All Bioengineering articles
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NewsRevolutionizing bioplastics: a microbial platform for fully bio-based long-chain polyesters
Researchers have developed a scalable, end-to-end microbial process transforming plant oils into sustainable polyesters comparable to petroleum-based plastics.
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NewsExpanding the genetic toolkit: nitrogen-response promoters developed for Bacillus licheniformis
Promoters are crucial expression elements in synthetic biology, and Bacillus licheniformis serves as an excellent chassis cell for industrial production, but is restricted by a lack of nitrogen source-responsive promoters.
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NewsScientists develop rapid and scalable platform for in planta directed evolution
Researchers have developed a new system that enables rapid and scalable directed evolution of diverse genes directly in plant cells. To address the challenge of slow cell division rate in plants, the researchers harnessed geminiviruses.
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NewsGene editing, traditional crossbreeding produce disease-resistant cacao plants
Researchers reported that they edited the gene TcNPR3 in cacao plants, ultimately resulting in disease-resistant cacao plants that had 42% smaller disease lesions when infected with phytophthora, compared to non-edited plants.
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NewsBalance is key: Strategies to boost protein production from engineered cells
New research demonstrates how to engineer ‘cell factories’ that last longer and produce more chemicals, without needing antibiotics or complex engineering methods, paving the way for sustainable biotech that lasts.
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NewsEngineered gut bacteria improves survival outcomes in colorectal cancer tumors
A genetically modified Salmonella typhimurium strain can colonise tumours and release a therapeutic protein, LIGHT, to induce the formation of mature tertiary lymphoid structures (mTLSs) in laboratory models.
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NewsAI uncovers hidden rules of some of nature’s toughest protein bonds
Scientists have shown how artificial intelligence can reveal the hidden rules of one of biology’s strangest phenomena: catch-bonds – molecular interactions that get stronger when pulled. Their findings shed light on how bacteria cling to surfaces, how tissues resist tearing, and how new biomaterials might be designed to harness force.
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NewsCoral-inspired pill offers a new window into the hidden world of the gut
Marine corals have evolved intricate, porous structures that shelter diverse microbial communities. Researchers have borrowed this biological blueprint to create an ingestible pill that can sample bacteria from one of the most inaccessible regions of the human body: the small intestine.
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NewsGame-changing biotech for engineering pathogen-resistant crops
Researchers have identified an ancient protein that has the potential to help defend plants against tens of thousands of different bacteria and other pathogens. Dubbed “SCORE”, this receptor detects cold-shock protein—variations of which are found in more than 85% of known bacteria, as well as fungi and insects.
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NewsBiodegradable PET alternative bioproduced at unprecedented levels
The PET-alternative PDCA is biodegradable and has superior physical properties. A team of bioengineers has engineered E. coli bacteria to produce the compound from glucose at unprecedented levels and without byproducts — and opened up a realm of possibilities for the future of bioengineering.
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NewsPretreatment methods deploying microbes bring second-gen biofuels from oilcane closer to commercialization
In collaboration with other Bioenergy Research Centers (BRCs), researchers at the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) are developing industrially feasible techniques for second-generation biofuel production from oilcane, an oil-rich variety of sugarcane, to help meet our growing societal demand for fuels. Source: April Wendling/CABBI CABBI ...
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NewsResearch team on quest to engineer computing systems from living cells
A research team has received a $1.99 million grant to lead research on engineered bacterial consortia that could form the basis of biological computing systems. They aim to integrate microbial sensing and communication with electronic networks, paving the way for computing systems constructed from living cells instead of traditional silicon-based hardware.
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NewsBacteria rewire digestive systems to turn plant waste into power
A new study shows that Pseudomonas putida, a common soil bacterium, completely reorganizes its metabolism to thrive on complex carbons from lignin. By slowing down some metabolic pathways while accelerating others, the bacterium manages to extract energy from lignin without exhausting itself.
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News‘Essentiality’ scan reveals microbe’s ‘must-have’ list
Researchers have spent years taking apart one of the world’s simplest microbes, Mycoplasma pneumoniae, piece by piece, and created a detailed list of what molecular parts the living cell can and cannot do without.
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News‘Controlled evolution’ dramatically boosts pDNA production for biomedical manufacturing
Researchers have controlled the evolution of E. coli bacteria in the lab in order to dramatically increase the amount of plasmid DNA (pDNA) these modified bacteria produce. pDNA is an essential – and expensive – ingredient in many gene therapies.
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NewsCommon food bacterium could help make vitamins cheaper and greener
A new study reveals how Lactococcus lactis, a common food bacterium, regulates the production of a key precursor in vitamin K₂ (menaquinone) biosynthesis. The bacteria produce enough of this precursor to support their growth while preventing toxic buildup.
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NewsReady for market: Yeast process boosts clean, cost-efficient chemical production of succinic acid
A re-engineered yeast strain that efficiently produces succinic acid has been developed, which allows this valuable chemical to be produced at a lower cost.
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News‘Major leap in bioelectronic sensing’: researchers turn bacteria into tiny pollution detectors
Researchers have engineered E. coli to act as living multiplexed sensors, allowing these genetically modified cells to detect and respond to multiple environmental toxins simultaneously by converting their biological responses into readable electrical signals.
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NewsMetabolic engineering boosts yeast antioxidant power for drug production
A recent study engineered the yeast Candida glabrata to boost its resistance to oxidative stress, a common challenge in industrial bioproduction. The team enhanced the yeast’s ability to produce malate, a key molecule linked to antioxidant activity.
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NewsControlled human gut colonization by an engineered microbial therapeutic
Engineered gut bacteria designed to treat kidney stones successfully colonized the gut microbiome and reduced oxalate levels in animal models and early clinical trials in humans, researchers report.