All Pharmaceutical Microbiology articles – Page 23
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NewsUncovering the shield: gene duplication behind antifungal resistance in Madurella fahalii
Researchers used advanced genetic and biomolecular chemistry tools to uncover why itraconazole treatment fails against Madurella fahalii but not other Madurella species.
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NewsCan gut microbes save patients from chemotherapy side effects?
Intestinal microbes that survive chemo can rid the gut of excess chemo drugs and produce a vitamin that helps to stem nausea, a new study reveals.
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NewsBiosynthetic pathway discoveries mean we can halve the price of costly cancer drug
Researchers have identified the enzymes responsible for the two critical final steps in the biosynthetic pathway that makes the chemotherapy drug Taxol active as a drug, potentially opening it up to biotech based production.
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NewsResearchers reveal how microbes can swim without a brain
Many microorganisms can move in a goal oriented way in liquids, despite the lack of a complex nervous system. New research explains the behaviour of microorganisms, and could also enable nanobots to move in a targeted manner.
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NewsCommon drugs can help viruses spread
JAK inhibitors are often prescribed for autoimmune diseases and inflammatory conditions such as rheumatoid arthritis, but scientists have found they also weaken the body’s natural defences against viruses.
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NewsCombining laboratory techniques yields wealth of information about deadly brain tumors
In a new study, researchers injected into the tumor a virus aimed at killing glioblastoma cells. Surgeons took tumor tissue samples and ran them through multiple advanced laboratory techniques to demonstrate that even small tissue samples can yield additional insights.
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NewsNew hope against superbugs: Promising antibiotic candidate discovered
An international team of researchers has discovered saarvienin A, a new type of glycopeptide antibiotic. Their findings introduce a compound with strong activity against highly resistant bacterial strains.
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NewsScientists evaluate in-vitro activity of ceftazidime-avibactam against carbapenem-resistant gram-negative bacteria
Scientists explored the in-vitro activity of ceftazidime-avibactam (CAZ-AVI) in clinical isolates of carbapenem-resistant gram-negative bacteria collected at the outpatient, emergency, and inpatient departments of the Indus Hospital, Karachi.
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NewsFirst all-oral treatment for a rare but deadly strain of sleeping sickness now available
A handful of patients in Ethiopia, Malawi, Tanzania, Zambia, and Zimbabwe, as well as foreign travellers, have now been treated with a medicine that is revolutionizing care for patients with rhodesiense sleeping sickness.
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NewsProbiotic supplementation may help reduce chemotherapy side effects in breast cancer
A new study shows that probiotics with seven strains have a potential effect in patients with breast cancer, especially in the improvement of common chemotherapy-related side effects such as fatigue and nausea.
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NewsSelf-assembly of a large metal-peptide capsid nanostructure through geometric control
Controlling the topology and structure of entangled molecular strands is a key challenge in molecular engineering. This new hollow dodecahedral shell demonstrates remarkable stability and potential for functionalization and encapsulating macromolecules.
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NewsScientists win award for bringing breakthrough HIV treatment lenacapavir into play
Three people have been awarded the AAAS Mani L. Bhaumik Breakthrough of the Year Award for their work on the first HIV drug to offer long-lasting protection from infection — eliminating the need for people to take a daily pill.
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NewsSpiritual healing sites could be linked to antibiotic-producing microorganisms
A study by AMI member Dr Gerry Quinn highlights the potential of spiritual healing sites as fertile ground for novel antibiotics, particularly from Streptomyces bacteria, known for producing the majority of current antibiotics.
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NewsSilver nanoparticles produced by fungus could be used to prevent and treat COVID-19
Silver nanoparticles produced by the fungus Trichoderma reesei could become important allies in the prevention and treatment of COVID-19. Tests on hamsters showed that they not only inhibited the infection but also reduced the viral load in the lungs.
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NewsScientists introduce new engineered drug candidate for Mycobacterium abscessus to save lives
Scientists have introduced a promising drug candidate engineered to target a deadly and emerging infection. They took a hyper-detailed look into the problem of Mycobacterium abscessus, and chemically re-engineered a widely-used rifamycin antibiotic.
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NewsA digestive ‘treasure chest’ shows promise for targeted drug treatment in the gut
A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments.
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NewsA symbiotic gut fungus wards off liver disease in mice
Researchers have found a new ally in the fight against a serious liver disease: a symbiotic gut-dwelling fungus that produces a molecule shown to be capable of reversing disease progression in mice.
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NewssiRNA plus nanovaccine yields stable functional cure for chronic hepatitis B
Researchers have developed an innovative therapy for chronic hepatitis B, synergistically combining their proprietary ferritin nanoparticle-preS1 (Ferritin-NP-preS1) therapeutic vaccine with a preclinically validated HBV-specific siRNA.
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NewsCutting off parasite’s energy supply could help fight malaria
Once inside the body of an infected person, the malaria parasite relies on a process called glycolysis to produce energy and stay alive. Blocking the enzymes involved in this process could cut off the parasite’s primary energy source and kill it.
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NewsFungi dwelling on human skin may provide new antibiotics
Researchers have uncovered a molecule produced by yeast living on human skin that showed potent antimicrobial properties against a pathogen responsible for a half-million hospitalizations annually in the United States.