bacterium Blautia luti produces formic acid (formate) instead of carbon dioxide (CO₂) and hydrogen, with hydrogen bound to CO₂. In this case, formic acid is the electron taxi, allowing the energetically costly production of hydrogen to be bypassed.
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NewsGreen chemistry: Friendly bacteria can unlock hidden metabolic pathways in plant cell cultures
Co-culturing plant cells with harmless bacteria can expand the diversity of obtainable plant-derived compounds for pharmaceuticals, cosmetics, and agrochemicals, a new study shows.
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NewsGenetic system makes worker cells more resilient producers of nanostructures
Researchers report the development of a new genetic regulatory system to improve cell viability during the production of gas vesicles.
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NewsNaval Research Lab Space Station study reveals key challenges and opportunities for microbial biomanufacturing in space
Scientists have completed a spaceflight biology investigation aboard the International Space Station (ISS) that reveals how microgravity fundamentally alters microbial metabolism, limiting the efficiency of biological manufacturing processes critical to future long-duration space missions.
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NewsScientists synthesize medicarpin in baker’s yeast
Scientists have developed a way to synthesize medicarpin in yeast. Like palitaxel in the 1990s, this tumor-attacking sustance has only limited natural quantitites and is considered difficult to synthesize.
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NewsScientists engineer quantum-enabled proteins, opening a new frontier in biotechnology
A new study reports the creation of a new class of biomolecules, magneto-sensitive fluorescent proteins, that can interact with magnetic fields and radio waves. This is enabled by quantum mechanical interactions within the protein, and occur when it is exposed to light of an appropriate wavelength.
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NewsGame-changer for rare sugars: alkaline media unlocks high yield of rare sugars from bacteria
Bacterial EPSs (exopolysaccharides) are emerging as a sustainable source of rare sugars, offering advantages including higher yields and lower environmental impact.
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NewsScientists reprogramme E. coli to transform sugars into eco-friendly surfactant
A new study demonstrates a sustainable microbial strategy for producing lauryl glucoside by engineering a non-natural biosynthetic pathway in Escherichia coli, revealing precursor availability as a key bottleneck and moving towards greener biomanufacturing.
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NewsGolden Gate method enables rapid, fully-synthetic engineering of therapeutically relevant bacteriophages
Researchers have described the first fully synthetic bacteriophage engineering system for Pseudomonas aeruginosa. In this method, researchers engineer bacteriophages synthetically using sequence data rather than bacteriophage isolates.