All tuberculosis articles
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NewsInuit recommendations to address high rates of tuberculosis in Nunavik, Quebec
Tuberculosis rates for Inuit living in Nunavik, the Inuit lands in northern Quebec, are 1,000 times greater than among non-foreign-born Quebeckers, and underresourcing of local health care adds to hardship from the disease, found new research.
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NewsScientists develop therapeutic, nasally delivered DNA vaccine for tuberculosis
Research shows the vaccine — in combination with drug therapy — accelerated a relapse-free TB cure in mice, improved activity of a drug-resistant TB regimen and stimulated immune responses in nonhuman primates.
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NewsA study links armed conflict in Colombia with higher tuberculosis cases and mortality
Areas with the highest intensity of conflict between 2008 and 2019 recorded a higher disease burden, highlighting the need for control strategies tailored to each territory.
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NewsScreening and preventive treatment program reduced tuberculosis incidence 83% among Tibetan children living in northern India
A study shows that significant reduction of tuberculosis (TB) transmission and burden (the total impact of health problems on a population) among schoolchildren in high-burden areas can be achieved using existing TB screening, treatment and follow-up protocols.
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NewsWHO recommends new diagnostic tools to help end TB
On World TB Day, WHO is urging countries to accelerate action to end tuberculosis (TB) and expand access to lifesaving services by using new innovations such as diagnostic tests that can be used near the point-of-care and tongue swabs that can help detect the disease faster.
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NewsEuropean Region misses 1 in 5 TB cases: WHO Europe and ECDC publish new joint surveillance report
The European Region continues to fall short of regional and global End TB milestones on two fronts: a persistent detection challenge, with one in five TB cases going undiagnosed or unreported, and drug-resistance levels that remain far higher than in other regions.
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NewsStudy maps how tuberculosis bacteria power themselves
A new study provides the first detailed 3D structure of a protein called EtfD, which the bacterium Mycobacterium tuberculosis uses to extract energy from lipids (fats), along with the first laboratory test capable of directly measuring its activity.
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NewsTackling tuberculosis systematically: How the environment shapes TB risk
Researchers introduce the concept of the “tuberculogenic environment”: the complex interplay of structures, rules, and living conditions that keep certain communities at high TB risk, even when care is available.
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NewsRich medieval Danes bought graves ‘closer to God’ despite leprosy stigma, archaeologists find
Researchers used gravesites to investigate social exclusion based on illness, by studying whether people with leprosy or tuberculosis were kept out of the higher-status areas. Unexpectedly, they found that people who were ill with stigmatized diseases were buried just as prominently as their peers.
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NewsResearchers develop new inhalable treatment for TB
Researchers have developed an inhalable, immunomodulating, biocompatible nanoparticle system encapsulating rifampin, one of the most important TB drugs.
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NewsShorter treatment regimens are safe options for preventing active tuberculosis
A study comparing one- and three-month antibiotic treatments to prevent active tuberculosis (TB) finds that a high percentage of patients successfully completed both regimens and suffered few adverse side effects.
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NewsSepsis study IDs simple ways to save lives in Africa
Tuberculosis (TB) is a major unrecognized cause of deadly sepsis among people with HIV in Africa, a new study reveals. It found that more than half of the hundreds of patients enrolled in the study had TB and that immediate treatment increased their chances of survival significantly.
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NewsTB and HIV treatments are not enough for a full recovery
Existing treatments control TB and HIV, but the immune system does not revert to normal, helping explain why people living with HIV remain susceptible to infections and underscoring the need for immunotherapies.
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NewsReal-world data gives Africa a smarter path to fighting HIV and TB
African biostatisticians have offered a powerful, data-driven alternative that can accurately inform HIV policy, reduce healthcare costs, and save more lives.
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NewsNew one-two punch could knock out drug-resistant TB
Researchers found that pairing the antibiotic rifampicin with a second compound turned multidrug resistance into a weakness—providing proof of concept for using basic science to design life-saving dual-drug strategies.
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NewsCould hidden infections be fueling long COVID?
For millions suffering from long COVID, their persistent breathlessness, brain fog and fatigue remain a maddening mystery, but microbiologists think they may have cracked the case. The review argues that co-infections acquired before or during COVID could cause symptoms to persist indefinitely for many people.
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NewsTuberculosis: Scientists develop novel drug candidate for combating resistant pathogens
Researchers have developed a promising new substance for targeting bacteria that cause tuberculosis. The team have produced a compound that inhibits the pathogens’ ability to produce energy and causes them to die.
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News‘Creeping catastrophe’: Climate change is driving global rise in infectious diseases, leading health experts warn
Infectious diseases such as malaria, dengue, and tuberculosis are considered to pose as great a challenge to global health as new or emerging pathogens, according to a study. Participants reported that climate change, poverty, and drug resistance are combining to create an escalating health crisis.
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NewsPhase 2 clinical trial results show potential to shorten TB treatment time
New clinical trial results show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as “SPaL.”
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NewsScientists uncover tuberculosis bacterium’s ’heartbeat’, opening door to new treatments
Scientists have identified a molecular system inside Mycobacterium tuberculosis that functions like the organism’s heart or lungs, keeping it alive. The system, known as PrrAB, helps the bacterium generate energy and breathe. When researchers used a gene-silencing tool, the bacterium died.