All Microbiological Methods articles
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NewsBreakthrough in human norovirus research: Researchers overcome major obstacle to grow and study the virus
Researchers have overcome a major obstacle that limited their ability to continuously grow human norovirus. They identified factors that restrict viral replication and developed a way to overcome them to optimize long-term viral cultivation.
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NewsTesting menstrual blood for HPV could be “robust alternative” to cervical screening
Testing menstrual blood for human papillomavirus (HPV) could be a “robust alternative or replacement” for current cervical cancer screening by a clinician, finds a study. The researchers say using menstrual blood for HPV testing is convenient and non-invasive.
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NewsYeast cells can be used for rapid testing of cancer immunotherapy
An international research team has developed a new yeast-based biotechnological platform that makes it possible to test and understand advanced cancer treatments much faster and cheaper than before. It can reduce development time for new types of cancer immunotherapy from months to days or weeks.
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NewsGreen chemistry: Friendly bacteria can unlock hidden metabolic pathways in plant cell cultures
Co-culturing plant cells with harmless bacteria can expand the diversity of obtainable plant-derived compounds for pharmaceuticals, cosmetics, and agrochemicals, a new study shows.
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NewsNew tool shows how to enter and change pneumocystis fungi
Researchers have reported success in genetically modifying the fungal pathogen Pneumocystis murina. Their approach uses extracellular vesicles from mouse lungs to deliver gene-modifying molecules inside the fungal cells. The modified fungus expressed the introduced genomic modifications.
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NewsHow genes influence the microbes in our mouths
A new study has found human genetic factors that influence the oral microbiome and may increase risk of cavities and tooth loss in some people. Analysis of the now largest collection of oral microbiome profiles reveals interactions between human and bacterial DNA.
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NewsTracking antibiotic resistance in the environment gets a high tech upgrade
Antibiotic resistance is often framed as a hospital problem, but a growing body of evidence shows that the environment plays an equally critical role in the global spread of drug resistant bacteria. Rivers, soils, wastewater, and even the air can act as reservoirs for antibiotic resistance genes that may eventually ...
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NewsScientists illuminate ancient plant-fungus partnership at molecular level
Researchers have coupled two powerful tools that allow scientists to identify which proteins work together to make plant-fungi partnerships function—and to verify those interactions in living plant roots, where the collaboration actually occurs.
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NewsPIXL Max: Automated colony picker breaks records for speed and accuracy
With the latest innovation from the team at Singer Instruments, a new standard for speed and repeatability in microbial colony pickers has been achieved through the integration of cutting edge AI technologies.
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NewsScientists engineer quantum-enabled proteins, opening a new frontier in biotechnology
A new study reports the creation of a new class of biomolecules, magneto-sensitive fluorescent proteins, that can interact with magnetic fields and radio waves. This is enabled by quantum mechanical interactions within the protein, and occur when it is exposed to light of an appropriate wavelength.
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NewsSeawater microbes offer new, non-invasive way to detect coral disease, study finds
Researchers have discovered that microorganisms in seawater surrounding corals provide a powerful indicator of coral disease, potentially transforming how reef health is monitored worldwide.
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NewsHuman nasal passages defend against the common cold and help determine how sick we get
Researchers demonstrate how the cells in our noses work together to defend us from the common cold and suggest that our body’s defense to rhinovirus—not the virus itself—typically predicts whether or not we catch a cold, as well as how bad our symptoms will be.
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NewsGolden Gate method enables rapid, fully-synthetic engineering of therapeutically relevant bacteriophages
Researchers have described the first fully synthetic bacteriophage engineering system for Pseudomonas aeruginosa. In this method, researchers engineer bacteriophages synthetically using sequence data rather than bacteriophage isolates.
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NewsExploring metabolic noise opens new paths to better biomanufacturing
Engineers investigating fluctuating metabolic activity in microorganisms have developed tools to keep every microbial cell at peak productivity during biomanufacturing.
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NewsEarly intervention of cyanobacterial risks starting from the genome?
A new study proposes using “~3 Mbp” as a threshold to establish a genome size-oriented proxy indicator for cyanobacterial risk early warning.
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NewsNew study explores therapeutic potential of CRISPRCas3 genome-editing system
Scientists working on the genetic disease transthyretin amyloidosis evaluated the efficacy of the CRISPR–Cas3 system in safely achieving a permanent reduction of transthyretin (TTR) production through genome editing of the TTR gene.
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NewsBirding enthusiasts can help songbirds avoid salmonella epidemics
Biologists are developing a tool to predict when deadly salmonella outbreaks are likely to happen in wild songbird populations so that people can protect their feathered friends by taking down bird feeders at the right time.
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NewsA gentler way to model deadly lung infections in old age
Researchers report a refined mouse model that successfully mimics chronic Pseudomonas aeruginosa lung infection in old age. The study introduces an agar bead-based delivery strategy that allows bacteria to persist in the lungs of aged mice without causing rapid death.
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NewsFrom palm oil to designer enzymes: researchers reprogram yeast cells
Many everyday products contain fatty acids from palm oil or coconut oil, but the extraction of these raw materials is associated with massive environmental issues. Researchers have now developed a biotechnological approach that could enable a more environmentally friendly production method.
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NewsChanges in genetic structure of yeast lead to disease-causing genomic instabilities
Researchers studying a yeast model have discovered that the loss of heterochromatin can kickstart genetic changes, potentially resulting in the development of diseases like cancer.