All Microbiological Methods articles
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News Ribosome profiling identifies thousands of new viral protein-coding sequences
With the help of a technique called Massively Parallel Ribosome Profiling (MPRP), scientists have identified more than 4000 open reading frames (ORFs) across 679 human-associated viral genomes.
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NewsCultured mini-organs reveal the weapons of aggressive Shigella bacteria
Thanks to lab-grown miniature intestines, researchers have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured human mini-organs to investigate a wide range of other serious infections.
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NewsScholars take a new look at controversial Stateville prison malaria research 75 years ago
Medical ethicists are shining a light on a buried part of the malaria research conducted on inmates at Illinois’ Stateville Penitentiary 75 years ago.
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NewsDrone-based tech deployed to detect subtle signs of rice blast disease
Scientists have developed a novel vegetation index—the Rice Blast Index (RBI)—using drone-based hyperspectral remote sensing technology, to rapidly and non-invasively detect subtle signs of rice blast disease and achieve precise field management.
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NewsLight-controlled bacteria can tackle antibiotic resistance or become ‘bacterial robots’
A groundbreaking technique uses light-sensitive materials to control bacteria, allowing them to sense light and convert light energy into electrical signals across their membranes without the need for any genetic modification.
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NewsStudy resolves diatom tree of life - and could offer clues to Earth’s puzzle
A new study finds that diatoms evolved slowly for the first 100 million years of their existence. Then, 170 million years ago, they reached an inflection point characterized by a burst of rapid speciation orders of magnitude faster than anything that had preceded it.
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NewsNew cell-sorting platform accelerates discovery of high-value microbes
Researchers have developed an advanced, high-throughput single-cell sorting platform that enables direct isolation of living cells with targeted metabolic profiles from large mutant libraries.
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NewsReal-time 3D visualization of leech peptide reveals potent antibacterial and antibiofilm activity
Researchers have discovered a novel natural antimicrobial peptide, ‘Hirunipin-2,’ from the salivary glands of the medicinal leech using cutting-edge imaging technology, demonstrating that it has high potential as a new therapeutic effective against superbacteria.
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NewsDNA floating in the air tracks wildlife, viruses — even drugs
A new study reveals the power of DNA, vacuumed up from the air, which can track everything from elusive bobcats to illicit drugs. A simple air filter running for hours, days or weeks can pick up signs of nearly every species that grows or wanders nearby.
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NewsAffordable real-time sensor system for algal bloom detection
Engineers have developed a real-time, low-cost algal bloom monitoring system utilizing inexpensive optical sensors and a novel labeling logic. The system achieves higher accuracy than state-of-the-art AI models such as Gradient Boosting and Random Forest.
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NewsNew microscope harnesses bioluminescence to bring glowing cells into focus
Researchers have developed a new microscope that significantly improves how bioluminescent signals in living cells can be observed. The system, known as QIScope, is built around a highly sensitive camera technology capable of detecting extremely low levels of light.
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CareersHow structural imaging is revolutionising vaccines
Dr. Peijun Zhang, Director of the Electron Bio-Imaging Centre (eBIC) at the UK’s national synchrotron facility Diamond Light Source, reveals how Cryo-ET is powering some of the most important advances in vaccine research.
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NewsOrganoids reveal the secrets of bat immunity
Researchers successfully infected both bat organoids and human airway organoids with the Marburg virus. Compared to the human models, bat organoids exhibited a significantly higher baseline antiviral immune activity even before infection.
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NewsCool science: Researchers craft tiny biological tools using frozen ethanol
Imagine drawing on something as delicate as a living cell — without damaging it. Researchers have made this groundbreaking discovery using an unexpected combination of tools: frozen ethanol, electron beams and purple-tinted microbes.
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NewsSeawater microbes are powerful tool for diagnosing coral reef health and strengthening conservation efforts
Microorganisms in the water surrounding coral reefs provide valuable insights on the health state of reefs and surrounding ocean. Sampling and analyzing reef water microbes can be done in a variety of ways ranging in cost and complexity, adding to their usability.
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NewsWorld’s largest bat organoid platform paves the way for pandemic preparedness
Researchers have created the world’s most comprehensive bat organoid platform. These ’mini-organs’ are grown from five common bat species found across Asia and Europe and represent four different organs—airway, lungs, kidneys, and small intestine.
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NewsCombining laboratory techniques yields wealth of information about deadly brain tumors
In a new study, researchers injected into the tumor a virus aimed at killing glioblastoma cells. Surgeons took tumor tissue samples and ran them through multiple advanced laboratory techniques to demonstrate that even small tissue samples can yield additional insights.
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NewsResearchers reveal lipid-based communication between body and gut microbes
A new study shows how a host protein can specifically recognize bacterial lipids, thus triggering beneficial immune responses. It also highlights a new way the body actively shapes the gut microbiome by communicating with microbes to maintain balance.
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NewsStudy uncovers why so many microbes fail to grow in the lab
Many microorganisms die when attempts are made to cultivate them. A new study suggests that that their survival does not depend solely on the needs of individual microbes but on a hidden web of relationships that can be caused to collapse by even small structural changes.
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NewsScientists ID previously unknown enzymes that can produce potentially antimicrobial agents
Micro-organisms generate potential agents for combating bacteria and fungi. Researchers have identified and optimized enzymes that can specifically generate a certain functional group of these natural substances, expanding the toolkit of potential agents.