All tuberculosis articles
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New findings on TB could change how we treat inflammatory disorders
Researchers have found rare mutation that leaves its carriers much more likely to become ill with TB—but, curiously, not with other infectious diseases, potentially upending long-held assumptions about the immune system.
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Immune protection against tuberculosis reinfection driven by cells that dampen lung inflammation
The body’s first line of defense against tuberculosis (TB) involves immune cells that suppress lung inflammation instead of activating it, scientists report.
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NIH grant establishes UAB’s Global Research Resource for Human Tuberculosis
A $5.8m grant led by Adrie Steyn, Ph.D., of the University of Alabama at Birmingham and the Africa Health Research Institute, or AHRI, in Durban, South Africa, will provide user-requested infected human lung tissue and analytical services to tuberculosis researchers worldwide.
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study highlights factors associated with higher tuberculosis risk in South Africa
Tuberculosis is the world’s top infectious killer. About 10 million people fall ill with the disease every year, and roughly 1.5 million people die because of it, according to the World Health Organization. Additionally, about one-quarter of the world’s population is infected with the disease’s causative agent Myctuberobacterium tuberculosis. ...
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Shared geographic origin of TB strain and human host could boost risk of infection
For some forms of tuberculosis, the chances that an exposed person will get infected depend on whether the individual and the bacteria share a hometown, according to a study comparing how different strains move through mixed populations in cities.
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Scientists ID ‘unconventional’ new pathway for TB vaccines
Marginal zone B (MZB) cells are a natural response to TB infection which has been long overlooked - and which might be a welcome new target.
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NIH funds consortium to accelerate development of new TB treatments
A new consortium has been awarded a five-year, $31 million grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to accelerate the development of faster, more effective treatment regimens for tuberculosis.
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Edited BCG offers potential vaccine to prevent tuberculosis in people of all ages
TB remains the leading cause of death by infectious disease globally, with South Africa having one of the highest incidence rates in the world. Source: Y tambe Apparatus for BCG vaccination - Kuchiki’s needle While the BCG vaccine used to prevent TB is widely available for infants, ...
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Scientists can now detect antibiotics in your fingerprints – aiding the fight against drug-resistant TB
A fingerprint may soon be all a doctor needs to check whether tuberculosis patients are taking their antibiotics – thanks to a new study. Scientists successfully detected the drugs in finger sweat – and with almost the same accuracy as a blood test.
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Global study reveals stark differences between females and males in major causes of disease burden
Globally, there are substantial differences between females and males (aged 10 and older) when it comes to health, with limited progress in bridging these health gaps over the past 30 years, according to a new study.
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Experts developing immune-enhancing therapies to target tuberculosis
Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body’s own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.
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Undernourished household members at increased risk for developing TB after exposure
Researchers have found that undernourished household contacts are three times more likely to progress to TB disease.
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Researchers uncover new reasons to target neutrophils for tuberculosis therapy
Using cell models of infection, scientists examined the cross-talk between two lung immune cells: the macrophage and the neutrophil.
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Tuberculosis can have a lasting impact on the lung health of individuals who have been successfully treated for the disease
New research has found compelling evidence that tuberculosis (TB) can have a lasting impact on the lungs of individuals who have been successfully treated for the disease.
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Collaboration garners new support to tackle high-value tuberculosis targets
A groundbreaking collaboration will combat global health challenges in tuberculosis through innovative technology.
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Study finds association between TB infection and increased risk of various cancers
A population-wide observational study shows an association between tuberculosis (TB) and cancer, with those with current or previous TB more likely to have a diagnosis of a variety of cancers.
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More than 18,000 excess TB cases in the U.S. attributable to structural racism
A robust analysis of national tuberculosis (TB) surveillance data found continuing, persistent disparities in TB incidence among U.S.-born racial and ethnic minorities, despite an overall decrease in cases observed during the analysis period.
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A combination of approved drugs enhances the delivery of anti-bacterial medications to treat tuberculosis
Scientists repurposed approved drugs that they originally tested to normalize blood vessels surrounding tumors to improve drug delivery to cancer cells.
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New enzymatic cocktail can kill tuberculosis-causing mycobacteria
A new study shows that an enzymatic cocktail can kill a variety of mycobacterial species of bacteria, including those that cause tuberculosis.
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Cancer therapies show promise in combating tuberculosis
A study has identified a combination of medications that may improve blood flow within granulomas, tight clusters of white blood cells formed by the body’s immune system in response to tuberculosis infection, benefiting drug delivery.