All HIV articles – Page 2
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Long-acting HIV treatment benefits adults with barriers to daily pill taking and adolescents with suppressed HIV
Long-acting, injectable antiretroviral therapy (ART) suppressed HIV replication better than oral ART in people who had previously experienced challenges taking daily oral regimens and was found safe in adolescents with HIV viral suppression.
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Children surpass a year of HIV remission after treatment pause
Four children have remained free of detectable HIV for more than one year after their antiretroviral therapy (ART) was paused to see if they could achieve HIV remission.
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Long-acting HIV treatment demonstrates efficacy in people with challenges taking daily medicine as prescribed
Long-acting antiretroviral therapy (ART) with cabotegravir and rilpivirine was superior in suppressing HIV replication compared to daily oral ART in people who had been unable to maintain viral suppression through an oral daily regimen, according to interim data from a randomized trial. Source: NIAID Colorized transmission electron micrograph ...
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Uptake of HIV prevention medication doubles with mix of digital health interventions
A combination of interventions of one-on-one telehealth coaching, peer support forums, and automated text messages more than doubled the use of the HIV prevention strategy, called PrEP, among younger, at-risk Americans.
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Droughts may trigger HIV transmission increase among women in rural sub-Saharan Africa
Droughts have the potential to increase the spread of HIV for women living in rural parts of Africa, researchers at the University of Bristol have found.
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PD-1-enhanced DNA vaccine achieves 6-year cART-free AIDS prevention and virologic control
Researchers have found that PD-1-enhanced DNA vaccination can induce sustained virus-specific CD8+ T cell immunity in an AIDS monkey model.
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Researchers are using RNA in a new approach to fight HIV
Scientists have developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.
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Research reveals how lenacapavir pushes HIV capsid to breaking point
Researchers have uncovered the details of how the novel drug lenacapavir works to stop the virus in its tracks. The molecular mechanisms that they uncovered could help to refine and design more effective anti-viral therapies.
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New trial highlights incremental progress towards a cure for HIV-1
A new clinical trial suggests that a combination of the drug vorinostat and immunotherapy can coax HIV-infected cells out of latency and attack them.
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Study reveals accelerated aging in women living with HIV
Women with HIV experience accelerated DNA aging, a phenomenon that can lead to poor physical function, according to a new study.
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Scientists spot an ultra-fast movement on surface of HIV virus
Investigators catch ultra-fast HIV docking mechanism in the act, giving them a new handle on the surface of the virus that could lead to broadly neutralizing antibodies for an AIDS vaccine.
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Simulations show how HIV sneaks into the nucleus of the cell
A new study has revealed how HIV squirms its way into the nucleus as it invades a cell.
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Researchers pinpoint most likely source of HIV rebound infection
Researchers used genetic sequencing techniques on the nonhuman primate version of HIV to identify that lymph nodes in the abdomen are the main source of rebound infection after the first week of stopping antiretroviral treatment.
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HIV ‘secret handshake’ helps it reach cell’s centre to kickstart infection
New research reveals how the HIV capsid gets into the nuclear pore barrier channel.
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Scientists identify window of opportunity for treatment promoting HIV remission
Starting treatment four weeks after infection with HIV promotes long-term control of the virus following the interruption of treatment after two years of antiretroviral therapy.
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HIV antibodies protect animals in proof-of-concept study
Three different HIV antibodies each independently protected monkeys from acquiring simian-HIV (SHIV) in a placebo-controlled proof-of-concept study intended to inform development of a preventive HIV vaccine for people.
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Anti-HIV drugs may prevent complications from bacterial sepsis
A new study suggests that reverse transcriptase inhibitors — antiretroviral drugs also used to manage HIV infections — can be used to prevent inflammatory complications of bacterial sepsis.
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Priming vaccine tested by global project lays path to HIV vaccine
A global project is attemptng to discover a HIV vaccine based on germline targeting and that is practical for those in Low and Middle-Income Countries.
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Smallpox vaccine induces immunity against monkeypox infection in people living with HIV
Researchers have shown that intradermal vaccination with the JYNNEOS vaccine against smallpox is the best option to protect people living with HIV from contracting the monkeypox virus.
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Higher viral load during HIV infection can shape viral evolution
A new paper finds that HIV populations in people with higher viral loads also have higher rates of viral recombination.