All HIV articles
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News
New study determines incidence of and risk factors for hepatitis C virus reinfection among men with HIV
A new study provides new perspectives on transmission of hepatitis C virus (HCV), a virus that infects the liver and can be transmitted during injection of drugs, among men who have sex with men (MSM).
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News
Exploratory analysis associates HIV drug abacavir with elevated cardiovascular disease risk in large global trial
Current or previous use of the antiretroviral drug (ARV) abacavir was associated with an elevated risk of major adverse cardiovascular events (MACE) in people with HIV, according to an exploratory analysis from a large international clinical trial primarily funded by the National Institutes of Health (NIH). There ...
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Breakthrough study seeks functional cure for HIV
Researchers in George Mason University’s Center for Infectious Disease Research (CIDR) and Tulane National Primate Research Center conducted a breakthrough proof-of-concept study in Nature’s Gene Therapy that found an HIV-like virus particle that could cease the need for lifelong medications. Source: Photo by Evan Cantwell/Office of University Branding/George ...
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Long-acting injectable cabotegravir for HIV prevention is safe in pregnancy
Long-acting injectable cabotegravir (CAB-LA) was safe and well tolerated as HIV pre-exposure prophylaxis (PrEP) before and during pregnancy in the follow-up phase of a global study.
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Isolated viral load test may generate false positive results for people using long-acting PrEP
A single laboratory-based HIV viral load test used by U.S. clinicians who provide people with long-acting, injectable cabotegravir (CAB-LA) HIV pre-exposure prophylaxis (PrEP) did not reliably detect HIV in a multi-country study.
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HIV vaccines tested in PrEPVacc fail to reduce infections
The results of the PrEPVacc HIV vaccine trial conducted in Eastern and Southern Africa, which ran between 2020 and 2024, show that neither of the two experimental vaccine regimens tested reduced HIV infections among the study population.
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Panel issues first guidelines to prevent anal cancer in people with HIV
Results from a national study have informed the first guidelines at the federal level in the United States to detect and treat anal cancer precursor lesions in people with HIV to reduce the risk of developing anal cancer.
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Llama nanobodies deliver breakthrough in building HIV immunity
Scientists have developed a new antibody therapy that can neutralize a wide variety of HIV-1 strains. They found success in an unlikely source — llamas.
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New lab test to detect persistent HIV strains in Africa may aid search for cure
A multinational team has developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa—a vital tool in the search for an HIV cure that will benefit patients around the world.
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Midwest Center for AIDS Research to help end regional HIV epidemic
Researchers plan to establish the Midwest Developmental Center for AIDS Research. The center, slated to open in September, will aim to create a platform for researchers and public health workers to collaborate and coordinate their efforts to fight the HIV epidemic.
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Features
Infection, immunity and the One Health response in Indonesia
Infectious diseases (IDs) are a major health issue in Indonesia, as in many tropical low- and middle-income countries (LMICs), placing a significant economic burden on limited resources. Vaccination may have a critical role to play in the prevention of zoonotic infectious diseases.
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Survey finds many have misconceptions about sexually transmitted infection risk
Sexually transmitted infections (STIs) are on the rise in the U.S., including an 80% increase in syphilis over a five-year period, but a new survey finds many Americans have misconceptions on how STIs are spread and who should be treated.
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Syphilis cases are rising, but many people don’t know the symptoms
Syphilis cases are on the rise around the globe, but many Americans don’t know the symptoms. Just over half know that a case of syphilis can be permanently cured and most either mistakenly think there is a vaccine to prevent it or are unsure.
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New HIV reporter model: Visualizing HIV viral dynamics in cells with dual fluorescence
Researchers have developed a novel viral reporter system that allows for real-time visualization of HIV dynamics post-viral infection. HIV-Tocky features dual fluorescence to illuminate the process of provirus silencing and reactivation.
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USF selected as the international headquarters of the Global Virus Network
The University of South Florida will serve as host for the international headquarters of the Global Virus Network, a distinguished organization comprised of virologists spanning in excess of 80 Centers of Excellence and Affiliates in more than 40 countries.
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Novel vaccine concept generates immune responses that could produce multiple types of HIV broadly neutralizing antibodies
Using a combination of cutting-edge immunologic technologies, researchers have successfully stimulated animals’ immune systems to induce rare precursor B cells of a class of HIV broadly neutralizing antibodies (bNAbs). The findings, published in Nature Immunology, are an encouraging, incremental step in developing a preventive HIV vaccine. ...
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Researchers deliver boost for HIV vaccine research
Scientists have developed a comprehensive platform for HIV vaccine research capable of both preclinically validating next-step boost immunogens and providing new insights into the basic biology of the antibody response.
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A trial HIV vaccine triggered elusive and essential antibodies in humans
An HIV vaccine candidate triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.
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Advances in priming B cell immunity against HIV pave the way to future HIV vaccines, new studies show
Scientists have made several advances in the design of a class of HIV vaccines that could offer broad protection against the virus, according to four new research papers published this week.
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Scientists trace source and spread of HIV variant in Indonesia
A new study traces where the dominant HIV variant in Indonesia came from and how it spread from there, offering insights of possible value to the development of treatments against the disease.