All HIV articles
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Supercharged HIV vaccine could offer strong protection with just one dose
Researchers have shown that they can generate a strong immune response to HIV with just one vaccine dose, by adding two powerful adjuvants — materials that help stimulate the immune system.
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Scientists discover key protein that enables ‘shock & kill’ strategy for HIV latent virus clearance
Researchers have identified a specific gene transcription factor, BRD9, as a potential key to unlocking the mechanisms behind HIV-1 latency.
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Scientists decipher HIV-1 transcription initiation and elongation from single-molecule imaging data
Scientists have developed a dual-driven framework based on single-molecule imaging data and stochastic dynamic modeling to infer HIV-1 transcription dynamics.
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Antibiotics taken during pregnancy may reduce preterm births
A study of almost 1000 pregnant women in Zimbabwe found that a daily dose of a commonly used, safe and inexpensive antibiotic may have led to fewer babies being born early.
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Multiple testing for infectious diseases among migrants key to cutting onward transmission
Routine testing for multiple infectious diseases among migrants will benefit healthcare systems by identifying key infections earlier, a new study finds.
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HIV discovery could open door to long-sought cure
Scientists have uncovered a key reason why HIV remains so difficult to cure: Their research shows that small changes in the virus affect how quickly or slowly it replicates, and how easily or stubbornly it can reawaken from hiding.
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New diagnostic tool uses bioluminescence to detect viruses
Researchers are shining a powerful new light into the viral darkness with the development of Luminescence CAscade-based Sensor (LUCAS), a rapid, portable, highly-sensitive diagnostic tool for processing complex biological samples.
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Portable HIV monitoring device shows promise for remote settings
A newly developed microfluidic biosensor promises to reshape how CD4+ T cells — key indicators of immune function in Human Immunodeficiency Virus (HIV) patients — are detected.
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The Global Fund to fight AIDS, Tuberculosis and Malaria ‘should step up efforts’
The international community must protect global responses to HIV, tuberculosis (TB), and malaria to serve humanity’s collective interests, according to a new opinion article.
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Two HIV vaccine trials show proof of concept for pathway to broadly neutralizing antibodies
A new study combining data from two separate phase 1 clinical trials shows that a targeted vaccine strategy can successfully activate early immune responses relevant to HIV, and, in one trial, further advance them.
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Proof of concept for HIV vaccination that deploys germline-targeting
For a preventative HIV-vaccine to work it should induce broadly neutralising antibodies against all the diverse strains of the virus. The first in-human assessment of germline-targeting strategy with a trimer displays positive results.
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‘Loop’hole: HIV-1 hijacks human immune cells using circular RNAs
In a groundbreaking discovery, researchers have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body’s natural defenses and use it to support its survival and replication.
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Scientists win award for bringing breakthrough HIV treatment lenacapavir into play
Three people have been awarded the AAAS Mani L. Bhaumik Breakthrough of the Year Award for their work on the first HIV drug to offer long-lasting protection from infection — eliminating the need for people to take a daily pill.
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New CDC nPEP Guidelines should become ‘part of general medical practice’
Health experts say the updated CDC HIV Non-Occupational Post Exposure Prophylaxis (nPEP) Guidelines should be part of general medical practice, as incorporating them will reduce new HIV infections and improve public health.
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Antibodies that recognize lipids: A new path for HIV vaccines and autoimmune disease treatments
Scientists have used computer modeling to illustrate how a specific class of antibodies actually use lipids to recognize the HIV virus. The work highlights antibody features that could help people design better vaccines for HIV and autoimmune diseases.
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New treatment for cryptococcal meningitis enters Phase II trial
Cryptococcal meningitis, the second-leading cause of HIV-related deaths, is expected to rise as access to care weakens and advanced HIV disease (previously called AIDS) increases.
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Eliminating worm infections as a key strategy for HIV/AIDS prevention
Scientists who found that infection with the worm Wuchereria bancrofti increases the risk of contracting HIV have now confirmed, as part of a national program in Tanzania, that containment of this worm infection leads to a reduction in new HIV infections.
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Novel point-of-care technology delivers accurate HIV results in minutes
Scientists have developed new technology that could lead to the creation of a rapid point-of-care test for HIV infection competitive with traditional lab-based HIV testing in a fraction of the time and without the need for a stressful wait.
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Molecular stool test could improve detection of tuberculosis in adults with HIV
A prospective multicentre study highlights the potential of the Xpert MTB/Ultra stool test for diagnosing tuberculosis in people living with HIV.
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FAU secures $1.3 million NIH grant for breakthrough in HIV self-test technology
To address the urgent need for a reliable, rapid and affordable self-test for early HIV detection, researchers have been awarded phase-II of a five-year, $1.3 million grant which will support the development of an innovative disposable microchip technology designed for HIV-1 self-testing during the first two weeks post-infection.