All HIV articles – Page 10
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News’Dormant’ HIV produces RNA and proteins during anti-retroviral therapy
Two independent groups of researchers report that a subset of ‘dormant’ HIV-infected cells spontaneously produce HIV RNA and proteins that may impact patients’ HIV-specific immune responses.
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NewsTwo autopsies reveal secrets of HIV reservoirs
A research team shows for the first time that HIV reservoirs are concentrated in the spleen and lymph nodes, and that they can travel throughout the body.
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NewsBlood cancer drug shows promise in killing ‘silent’ HIV cells
An existing blood cancer drug has shown promise in killing ‘silent’ HIV cells and delaying reinfections – a significant pre-clinical discovery that could lead to a future cure for the disease.
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NewsTests of new antifungal therapy for fungal meningitis are successful
Researchers have successfully tested a new oral formulation of the antifungal medication amphotericin among people who had HIV and cryptococcal meningitis - a common fungal infection around the brain.
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NewsGut microbiome can increase risk and severity of HIV and EBV disease
Researchers have shown that the microbiome has a significant impact on the acquisition of Epstein-Barr virus (EBV) and human immunodeficiency virus-1 (HIV) infection and plays a role in the course of disease.
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NewsScientists discover broadly neutralizing antibodies that contribute to HIV control
Researchers have investigated and revealed how neutralizing antibodies, including those described as broadly neutralizing, contribute to HIV control.
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NewsNew HIV drug formulation could improve treatment outcomes for children worldwide
Researchers have confirmed the dosing, safety and effectiveness of a drug formulation designed for treating children with human immunodeficiency virus (HIV).
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NewsKey gene for resistance to HIV replication found in people of African ancestry
Scientists have identified a novel region in the genome that is only variable in populations of African ancestries and provided evidence that the gene CHD1L acts to limit HIV replication in a subset of white blood cells.
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NewsResearchers create total synthesis of HIV replication inhibitor
Scientists appear to have discovered a way to produce a true structure of the rare but naturally-occurring anti-HIV compound Lancilactone C from start to finish.
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NewsJak inhibitors can decay viral reservoir in people with HIV
New research demonstrates the potential of Jak inhibitors, specifically ruxolitinib, to significantly decay the viral reservoir in people with HIV, offering a novel pathway toward long-term remission or a cure.
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NewsMicrobiologist and virologist creating Global Pandemic Research Alliance
Columbia University virologist Professor David Ho and The University of Hong Kong (HKU) microbiologist Professor Kwok-yung Yuen are teaming up to create a global alliance for conducting research in emerging infectious diseases.
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NewsDigital test directly measures HIV viral load
Researchers have developed a time and cost-efficient digital assay that can directly measure the presence of HIV in a single drop of blood.
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NewsReactivation compound could be latest weapon against HIV
A research team has identified a molecular compound that activates latent HIV-1 in cells, showing promise for HIV treatments.
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NewsNew research shows HIV can lie dormant in the brain
Researchers in the UNC School of Medicine extracted living brain tissue to conclude that specialized immune cells in the brain can harbour latent but replication-competent HIV.
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NewsPenile HIV infection is effectively prevented by antiretroviral treatment
Researchers have developed a new approach for the detailed evaluation of HIV infection throughout the entire male genital tract.
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NewsEngland on track to end new HIV transmissions by 2030
New HIV transmissions in England have fallen by almost a third since 2019, according to an update on the HIV Action Plan for England.
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NewsTest tube immune system IDs protein candidates for HIV vaccine
Scientists have developed a technique to find protein fragments that best stimulate the immune system to recognize and attack the virus.
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NewsProtein may pave way to eliminating HIV latency
Researchers have identified and characterized Schlafen 12 (SLFN 12) as a novel HIV restriction factor that shuts down viral protein production and helps virus-infected cells to escape from anti-HIV therapy and immune responses.
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NewsHIV targeted with novel dual gene-editing approach
Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection, new research shows.
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NewsResearchers ID plant-based compound that inhibits reactivation of the HIV viral reservoir
Researchers have zeroed in on a promising compound that targets HIV reservoirs that persist in people living with HIV despite the presence of anti-HIV therapy.