All Bioengineering articles – Page 4
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NewsBacteria ‘pills’ could detect gut diseases — without the endoscope
Researchers report that they’ve developed a sensor made of tiny microspheres packed with blood-sensing bacteria that detect markers of gastrointestinal disease. Taken orally, the miniature “pills” also contain magnetic particles that make them easy to collect from stool. Excreted from mouse models with colitis, the bacterial sensor detected gastrointestinal bleeding within minutes.
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NewsNext-generation microbiome medicine may revolutionize the treatment of Parkinson’s and similar disorders
Scientists have engineered the probiotic bacterium Escherichia coli Nissle 1917 as a drug-delivery system that continuously produces and delivers the gold-standard Parkinson’s drug Levodopa, which is converted to dopamine in the brain. E. coli Nissle strain was chosen for its century-long record of safely treating gastrointestinal disorders in humans.
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NewsNew blueprint for nature’s carbon-capturing nanomachines revealed
Researchers have uncovered how bacterial organelles assemble, opening new routes for bioengineering and climate innovation. The team has unveiled the most detailed picture yet of how bacteria construct microscopic compartments known as carboxysomes – natural nanomachines that play a vital role in capturing and converting carbon dioxide (CO₂).
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NewsBacterial spores offer promise of sustainable smart materials
By embedding Bacillus spores within engineered living materials, researchers have created living materials that not only endure harsh environments but can also be programmed to perform specific tasks. These materials may be a sustainable replacement for fossil-based materials.
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NewsRODIN project will invest 10 M€ to explore cells as the architects of future biomaterials
RODIN - Cell-mediated Sculptable Living Platforms - is set to revolutionize the field of biomaterials and tissue engineering by shifting the focus from designing materials for cells to empowering cells to design their own environments.
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NewsEngineered membraneless organelles boost bioproduction in Corynebacterium glutamicum
Scientists have successfully engineered liquid-liquid phase separation (LLPS)-driven membraneless organelles (MLOs) within the food-grade industrial strain Corynebacterium glutamicum.
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NewsHow algae help corals bounce back after bleaching
A $1.1 million project will uncover how reefs regain life-giving algae after suffering from heat stress. The three-year project will use advanced imaging and living experimental systems to learn what’s happening on a cellular level when algae return to bleached reefs.
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NewsBiomaterial vaccines to make implanted orthopedic devices safer
Biomaterial vaccines using pathogen-specific antigens could significantly lower patients’ risk of infection from implanted medical devices.
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NewsCofactor engineering with phosphite dehydrogenase enables flexible regulation of lactate-based copolymer biosynthesis in E. coli
A new breakthrough enables higher yields of poly(3-hydroxybutyrate-co-lactate) [P(3HB-co-LA)] without disrupting bacterial growth, paving the way for more sustainable bioplastic manufacturing.
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NewsRevolutionizing bioplastics: a microbial platform for fully bio-based long-chain polyesters
Researchers have developed a scalable, end-to-end microbial process transforming plant oils into sustainable polyesters comparable to petroleum-based plastics.
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NewsExpanding the genetic toolkit: nitrogen-response promoters developed for Bacillus licheniformis
Promoters are crucial expression elements in synthetic biology, and Bacillus licheniformis serves as an excellent chassis cell for industrial production, but is restricted by a lack of nitrogen source-responsive promoters.
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NewsScientists develop rapid and scalable platform for in planta directed evolution
Researchers have developed a new system that enables rapid and scalable directed evolution of diverse genes directly in plant cells. To address the challenge of slow cell division rate in plants, the researchers harnessed geminiviruses.
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NewsGene editing, traditional crossbreeding produce disease-resistant cacao plants
Researchers reported that they edited the gene TcNPR3 in cacao plants, ultimately resulting in disease-resistant cacao plants that had 42% smaller disease lesions when infected with phytophthora, compared to non-edited plants.
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NewsBalance is key: Strategies to boost protein production from engineered cells
New research demonstrates how to engineer ‘cell factories’ that last longer and produce more chemicals, without needing antibiotics or complex engineering methods, paving the way for sustainable biotech that lasts.
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NewsEngineered gut bacteria improves survival outcomes in colorectal cancer tumors
A genetically modified Salmonella typhimurium strain can colonise tumours and release a therapeutic protein, LIGHT, to induce the formation of mature tertiary lymphoid structures (mTLSs) in laboratory models.
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NewsAI uncovers hidden rules of some of nature’s toughest protein bonds
Scientists have shown how artificial intelligence can reveal the hidden rules of one of biology’s strangest phenomena: catch-bonds – molecular interactions that get stronger when pulled. Their findings shed light on how bacteria cling to surfaces, how tissues resist tearing, and how new biomaterials might be designed to harness force.
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NewsCoral-inspired pill offers a new window into the hidden world of the gut
Marine corals have evolved intricate, porous structures that shelter diverse microbial communities. Researchers have borrowed this biological blueprint to create an ingestible pill that can sample bacteria from one of the most inaccessible regions of the human body: the small intestine.
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NewsGame-changing biotech for engineering pathogen-resistant crops
Researchers have identified an ancient protein that has the potential to help defend plants against tens of thousands of different bacteria and other pathogens. Dubbed “SCORE”, this receptor detects cold-shock protein—variations of which are found in more than 85% of known bacteria, as well as fungi and insects.
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NewsBiodegradable PET alternative bioproduced at unprecedented levels
The PET-alternative PDCA is biodegradable and has superior physical properties. A team of bioengineers has engineered E. coli bacteria to produce the compound from glucose at unprecedented levels and without byproducts — and opened up a realm of possibilities for the future of bioengineering.
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NewsPretreatment methods deploying microbes bring second-gen biofuels from oilcane closer to commercialization
In collaboration with other Bioenergy Research Centers (BRCs), researchers at the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) are developing industrially feasible techniques for second-generation biofuel production from oilcane, an oil-rich variety of sugarcane, to help meet our growing societal demand for fuels. Source: April Wendling/CABBI CABBI ...