All tuberculosis articles
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NewsIn hard-to-treat form of tuberculosis, shorter, gentler therapy shows unequal benefit
A first-ever clinical trial exclusively conducted among people with a hard-to-treat form of tuberculosis known as pre-extensively drug-resistant TB shows many patients benefit from shorter, simpler regimens.
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NewsTB bacteria play possum to evade vaccines
Scientists studied how the TB bacterium evades an immune system primed to destroy it. Their genetic study in mice reveals that TB bacteria can essentially play dead to outlast the immune response.
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NewsNew breakthrough uncovers how to kill ‘zombie’ TB cells resistant to antibiotics
Researchers exposed a library of over 500,000 genetically modified tuberculosis bacteria to two commonly used antibiotics. By analysing the survivors, they pinpointed genes whose disruption significantly reduced the number of surviving persisters.
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NewsMultiple testing for infectious diseases among migrants key to cutting onward transmission
Routine testing for multiple infectious diseases among migrants will benefit healthcare systems by identifying key infections earlier, a new study finds.
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NewsStudy uncovers how certain antibodies help fight tuberculosis
Researchers collected the largest library of monoclonal antibodies to Mycobacterium tuberculosis (Mtb) and identified specific antibody features that significantly limit its growth.
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NewsBiologist examines growth patterns in bacteria to help develop more targeted, effective antibiotics
Among the new investigative projects at the University of Texas at Arlington is one headed by Dr. Cara Boutte, who is studying how certain bacteria grow by examining how they build their cell walls, an effort that could lead to the development of more effective antibiotics.
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NewsStudy discovers DNA switch that controls TB growth – and could help unlock its antibiotic resistance secrets
The bacteria that cause tuberculosis (TB) may have an ‘on-off switch’ that lets them pause and restart growth, according to a new study which helps explain why TB is so hard to treat with antibiotics and could pave the way for better drugs.
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NewsTuberculous meningitis: study shows that metabolism drives mortality
A new study suggests that dysregulated β-oxidation may be an important and potentially modifiable contributor to mortality in tuberculous meningitis.
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NewsThe Global Fund to fight AIDS, Tuberculosis and Malaria ‘should step up efforts’
The international community must protect global responses to HIV, tuberculosis (TB), and malaria to serve humanity’s collective interests, according to a new opinion article.
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NewsNew molecular label could lead to simpler, faster tuberculosis tests
Chemists have demonstrated that they can label a glycan called ManLAM using an organic molecule that reacts with specific sulfur-containing sugars. These sugars are found in only three bacterial species, including the microbe that causes TB.
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NewsA new smartphone-sized device can test for tuberculosis - here’s why that matters for children
Scientists have designed the first-of-its-kind portable device to deliver fast, low-cost TB results — no lab required — to fight the world’s deadliest infectious disease.
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NewsMolecular stool test could improve detection of tuberculosis in adults with HIV
A prospective multicentre study highlights the potential of the Xpert MTB/Ultra stool test for diagnosing tuberculosis in people living with HIV.
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NewsMany TB cases may have gone undetected in prisons in Europe and the Americas during COVID-19
A new study found that reported diagnoses for tuberculosis were consistently lower than expected throughout the pandemic, even though incarceration rates remained largely consistent.
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NewsTuberculosis in children and adolescents: EU/EEA observes a rise in 2023
The notification rate of tuberculosis (TB) went up from 2 to 2.5 per 100,000 population. But overall, numbers of notified paediatric cases remain relatively low across the region.
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NewsStudy discovers tuberculosis genes necessary for airborne transmission
Tuberculosis bacteria rely on a family of genes that help them survive the challenging journey from one person’s lungs to another person’s during coughing, sneezing or talking, according to a study that offers new targets for tuberculosis therapies.
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NewsDesigning self-destructing bacteria to make effective tuberculosis vaccines
Preclinical studies have demonstrated a more effective tuberculosis (TB) vaccine through engineering bacteria to self-destruct and swiftly stops the infection on cue, which activates a more robust immune response.
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NewsNeutrophil-to-lymphocyte ratio and its correlation with tuberculosis infection
A new study reveals a significant negative correlation between neutrophil-to-lymphocyte ratio (NLR) and the risk of tuberculosis infection (TBI), particularly in males and individuals with hypertension.
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NewsStudy calls for better measures of poverty to strengthen tuberculosis research
A new review examines existing methods for assessing socioeconomic status in TB studies and highlights their shortcomings. The authors call for better, standardized poverty metrics to improve research and policy.
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NewsNovel antibiotic BTZ-043 also reaches tuberculosis bacteria hiding in dead lung tissue
Researchers have shown that the novel antibiotic BTZ-043 effectively penetrates tubercolous lesions and accumulates there in high concentrations. Consequently, the drug can fight Mtb bacteria even in hard-to-reach areas.
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NewsAI accelerates the search for new tuberculosis drug targets
A novel biotechnology was developed to utilize artificial intelligence (AI) as a high-throughput way to identify more effective antimicrobial candidates to treat the multi-drug resistant Mycobacterium tuberculosis and understand their underlying modes of action.