All Reproductive &Urinary Tract Microbiome articles
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Scientists uncover the microbial connection between urinary bladder and vagina
A new study highlights the association between urinary and vaginal pathogenic Escherichia coli in recurrent cystitis in postmenopausal women.
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Rapid test for UTI wins $10m Longitude Prize on AMR to transform fight against superbugs
Sysmex Astrego’s PA-100 AST System has won the $10m (£8m) Longitude Prize on AMR. The winning test provides accurate antibiotic susceptibility results in 45 minutes – compared to the 2-3 day wait patients currently face.
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Study suggests hepatitis E may be a sexually transmitted infection
Discovering that hepatitis E virus is associated with sperm in pigs suggests the virus may be both sexually transmitted and linked to male infertility, according to a new study.
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Virus that causes COVID-19 can remain in sperm for 110 days after infection
Researchers detected SARS-CoV-2 in male reproductive cells under the microscope even when PCR testing failed to detect the virus in semen. The discovery serves as a warning of possible implications for natural conception and assisted reproduction.
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Human cervix modeled in microfluidic organ chip helps target bacterial vaginosis
Engineered cervix with in vivo-like mucus production, hormone sensitivity, and associated microbiome creates novel testbed for bacterial vaginosis therapeutics and other treatments.
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Specific microbial hallmarks in vagina could indicate gynecological cancers
A new study demonstrates unique vaginal microbiome in patients with gynecological cancers which could function as a biomarker.
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Sperm can adapt to sexually transmitted microbes
Researchers have discovered that the function of sperm, technically called male fertility, adapts to sexually transmitted microbes.
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Study sheds light on bacteria associated with pre-term birth
Researchers have found that multiple species of Gardnerella, bacteria sometimes associated with bacterial vaginosis (BV) and pre-term birth, can coexist in the same vaginal microbiome.
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Birth by C-section more than doubles odds of measles vaccine failure
Researchers say it is vital that children born by caesarean section receive two doses of the measles vaccine for robust protection against the disease.
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How E. coli get a foothold to cause urinary tract infections
New research examines how the bacteria Escherichia coli—responsible for most UTIs—is able to use host nutrients to reproduce at an extraordinarily rapid pace during infection despite the near sterile environment of fresh urine.
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Source of pregnancy complications from infections revealed by placenta map
The first panoramic view of infection pathways in the human placenta has been created, which could highlight potential drug targets to develop pregnancy-safe therapies for malaria, toxoplasmosis and listeria.
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Women need better treatments for bacterial vaginosis: call
Researchers at the University of Maryland School of Medicine are calling for robust studies for a treatment already used in Europe.
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Father’s gut microbes affect the next generation
A study shows that disrupting the gut microbiome of male mice increases the risk of disease in their future offspring.
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Gut microbiome continually evolves as pregnancy progresses
A new study reveals the patterns of microbial dysbiosis associated with different pregnancy complications, providing an theoretical basis for elucidating the baseline characteristics of the microbiome in pregnant women.
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Major genetic meta-analysis reveals how antibiotic resistance in babies varies according to mode of birth, prematurity, and where they live
Meta-analysis of genetic studies from 10 countries finds infants born by C-section have more antibiotic resistance genes; antibiotic use and prematurity also fuel resistance.
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Insights into release of fungal toxin promise progress in treating infections
The toxin Candidalysin of the yeast Candida albicans is incorporated into an unusual protein structure during an infection, and researchers have now succeeded in deciphering the function of this unusual arrangement.
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Zika vaccine safe, effective when administered during pregnancy
A vaccine against Zika virus is safe and effective when administered both before and during pregnancy, according to new research.
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Antibiotic is cost-saving treatment for reducing maternal sepsis in developing countries
New findings suggest that giving an oral dose of azithromycin to pregnant women who deliver vaginally is a cost-saving treatment for reducing maternal sepsis, death or infection in developing countries.
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Gut microbiome changes during pregnancy may influence immune system response
During pregnancy, changes in levels of cytokines - immune system proteins important in inflammation - may be linked to specific alterations in the mother’s gut microbiome and in plasma and fecal metabolites.
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Semen microbiome health may impact male fertility
The semen microbiota might play a crucial role in influencing sperm parameters and enhancing male fertility, a new study suggests.