All Pharmaceutical Microbiology articles – Page 28
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NewsTests of new antifungal therapy for fungal meningitis are successful
Researchers have successfully tested a new oral formulation of the antifungal medication amphotericin among people who had HIV and cryptococcal meningitis - a common fungal infection around the brain.
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CareersI was transformed into a cartoon scientist honey bee!
Professor Les Baillie of Cardiff University has had a few unique experiences as a microbiologist, but becoming one of the stars of Betsy and Bertie Save The Bees is one that earned particular kudos from his granddaughter.
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NewsMolnupiravir dose of human effect size-equivalent blocks Covid transmission in ferrets
Two oral drugs provide equivalent therapeutic benefit in preventing severe COVID-19 in animal models, but only molnupiravir efficiently blocked SARS-CoV-2 transmission when administered at a human effect size-equivalent dose.
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NewsMonoclonal antibody shows promise for treating chronic hepatitis B and D infections
In a preclinical study, the potential of an engineered investigational human monoclonal antibody for the treatment of chronic hepatitis B and hepatitis D has been demonstrated.
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NewsChanges in gut microbiome alters rewarding effects of cocaine and cravings
Scientists have provided the first evidence that changes in the gut microbiome have significant effects on cocaine use and cravings after withdrawal.
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NewsNew HIV drug formulation could improve treatment outcomes for children worldwide
Researchers have confirmed the dosing, safety and effectiveness of a drug formulation designed for treating children with human immunodeficiency virus (HIV).
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News Researchers discover method to overcome antimicrobial resistance
Scientists have found a new class of molecules that inhibit the efflux pump of a bacterial cell.
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NewsScientists develop new solid-state storage method for biological materials
Scientists have developed a novel method for storing biological materials such as RNA and proteins in a solid-state, physically resembling a pill or a tablet, which dissolves in water for on-demand use.
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NewsResearchers uncover novel bacterial communication system to combat AMR
Using a sophisticated mass spectrometry technology developed at SMART and MIT, researchers have discovered that the enzyme RlmN is a stress sensor for reactive oxygen species (ROS) – highly reactive molecules which can cause damage to bacteria. Source: SMART AMR (L to R) SMART researchers Dr Cui Liang, ...
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NewsBioengineered yeast devouring agricultural waste could close carbon circle
Researchers report making modified yeast that can feed on a wider range of materials, many of which can be derived from agricultural by-products that we don’t use known as waste biomass.
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NewsPicolinic acid reveals its broad-spectrum antiviral abilities
Picolinic acid, a natural compound produced by mammalian cells, can block several disease-causing viruses such as SARS-CoV-2 and influenza A viruses, according to a new study.
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NewsFuture medicines could feature ingredients targeting bacterial motility and chemotaxis
Future medicines will probably be made up of a cocktail of compounds that inhibit different bacterial targets, including some that act against their motility and chemotaxis mechanisms, a new review suggests.
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NewsCyanotriazole compounds can rapidly cure trypanosome infections in mice
Scientists have identified a class of cyanotriazoles (CTs), which exhibit potent trypanocidal activity and lead to rapid clearance of parasites both in vitro and in mouse models of Chagas disease and human African trypanosomiasis.
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NewsAI model can accelerate development of new antivirals
Researchers have shown that IBM’s AI Model, MoLFormer, can generate antiviral molecules for multiple target virus proteins, including SARS-CoV-2, that can accelerate the drug discovery process.
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NewsResearchers can use ultrasound to control orientation of small particles, including bacteria
Using ultrasound technology and a nozzle, scientists have separated, controlled and ejected different particles based on their shape and various properties, with implications for drug delivery and bioprinting.
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NewsHeart drug peruvoside could prevent spread of up to 12 viruses
Peruvoside, a plant-based compound that is commonly used to treat heart failure, has been discovered to be able to prevent up to 12 medically important viruses, all originating from different virus families.
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NewsSingle hepatitis E mutation renders sofosbuvir therapy ineffective
A single mutation of the hepatitis E virus has been shown to cause treatment with the hepatitis C drug sofosbuvir to become much less effective, according to a study that provides new insights for future drug development.
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NewsUnravelling Coenzyme Q10 pathway could pave way to industrial production
Scientists have unravelled part of the Coenzyme Q10 biosynthetic pathway in Agrobacterium tumefaciens, paving the way to enhancing the bacterium so that it can produce the probiotic on an industrial scale.
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NewsBiological clocks of people and malaria parasites tick in tune
Research could pave the way to new anti-malarials that work by ’jet-lagging’ the parasites that cause the disease.
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NewsDrugs pipeline rife with strategies to combat MRSA
A host of new antimicrobial strategies are in the development pipeline that could provide hope for healthcare sectors battling multi-drug resistant Staphylococcus aureus infections.