All Bioengineering articles – Page 2
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NewsYeast produces human DNase1 for the first time
The protein DNase1 is used to treat cystic fibrosis but it takes considerable effort and cost to produce it in immortalized hamster cells. Researchers have now produced it in yeast cells for the first time.
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NewsHigh-density screening technique reveals key genes for biotechnology improvements
Scientists used a gene-silencing tool and molecular guides to probe how photosynthetic bacteria adapt to light and temperature changes, finding even partial suppression of certain genes yielded big benefits in modifying the stress response of wild microbes.
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NewsResearch advances on ‘displacing’ antibiotic resistance gene from bacteria
Scientists have identified essential genetic code for a method called plasmid curing, which aims to ‘displace’ antibiotic resistance genes from bacteria.
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NewsDesigner microbe shows promise for reducing mercury absorption from seafood
Scientists who inserted DNA-encoding methylmercury detoxification enzymes into the genome of an abundant human gut bacterium found it detoxified methylmercury in the gut of mice and dramatically reduced the amount that reached other tissues.
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NewsBacteria deployed as living test tubes to study human gene mutations
Bioengineers have developed a new simple approach to rapidly check on human gene changes and also screen chemicals as potential drugs by turning everyday bacteria into living test tubes.
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NewsEngineered bacteria emit signals that can be spotted from a distance
Engineers have found a way to read out bacterial signals from as far as 90 meters away. This work could lead to the development of bacterial sensors for agricultural and other applications, which could be monitored by drones or satellites.
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NewsMicroalgae and bacteria team up to convert CO2 into useful products
Most methods of genetically modifying the bacterium Escherichia coli and other microbes to convert carbon dioxide into useful biological products require additional carbon sources. A new study overcomes this limitation by combining the photosynthetic finesse of a single-celled algae with the production capabilities of the bacteria E. coli.
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NewsScientists devise comprehensive resource on microbial cell factories for sustainable chemical production
Scientists evaluated the production capabilities of various industrial microbial cell factories using in silico simulations and, based on these findings, identified the most suitable microbial strains for producing specific chemicals as well as optimal metabolic engineering strategies.
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NewsScientists unlock frogs’ antibacterial secrets to combat superbugs
Researchers exploited natural peptides derived from frogs and improved their structural designs as antibiotic candidates, which are effective against complex mock bacterial communities of drug-resistant pathogens in preclinical tests, sparing beneficial microbiota and human cells.
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NewsGreen recipe: Engineered yeast boosts D-lactic acid production
An optimal combination of genetic “recipe” in a yeast strain achieves high yields of D-lactic acid production from methanol, advancing eco-friendly and sustainable biomanufacturing.
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NewsRice research team creates universal RNA barcoding system for tracking gene transfer in bacteria
An interdisciplinary group of researchers at Rice University has developed an innovative RNA “barcoding” method to track gene transfer in microbial communities, providing new insights into how genes move across species.
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NewsMagnetic microalgae on a mission to become robots
A team of researchers has developed a green algae-based biohybrid micro swimmer covered with magnetic material, whose swimming ability is largely unaffected by the coating.
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NewsNew CRISPR-based diagnostic test detects multidrug-resistant pathogens in blood without amplification
A highly sensitive amplification-free CRISPR-based diagnostic test is developed to rapidly detect pathogens, including multidrug-resistant bacteria, at low concentrations in blood samples.
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NewsCeSPIACE: A broad-spectrum peptide inhibitor against variable SARS-CoV-2 spikes
CeSPIACE, a small remodified peptide, is able to block the binding of ACE2 receptor and the spike protein on SARS-CoV-2 and its variants. Hence, the cheap and simple peptide could treat COVID-19 infection and prevent reinfection after exposure of the virus.
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NewsNew CRISPRs expand upon the original’s abilities
By scouring through a massive bacterial metagenomic databases, researchers have discovered new CRISPR-Cas systems as efficient as the conventional one. One of the candidate system has found with the technological potential to expand its impact in research, biotechnology and medicine.
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NewsPromising new research shows potential to cure recurrent urinary tract infectionsed
Researchers examine the effectiveness of nanogel as a drug delivery system to direct antibiotics into targeted infected cells to improve UTI treatment.
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NewsNew antibodies show potential to defeat all SARS-CoV-2 variants
Researchers discovered that a paired combination of antibodies binding to the two domains of the SARS-CoV-2 viral particle showed promising results in elimination of all virus variants caused in the COVID-19 pandemic.
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NewsResearchers reveal key mechanism behind bacterial cancer therapy
A research team has elucidated the mechanism behind bacterial cancer therapy using a genetically engineered bacterial strain.
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NewsDesigning self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.
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NewsBiosensing platform simultaneously detects vitamin C and SARS-CoV-2
A portable and sensitive biosensing device has been developed by engineering researchers to detect both SAR-CoV-2 and vitamin C simultaneously, to monitor and boost health for the general public.