All Candida albicans articles
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Maleimide derivative shows promise for treating clinical candidiasis
A new study demonstrates the efficacy of a novel maleimide analogue as a novel antifungal compound, highlighting its potential as a promising option for the treatment of clinical candidiasis.
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Candida albicans toxin plays a special role in the colonization of the digestive tract
Comparative studies on mice with a complete microbiome and a microbiome reduced by antibiotics now show that the previous assumption that the yeast form of Candida albicans is better suited for colonization needs to be revised.
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Insights into release of fungal toxin promise progress in treating infections
The toxin Candidalysin of the yeast Candida albicans is incorporated into an unusual protein structure during an infection, and researchers have now succeeded in deciphering the function of this unusual arrangement.
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Newly identified yeast could prevent fungal infections by outcompeting rivals, study suggests
Researchers have identified a yeast that could be used to prevent invasive candidiasis, a major cause of death in hospitalized and immunocompromised patients.
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Current standards for testing wound dressings don’t work for biofilms, study finds
Current standards for testing wound dressings do not work for biofilms, particularly in the case of polymicrobial biofilms, a new study has found. Testing of wound dressings is predominantly carried out on single species of microbes in isolation, even though the wound sterile environment is not sterile and is often ...
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Zinc shows promise as surprising emerging treatment for vaginal yeast infections
New research could one day pave the way for the treatment of vaginal yeast infections, by shedding new light on how microbes in the body absorb zinc.
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Visualizing fungal infections deep in living tissue reveals proline metabolism link to virulence
The first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host reveals that Candida albicans requires the ability to metabolize proline to mount virulent infections.
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Drugs targeting iron regulation could be the answer to antifungal resistance
Drugs targeting iron uptake mechanisms could prove vital in the fight against human fungal pathogens, a new review suggests.
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Gut fungi trigger long-lasting severe COVID-19 immune response
Researchers have found that the growth of fungi in the intestinal tract, particularly strains of Candida albicans yeast, trigger an upsurge in immune cells whose actions can exacerbate lung damage.
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Fungal infection in the brain produces changes like those seen in Alzheimer’s disease
Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and generates amyloid beta (Ab)-like peptides.
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Fungal toxin triggers NET traps formed by white blood cells
A new study sheds light on how neutrophils respond to C. albicans hyphae, which release a peptide toxin called candidalysin, exclusively secreted when C. albicans grows as hyphae and hence during invasive growth.
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Gut hormone doubles as immune regulator for the fungal microbiome
Research shows that a gut hormone called peptide YY also plays a vital role in maintaining the health of the gut microbiome by preventing helpful fungi from turning into more dangerous, disease-causing forms.
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Fungal infections are an unintended consequence of advanced immunotherapy
Researchers have shown how clinical use of some monoclonal antibodies may cause life-threatening systemic fungal infections.
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Nanorobots seek and destroy fungal infections in the mouth
Researchers have developed a new way to rapidly and precisely eradicate fungal infections in the mouth by using nanorobots guided by magnets.
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Living yeast-based dual biosensor detects peptides
The state-of-the-art biosensor with a visible readout could have potential applications in virus detection, diagnostics, and other areas.
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Altered gut microbes may be linked to childhood ADHD susceptibility
New research suggests that the microbial composition of the gut may affect a child’s susceptibility to attention-deficit/hyperactivity disorder (ADHD).
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Deadly Keanu-inspired bacterial compound delivers excellent anti-fungal protection to plants
Researchers have proved that an antimicrobial natural product produced by Pseudomonas - and named after Keanu Reeves - is effective against both plant fungal diseases and human-pathogenic fungi.
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Oral bacteria team up with fungi to form cavity-forming superorganisms
Oral bacteria can join forces with fungi to form cavity-causing “superorganisms” that sprout limblike structures, according to a study in the Proceedings of the National Academy of Sciences (PNAS).