All HIV articles
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NewsExposing a hidden anchor for HIV replication
Scientists investigating HIV have revealed a previously unknown role for the viral protein integrase, which helps HIV insert itself into human DNA. A new study provides the first direct evidence that integrase plays a critical structural role earlier on in HIV’s life cycle — when the virus matures into an infectious force.
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NewsHIV antibody opens up new approaches for vaccine development and combination therapies
An international research team has identified a novel HIV antibody that targets the virus at a particularly vulnerable site and overcomes previous limitations of known antibodies. The study opens up new perspectives for the development of vaccines and therapeutics against HIV-1.
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New vaccine platform promotes rare protective B cells
Based on a virus-like particle built with a DNA scaffold, the approach could generate broadly neutralizing antibody responses against HIV or influenza.
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NewsScientists demonstrate first-ever single-shot HIV vaccine neutralization success
Scientists have developed an HIV vaccine candidate that achieves something never before observed in the field: inducing neutralizing antibodies against HIV after a single immunization in nonhuman primates.
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NewsSepsis study IDs simple ways to save lives in Africa
Tuberculosis (TB) is a major unrecognized cause of deadly sepsis among people with HIV in Africa, a new study reveals. It found that more than half of the hundreds of patients enrolled in the study had TB and that immediate treatment increased their chances of survival significantly.
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NewsLithium study yields insights in the fight against HIV
Lithium, a widely used treatment for bipolar disorder and other mood disorders, has shown early promise in suppressing HIV. A new study found lithium can prevent infected cells from reactivating, and that it does so through an unexpected biological mechanism.
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NewsTB and HIV treatments are not enough for a full recovery
Existing treatments control TB and HIV, but the immune system does not revert to normal, helping explain why people living with HIV remain susceptible to infections and underscoring the need for immunotherapies.
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NewsReal-world data gives Africa a smarter path to fighting HIV and TB
African biostatisticians have offered a powerful, data-driven alternative that can accurately inform HIV policy, reduce healthcare costs, and save more lives.
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NewsResearchers see dramatic drop in HIV-infected immune cells in patient after cancer treatment received
Researchers report they may have taken an early step toward a more practical HIV cure. They focused on a patient undergoing cancer treatment and also living with HIV, who after receiving chemotherapy, had a significant reduction in the number of CD4+ T immune cells that contained an HIV provirus.
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NewsA testing paradox for sexually transmitted infections
Surveillance evidence shows an increase in people infected with other STIs after initiating PrEP. A new study provides a counterintuitive explanation revealing a testing paradox: even when the observed cases increase, the true numbers of STIs can decrease.
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NewsNew test distinguishes vaccine-induced false positives from active HIV infection
A new device correctly identified those with active HIV-1 infection 95% of the time and those without active infection but with vaccine-induced molecules that could trigger a false positive, 98% of the time.
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NewsCommon water pill may help HIV medicines work faster and reduce inflammation, early study suggests
Adding a readily available diuretic to standard HIV therapy appears to reduce circulating virus by four-fold, a new study shows. Researchers treated HIV-infected mice with human immune cells with first‑line antiretroviral therapy plus a long‑acting form of spironolactone.
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NewsA molecule opens a breach in HIV, providing access to its reservoirs
An international team has unveiled how a molecule capable of opening the “shell” of HIV improves the elimination of infected cells. The study demonstrates how a new CD4-mimetic compound, CJF-III-288, modifies the HIV envelope protein structure to allow for a better immune response.
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NewsResearchers identify why some people with HIV achieve remission after antibody treatment
Researchers have discovered why some people living with HIV who are given broadly neutralizing anti-HIV antibodies (bNAbs) can safely stop taking standard, lifelong HIV medications and maintain control of the virus for years, while others given the same treatment do not achieve this remission.
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NewsTreatment and prevention of HIV/AIDS: infectious disease experts talk unfinished business
As the world marks World AIDS Day, world-renowned infectious disease expert Anthony Fauci, MD, and Greg Folkers, MS, MPH, highlight advances made in the treatment and prevention of HIV, but caution ’History will judge us harshly should we squander this opportunity’.
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NewsLong-term HIV control: Could this combination therapy be the key?
A new study shows it may be possible to control HIV without long-term antiviral treatment — an advance that points the way toward a possible cure for a disease that affects 40 million people around the world.
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NewsNew prevention tools and investment in services essential in the fight against AIDS
On World AIDS Day, the World Health Organization (WHO) calls on governments and partners to rapidly expand access to new WHO-approved tools including lenacapavir (LEN) to drive down infections and counter disruption to essential health services caused by cuts to foreign aid.
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NewsHalf of all people living with HIV in Europe are diagnosed late
Europe is failing to test and treat HIV early, with over half of all diagnoses in 2024 being made too late for optimal treatment, according to new data from ECDC and WHO/Europe.
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NewsNew guideline on pre-exposure and postexposure HIV prevention
Multiple pre-exposure (PrEP) and postexposure (PEP) treatments are now available to prevent HIV infection. An updated Canadian guideline contains 31 recommendations and 10 good practice statements to help clinicians and other health care professionals offer these options to patients.
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NewsCuring hepatitis C can rebalance immunity in Indonesians living with HIV
A new study provides the first longitudinal immunological data on HIV/HCV-coinfected individuals in Southeast Asia, underscoring the importance of early hepatitis C treatment to prevent long-term immune and liver complications.