All HIV articles
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CRISPR-based therapeutics hold potential to combat AMR and cure chronic viral infections, says GlobalData
CRISPR-based therapeutics show potential to combat antimicrobial resistance (AMR) and deliver functional cures for chronic viral infections, says GlobalData, a leading data and analytics company.
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Early challenges to the immune system disrupt oral health
Researchers identified changes over time in the oral microbiome of children living with HIV, offering insights into how early immune challenges shape not only oral health but also systemic health.
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Scientists discover how leukemia virus stays hidden in the body
A research team has discovered how the human T-cell leukemia virus type 1 (HTLV-1) silently persists in the body. Their findings identify a previously unknown genetic “silencer” element that keeps the virus in a dormant, undetectable state.
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Gene therapy may block HIV transmission during breastfeeding, study shows
Delivering broadly neutralizing antibodies against HIV-1 to newborns via gene therapy provided them with multi-year protection from HIV/AIDS infection, according to an animal study.
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‘One and done’: A single shot at birth may shield children from HIV for years, study finds
A new study shows that delivering a single injection of gene therapy at birth may offer years-long protection against HIV, tapping into a critical window in early life that could reshape the fight against pediatric infections in high-risk regions.
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Study suggests some maternal HIV infections may be missed during pregnancy
Newborns exposed to HIV during pregnancy or birth should receive antiretroviral medication immediately after delivery - but a study finds more than half of infants diagnosed with HIV in their first year of life had not received this essential postnatal treatment.
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Tiny chip speeds up antibody mapping for faster vaccine design
By analyzing just a drop of blood, this microchip gives researchers quicker-than-ever insight into how a person’s antibodies are interacting with a virus or other pathogen.
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Supercharged HIV vaccine could offer strong protection with just one dose
Researchers have shown that they can generate a strong immune response to HIV with just one vaccine dose, by adding two powerful adjuvants — materials that help stimulate the immune system.
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Scientists discover key protein that enables ‘shock & kill’ strategy for HIV latent virus clearance
Researchers have identified a specific gene transcription factor, BRD9, as a potential key to unlocking the mechanisms behind HIV-1 latency.
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Scientists decipher HIV-1 transcription initiation and elongation from single-molecule imaging data
Scientists have developed a dual-driven framework based on single-molecule imaging data and stochastic dynamic modeling to infer HIV-1 transcription dynamics.
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Antibiotics taken during pregnancy may reduce preterm births
A study of almost 1000 pregnant women in Zimbabwe found that a daily dose of a commonly used, safe and inexpensive antibiotic may have led to fewer babies being born early.
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Multiple testing for infectious diseases among migrants key to cutting onward transmission
Routine testing for multiple infectious diseases among migrants will benefit healthcare systems by identifying key infections earlier, a new study finds.
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HIV discovery could open door to long-sought cure
Scientists have uncovered a key reason why HIV remains so difficult to cure: Their research shows that small changes in the virus affect how quickly or slowly it replicates, and how easily or stubbornly it can reawaken from hiding.
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New diagnostic tool uses bioluminescence to detect viruses
Researchers are shining a powerful new light into the viral darkness with the development of Luminescence CAscade-based Sensor (LUCAS), a rapid, portable, highly-sensitive diagnostic tool for processing complex biological samples.
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Portable HIV monitoring device shows promise for remote settings
A newly developed microfluidic biosensor promises to reshape how CD4+ T cells — key indicators of immune function in Human Immunodeficiency Virus (HIV) patients — are detected.
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The Global Fund to fight AIDS, Tuberculosis and Malaria ‘should step up efforts’
The international community must protect global responses to HIV, tuberculosis (TB), and malaria to serve humanity’s collective interests, according to a new opinion article.
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Two HIV vaccine trials show proof of concept for pathway to broadly neutralizing antibodies
A new study combining data from two separate phase 1 clinical trials shows that a targeted vaccine strategy can successfully activate early immune responses relevant to HIV, and, in one trial, further advance them.
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Proof of concept for HIV vaccination that deploys germline-targeting
For a preventative HIV-vaccine to work it should induce broadly neutralising antibodies against all the diverse strains of the virus. The first in-human assessment of germline-targeting strategy with a trimer displays positive results.
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‘Loop’hole: HIV-1 hijacks human immune cells using circular RNAs
In a groundbreaking discovery, researchers have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body’s natural defenses and use it to support its survival and replication.
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Scientists win award for bringing breakthrough HIV treatment lenacapavir into play
Three people have been awarded the AAAS Mani L. Bhaumik Breakthrough of the Year Award for their work on the first HIV drug to offer long-lasting protection from infection — eliminating the need for people to take a daily pill.