All HIV articles – Page 4
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Gut microbiome can increase risk and severity of HIV and EBV disease
Researchers have shown that the microbiome has a significant impact on the acquisition of Epstein-Barr virus (EBV) and human immunodeficiency virus-1 (HIV) infection and plays a role in the course of disease.
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Scientists discover broadly neutralizing antibodies that contribute to HIV control
Researchers have investigated and revealed how neutralizing antibodies, including those described as broadly neutralizing, contribute to HIV control.
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New HIV drug formulation could improve treatment outcomes for children worldwide
Researchers have confirmed the dosing, safety and effectiveness of a drug formulation designed for treating children with human immunodeficiency virus (HIV).
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Key gene for resistance to HIV replication found in people of African ancestry
Scientists have identified a novel region in the genome that is only variable in populations of African ancestries and provided evidence that the gene CHD1L acts to limit HIV replication in a subset of white blood cells.
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Researchers create total synthesis of HIV replication inhibitor
Scientists appear to have discovered a way to produce a true structure of the rare but naturally-occurring anti-HIV compound Lancilactone C from start to finish.
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Jak inhibitors can decay viral reservoir in people with HIV
New research demonstrates the potential of Jak inhibitors, specifically ruxolitinib, to significantly decay the viral reservoir in people with HIV, offering a novel pathway toward long-term remission or a cure.
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Microbiologist and virologist creating Global Pandemic Research Alliance
Columbia University virologist Professor David Ho and The University of Hong Kong (HKU) microbiologist Professor Kwok-yung Yuen are teaming up to create a global alliance for conducting research in emerging infectious diseases.
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Digital test directly measures HIV viral load
Researchers have developed a time and cost-efficient digital assay that can directly measure the presence of HIV in a single drop of blood.
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Reactivation compound could be latest weapon against HIV
A research team has identified a molecular compound that activates latent HIV-1 in cells, showing promise for HIV treatments.
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New research shows HIV can lie dormant in the brain
Researchers in the UNC School of Medicine extracted living brain tissue to conclude that specialized immune cells in the brain can harbour latent but replication-competent HIV.
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Penile HIV infection is effectively prevented by antiretroviral treatment
Researchers have developed a new approach for the detailed evaluation of HIV infection throughout the entire male genital tract.
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England on track to end new HIV transmissions by 2030
New HIV transmissions in England have fallen by almost a third since 2019, according to an update on the HIV Action Plan for England.
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Test tube immune system IDs protein candidates for HIV vaccine
Scientists have developed a technique to find protein fragments that best stimulate the immune system to recognize and attack the virus.
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Protein may pave way to eliminating HIV latency
Researchers have identified and characterized Schlafen 12 (SLFN 12) as a novel HIV restriction factor that shuts down viral protein production and helps virus-infected cells to escape from anti-HIV therapy and immune responses.
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HIV targeted with novel dual gene-editing approach
Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection, new research shows.
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Researchers ID plant-based compound that inhibits reactivation of the HIV viral reservoir
Researchers have zeroed in on a promising compound that targets HIV reservoirs that persist in people living with HIV despite the presence of anti-HIV therapy.
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Study outlines world’s third successful cure of HIV infection after stem cell transplantation
The ‘Düsseldorf patient’, a 53-year-old man, is now the third person in the world to be completely cured of HIV with a stem cell transplant.
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Clinicians ID severe form of mpox with high mortality in people with advanced HIV
An international collaboration of clinicians has identified a severe, necrotising form of mpox with a high mortality in immunosuppressed people living with HIV.
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HIV vaccine candidate aims to block virus before it takes root
The National Institutes of Health has awarded $3.8 million to Texas Biomedical Research Institute to further develop a promising HIV vaccine candidate that stops the virus upon entry, before it begins rapidly spreading throughout the body.
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Scientists find two separate reservoirs of latent HIV in patients
Scientists have shown that, addition to HIV’s ability to lay dormant in the blood/lymphoid system, the virus may also lay dormant in the central nervous system, delineating another challenge in creating a cure.