All Pharmaceutical Microbiology articles – Page 31
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NewsScientists uncover molecular basis of how potential anti-Covid drug binds to viral N-glycan
Researchers evaluating the potential of naturally occurring pradimicin A (PRM-A) as a new anti-SARS-CoV-2 drug that suppresses SARS-CoV-2 transmission investigated how exactly PRM-A binds to the viral N-glycans.
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CareersConnecting with microbiologists and presenting research: Oluwole Owoyemi reports back from ASM 2024
Medical microbiologist Oluwole Owoyemi of Achievers University Owo and Federal University of Technology, Akure, reports back from ASM MICROBE 2024 after being awarded a Scientific Event Travel Grant by Applied Microbiology International.
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NewsCancer drug could be repurposed to fight Covid-19
Twelve years ago, cancer researchers identified a molecule that helps cancer cells survive by shuttling damaging inflammatory cells into tumor tissue. In new research, they show that the same molecule does the same thing in lung tissue infected with COVID-19.
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NewsScientists unravel life-saving effect of dexamethasone in COVID-19
Researchers have discovered how the cortisone compound dexamethasone influences the impaired inflammatory response to Covid-19 and which patients benefit from it.
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NewsTreatment with a mixture of antimicrobial peptides can impede antibiotic resistance
A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a viable strategy for new antibiotic treatments.
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NewsCoumarin glycosides reverse enterococci-facilitated enteric infections
Researchers have developed a dietary therapeutic for enterococci-mediated infections.
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NewsResearchers harness intratumoral microbiome against colorectal cancer
Scientists have established a microbiota-targeted drug delivery system that exhibits high efficiency in colorectal cancer targeting and colon retention.
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NewsResearchers deploy E coli to selectively target tumor cells
Scientists explore how an engineered bacterium limits tumor growth and maximizes targeted anticancer drug delivery.
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NewsAI helps mine genetic elements from ancient genomes to tackle antibiotic resistance
Scientists have developed an artificial intelligence tool to mine the vast and largely unexplored biological data—more than 10 million molecules of both modern and extinct organisms— to discover new candidates for antibiotics.
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NewsBacteria discovery leads to novel probiotic for eczema
Research has led to the availability of a new over-the-counter topical eczema probiotic, based on the discovery that bacteria present on healthy skin called Roseomonas mucosa can safely relieve eczema symptoms in adults and children.
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NewsNovel method for synthesis of coral-derived compound offers hope for non-toxic fouling agents
Researchers have developed a novel total synthesis method for scabrolide F, a natural compound derived from corals, and revealed its antifouling properties.
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NewsMarine natural product derivative offers new therapeutic strategy to inhibit enterovirus A71 replication
Researchers revealed that the inhibition of enterovirus A71 (EV-A71) replication can be achieved by targeting the human coatomer subunit zeta-1 (COPZ1) using a marine natural product derivative known as MPA-CF3.
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NewsDiagnostic stewardship approach to C. diff reduces unnecessary testing
Revised rules for when Clostridioides difficile tests could be ordered helped to reduce inappropriate testing by 20%, which in turn can help rein in the overtreatment of patients.
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NewsNovel 3D hydrogel culture to study TB infection and treatment
Researchers have designed a novel 3D hydrogel culture system that mimics the mammalian lung environment, providing a platform to track and study how tuberculosis bacteria infect lung cells and test the efficacy of therapeutics used to treat TB.
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NewsScientists identify molecules associated with recurrence in blood samples from malaria patients
Researchers have described for the first time possible biomarkers associated with recurrence of vivax malaria. The study involved analysis of blood samples from volunteers infected by Plasmodium vivax.
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CareersMike Goodfellow: a passion for Actinobacteria and an outstanding mentor
Applied Microbiology International has paid tribute to Professor Mike Goodfellow, who died on March 8 2024 at the age of 83 following a short illness.
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NewsMetformin and AGIs show potential for improved outcomes in COVID-19 patients with type 2 diabetes
A new study has found a significant association between metformin and AGI use and reduced all-cause mortality in COVID-19 patients with Type 2 diabetes. Conversely, insulin use was linked to an increased risk of death.
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NewsWild chimpanzees seek out medicinal plants to treat illness and injuries
The study combined behavioral observations of wild chimpanzees (Pan troglodytes) with pharmacological testing of the potentially medicinal plants they eat.
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NewsE. coli sends out SOS when antibiotics attack, sparking emergency mode
Antibiotics damage E. coli DNA, including by causing formation of single strands of incomplete DNA inside the cell. When that happens, it’s like lighting a match under a smoke detector, according to a new study.
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NewsWHO releases report on state of development of antibacterials
Although the number of antibacterial agents in the clinical pipeline increased from 80 in 2021 to 97 in 2023, there is a pressing need for innovative agents for serious infections and to replace those becoming ineffective due to widespread use, the WHO says.