All Pharmaceutical Microbiology articles – Page 35
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NewsResearch uncovers a new path to drug diversity
By exploring protein evolution, scientists have found new “fusion sites” that enable faster and more targeted drug development.
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NewsResearchers invent artificial intelligence model to design new superbug-fighting antibiotics
Researchers have invented a new generative artificial intelligence model which can design billions of new antibiotic molecules that are inexpensive and easy to build in the laboratory.
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NewsTeardrops target multiple COVID variants through the twist in the spike protein
Particles that gum up the keys that the virus uses to enter cells could one day be an effective COVID treatment whenever vaccines and other treatments fall short.
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NewsDrug candidate may ‘unmask’ latent HIV-infected cells, mark them for destruction
Scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.
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NewsDaff-derived Alzheimer’s drug fermented with help from AI and bacteria moves closer to reality
An innovative approach uses artificial intelligence and biosensors to pave the way for faster drug development.
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NewsLongitudinal gut fungal alterations and potential fungal biomarkers for the progression of primary liver disease
Scientists have found that during liver disease progression, the abundance of Chytridiomycota increased initially, but was later replaced by Ascomycota in HCC.
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NewsNew bioengineered protein design shows promise in fighting COVID-19
Researchers have designed a novel protein capable of binding to the spike proteins found on the surface of the coronavirus, allowing them identify and recognize the virus for diagnostic purposes, and to hinder its ability to infect human cells.
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NewsInsights into release of fungal toxin promise progress in treating infections
The toxin Candidalysin of the yeast Candida albicans is incorporated into an unusual protein structure during an infection, and researchers have now succeeded in deciphering the function of this unusual arrangement.
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NewsRevolutionary chronic wound treatment could help millions
A team of scientists has developed an effective treatment for preventing infection in chronic wounds involving the plasma (electrical gas) activation of hydrogel dressings to produce a unique mix of different chemical oxidants.
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NewsSteroid drugs used for HRT can combat E. coli and MRSA
New research has revealed that a class of steroid drugs currently used in hormone replacement therapy (HRT) can also stop the growth of antibiotic-resistant E. coli and effectively kill MRSA.
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NewsNew dual therapeutic strategy shows promise against multidrug-resistant salmonella
A new collaborative study discloses the discovery and application of a new therapeutic strategy to target the multidrug-resistant bacterium Salmonella enterica in vivo, with promising results. The results were published in Scientific Reports. Source: CDC/ Antibiotic Resistance Coordination and Strategy Unit Medical illustration of drug-resistant, nontyphoidal Salmonella sp. ...
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NewsResearchers open new leads in anti-HIV drug development, using a compound found in nature
Researchers have successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.
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NewsLong-acting HIV treatment benefits adults with barriers to daily pill taking and adolescents with suppressed HIV
Long-acting, injectable antiretroviral therapy (ART) suppressed HIV replication better than oral ART in people who had previously experienced challenges taking daily oral regimens and was found safe in adolescents with HIV viral suppression.
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NewsFirst atom-level structure of packaged viral genome reveals new properties, dynamics
A computational model of the more than 26 million atoms in a DNA-packed viral capsid expands our understanding of virus structure and DNA dynamics, insights that could provide new research avenues and drug targets, researchers report.
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NewsDrug-resistant tuberculosis responds rapidly to bedaquiline-based second-line therapy
Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens.
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NewsSpace-grown antiviral drug successfully brought back to earth in private Varda Space capsule
Space-grown crystals of an antiviral drug have been brought to earth following the successful recovery of the capsule from Varda Space Industries’ W-1 mission.
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NewsResearchers develop molecules for a new class of antibiotics that can overcome drug resistant bacteria
A new class of antibiotics not only shows promise against a broad array of bacterial infections but can also evade the dreaded resistance that has been rendering our current generation of first-line antibiotics ineffective.
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NewsLong-acting HIV treatment demonstrates efficacy in people with challenges taking daily medicine as prescribed
Long-acting antiretroviral therapy (ART) with cabotegravir and rilpivirine was superior in suppressing HIV replication compared to daily oral ART in people who had been unable to maintain viral suppression through an oral daily regimen, according to interim data from a randomized trial. Source: NIAID Colorized transmission electron micrograph ...
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NewsLow-cost microbe can speed biological discovery
Researchers have created a new version of a microbe to compete economically with E. coli – a bacteria commonly used as a research tool due to its ability to synthesize proteins – to conduct low-cost and scalable synthetic biological experiments.
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News£1.8m grant to engineer microbial cell factories
A team of academics from Aston University and the University of Warwick has secured a £1.8m grant to engineer microbial cell factories to produce membrane proteins which will support future drug screening and sustainable chemical production.