All Pharmaceutical Microbiology articles – Page 20
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NewsRevealed: New vaccine target to block malaria transmission
Researchers have visualised a key protein complex in malaria parasites for the first time, uncovering a new target for next-generation vaccines that could help stop the disease from spreading.
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NewsAnti-neuroinflammatory natural products from isopod-related fungus now accessible via chemical synthesis
Herpotrichone is valued for its ability to suppress inflammation in the brain and protect nerve cells, but could only be obtained in minute quantities from fungi that are symbiotic with isopods. Researchers have succeeded in chemically synthesizing this rare natural product.
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NewsNew drug combo outperforms Tamiflu in fighting flu (and chocolate is the key)
Scientists have unveiled a new drug pairing - including a compound found in chocolate - that outperforms Tamiflu, the most widely used anti-influenza medication, against even the deadliest flu strains, including avian and swine flu.
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NewsResearchers debunk long-standing concern about flu treatment in children
Researchers have debunked a long-standing theory about oseltamivir, known as Tamiflu. Oseltamivir treatment during flu episodes was associated with a reduced risk of serious neuropsychiatric events, such as seizures, altered mental status and hallucination.
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NewsWhy killer cells can lapse into ‘exhausted’ CD8+ T cells that no longer can stem disease
In a detailed study of exhausted T cell subsets researchers show that a transcriptional repressor called Gfi1 is a key regulator of the subset formation of exhausted CD8+ T cells and may offer a key to reducing exhaustion.
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NewsResearchers develop bacterial cellulose-based dressing for advanced burn wound care
Scientists have developed an innovative bacterial cellulose (BC)-based hemostatic dressing that enables rapid and sustained bleeding control.
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NewsScientists pinpoint optimal dose of methylprednisolone for treating severe Mycoplasma pneumoniae pneumonia
Investigators have compared the efficacy of low- versus high-dose of methylprednisolone in preventing pulmonary lesions in children with severe Mycoplasma pneumoniae pneumonia.
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NewsLavender steps up as a natural preservative in skin-care emulsions
A new study shows that blends of lavender essential oil and hydrosol can replace synthetic preservatives in oil-in-water creams, cutting microbial counts by >99 % without irritating skin.
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NewsClinical trial finds safe, effective treatment for children with severe post-Covid syndrome
Researchers have discovered that a drug designed to treat Celiac disease supported a more rapid return to normal activities for patients following COVID. A small, randomized clinical trialfound the oral drug larazotide was both safe and effective in treating children with MIS-C.
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NewsNew tool helps predict antibiotic resistance
Researchers have developed a platform that identifies drug resistance genes already circulating in the environment before they emerge in the clinic and directly couples this information to the design of resistance-evasive antibiotics.
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NewsNew AI tool accelerates mRNA-based treatments for viruses, cancers, genetic disorders
A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various cell types.
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NewsInappropriate prescriptions for antibiotics, glucocorticoids and opioids common at urgent cares
Urgent care visits commonly result in inappropriate prescriptions of antibiotics, glucocorticoids or opioids, researchers have warned.
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NewsCan a compound produced by deep-sea bacteria treat cancer?
Investigators purified a long-chain sugar molecule, or exopolysaccharide, from deep-sea bacteria and demonstrated that it triggers pyroptosis—an inflammatory form of programmed cell death—to inhibit tumor growth.
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NewsFermented stevia leaf extract has potential as anticancer treatment, researchers find
Stevia may provide more benefits than as a zero-calorie sugar substitute. When fermented with bacteria isolated from banana leaves, stevia extract kills off pancreatic cancer cells but doesn’t harm healthy kidney cells, according to a research team.
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NewsBacteria from cows show promising results in treating MRSA infections
Cows carry a bacterium, Staphylococcus simulans, that could become an effective weapon against increased antibiotic resistance. Signaling molecules from this bacterium can treat infections caused by MRSA bacteria as effectively as antibiotics.
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NewsPenicillin allergy testing needed to fight antibiotic resistance
Removing incorrect penicillin allergy labels on GP records could combat antibiotic resistance and save lives, an NIHR-funded clinical trial has found.
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NewsResearchers uncover the antiviral potential of defensins
Scientists have discovered that certain defensins - tiny proteins with powerful antimicrobial potential - could block the virus that causes COVID-19 (SARS-CoV-2) from entering human cells.
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NewsAI finds hundreds of potential antibiotics in snake and spider venom
Researchers used a deep-learning system to sift through a database of more than 40 million venom encrypted peptides (VEPs). In a matter of hours, the algorithm flagged 386 compounds with the molecular hallmarks of next-generation antibiotics.
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NewsEmerging viral threats combatted by a potent new dual lipid kinase inhibitor
Lipid kinases play a critical role in cell signalling and membrane trafficking by phosphorylating lipid molecules in the body. The inhibition of two of these lipid kinases, PIKfyve and PIP4K2C, could be beneficial in the treatment of diseases, particularly emerging viruses.
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NewsScientists discover compounds that help cells fight a wide range of viruses
Researchers have identified compounds that can fight off viral infection by activating a defense pathway inside host cells. These compounds, they believe, could be used as antiviral drugs that work against not just one but any kind of virus.