All tuberculosis articles
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NewsDesigning self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.
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NewsNeutrophil-to-lymphocyte ratio and its correlation with tuberculosis infection
A new study reveals a significant negative correlation between neutrophil-to-lymphocyte ratio (NLR) and the risk of tuberculosis infection (TBI), particularly in males and individuals with hypertension.
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NewsStudy calls for better measures of poverty to strengthen tuberculosis research
A new review examines existing methods for assessing socioeconomic status in TB studies and highlights their shortcomings. The authors call for better, standardized poverty metrics to improve research and policy.
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NewsNovel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.
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NewsAI accelerates the search for new tuberculosis drug targets
A novel biotechnology was developed to utilize artificial intelligence (AI) as a high-throughput way to identify more effective antimicrobial candidates to treat the multi-drug resistant Mycobacterium tuberculosis and understand their underlying modes of action.
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NewsStudy finds three new safe, effective ways to treat drug-resistant tuberculosis
An international clinical trial has found three new safe and effective drug regimens for tuberculosis that is resistant to rifampin, the most effective of the first-line antibiotics used to treat TB.
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FeaturesBridging the gap: mouse breath research to advance infectious disease diagnostics
The role of VOCs in health and disease is garnering increasing attention, particularly in their use as biomarkers for a wide range of medical conditions.
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NewsTB or not TB? A new clinician decision support tool for tuberculosis
A risk assessing tool was recently developed to evaluate the likelihood of tuberculosis (TB) infections using previous patient data with or without TB. Such clinical decision support tool would allow safer and more efficient patient deisolation procedures and ensure smoother clinician workflows.
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NewsWHO calls on Trump to reconsider order that USA will withdraw from the Organization
The World Health Organization has said it regrets President Donald Trump’s announcement that the United States of America intends to withdraw from the Organization.
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NewsDecoding the WHO Global Tuberculosis Report 2024: A critical analysis of global and Chinese key data
A new paper provides an in-depth interpretation of the WHO Global Tuberculosis Report 2024, analyzes global TB trends, updates the status of drug-resistant TB, discusses the intersection between TB and HIV, and summarizes the implications of the pandemic on TB control efforts.
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NewsSystem to auto-detect new variants will inform better response to future infectious disease outbreaks
Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans - including those causing flu, COVID, whooping cough and tuberculosis.
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NewsPeat-bog fungi produce substances that kill tuberculosis-causing bacteria
An analysis of fungi collected from peat bogs has identified several species that produce substances toxic to the bacterium that causes the human disease tuberculosis.
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NewsUnderstanding neonatal infectious diseases in low- and middle-income countries
Researchers have conducted an in-depth study on the epidemic status, secular trends, and risk factors of 15 common neonatal infectious diseases across low- and middle-income countries (LMICs) from 1990 to 2019.
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NewsRule-breaking tuberculosis bacteria challenge growth norms
The rod-shaped tuberculosis (TB) bacterium is the first single-celled organism ever observed to maintain a consistent growth rate throughout its life cycle, a new study reports, hinting at why the pathogen so readily outmaneuvers our immune system and antibiotics.
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NewsResearchers reveal why a key tuberculosis drug works against resistant strains
Research has uncovered why a relatively new antibiotic for tuberculosis (TB) works against multidrug-resistant strains, potentially inspiring improved treatments and drug development strategies.
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NewsStudy identifies ‘Achilles heel’ of drug-resistant pathogens
A study has found a highly vulnerable weakness in drug-resistant Mycobacterium tuberculosis, using a genetic platform to identify biological pathways in a drug-resistant strain of the bacterium that are highly sensitive to inhibition.
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NewsResearchers seek out shorter, simpler TB treatments
Scientists are working to develop treatment options for tuberculosis that require fewer pills, shorter treatment periods (ideally 2-3 months), and consist of 3-4 medications that reduce the risk of resistance while minimizing toxicity.
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News10% of children in high-burden tuberculosis settings may develop the disease by age 10
A new study finds a high risk of tuberculosis infection and disease in children up to 10 years old who live in areas where TB spread is common.
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NewsTuberculosis changes liver metabolism and could promote diabetes
Scientists have discovered that tuberculosis disrupts glucose metabolism in the body and can promote progress to diabetes.
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NewsBetter use of vaccines could reduce antibiotic use by 2.5 billion doses annually, says WHO
A new report finds that vaccines against 24 pathogens could reduce the number of antibiotics needed by 22% or 2.5 billion defined daily doses globally every year, supporting worldwide efforts to address antimicrobial resistance (AMR).