All Antibiotics articles
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NewsMedications leave lasting mark on the gut microbiome, even years after use
Analysing stool samples and prescription records from over 2,500 Estonian Biobank participants, researchers found that the majority of drugs studied were linked to microbiome changes, with a substantial number of them also showing long-term effects detectable years after patients stopped taking them.
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NewsMethod probing dark matter uncovers hundreds of new bacteria, and two potential antibiotics
A new approach to exploring untapped soil resources circumvents the need to grow bacteria in the lab by extracting very large DNA fragments directly from soil to piece together the genomes of previously hidden microbes, and then mines resulting genomes for bioactive molecules.
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NewsA ‘universal’ therapy against the seasonal flu? Antibody cocktail targets virus weak spot
Researchers report that a cocktail of antibodies protected mice—including those with weakened immune systems—from nearly every strain of influenza tested, including avian and swine variants that pose pandemic threats.
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NewsNew antibiotic to fight superbug C. diff proves effective in clinical trial
As the effectiveness of antibiotics meant to fight the deadly superbug Clostridioides difficile wanes, a research team is seeing positive results of a new antibiotic on the scene – ibezapolstat – which is proving successful in fighting these infectious bacteria in clinical trials.
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NewsOne dose of antibiotic treats early syphilis as well as three doses
Researchers have found that a single injection of the antibiotic benzathine penicillin G (BPG) successfully treated early syphilis just as well as the three-injection regimen used by many clinicians. These findings from a late-stage clinical trial suggest the second and third doses of conventional BPG therapy do not provide a health benefit.
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NewsUnlocking how bacteria bounce back after antibiotics
A groundbreaking study has uncovered how Escherichia coli (E. coli) persister bacteria survive antibiotics by protecting their genetic instructions. The work offers new hope for tackling chronic, recurring infections.
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NewsResearchers use generative AI to design compounds that can kill drug-resistant bacteria
With help from artificial intelligence, researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).
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NewsStudy finds tiny microbes shape brain development
New research finds that microbes play an important role in shaping early brain development, specifically in a key brain region that controls stress, social behavior, and vital body functions.
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NewsTwo-dose therapy for S. aureus bloodstream infections on par with standard treatment
A clinical trial has found that the outcome of treating complicated Staphylococcus aureus bloodstream infections with two intravenous (IV) doses of the antibiotic dalbavancin seven days apart is just as good as daily IV doses of conventional antibiotics over four to six weeks.
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NewsAI uncovers new antibiotics in ancient microbes
Researchers used artificial intelligence to identify previously unknown compounds in Archaea that could fuel the development of next-generation antibiotics.
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NewsRegional differences in antibiotic use in newborns
There are relatively large regional differences in Sweden in the proportion of newborns receiving antibiotics for suspected sepsis, according to a study. The researchers want to call attention to overuse as well as highlight good examples.
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NewsNew tool helps predict antibiotic resistance
Researchers have developed a platform that identifies drug resistance genes already circulating in the environment before they emerge in the clinic and directly couples this information to the design of resistance-evasive antibiotics.
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NewsStudy of water bodies frequented by wild birds reveals presence of antimicrobial resistance genes in nine in 10 samples
The first UK study to monitor antimicrobial resistance and influenza viruses in water bodies has revealed that 92% of samples contained genes for resistance to colistin, an antibiotic of last resort.
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NewsInappropriate prescriptions for antibiotics, glucocorticoids and opioids common at urgent cares
Urgent care visits commonly result in inappropriate prescriptions of antibiotics, glucocorticoids or opioids, researchers have warned.
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NewsProbiotics can help or hinder gut recovery after antibiotic treatment
All probiotics are not created equal, according to new research. In a mouse model, researchers found that different probiotic strains can either accelerate or delay the gut microbiome’s recovery after antibiotic treatment.
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NewsHidden bacterial redundancy could be antibiotic game-changer
Staphylococcus aureus possesses a surprising level of metabolic redundancy, allowing it to survive even when key enzymes are knocked out, a new study finds. However, when two specific enzymes are removed, staph doesn’t infect its host as readily.
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NewsPenicillin allergy testing needed to fight antibiotic resistance
Removing incorrect penicillin allergy labels on GP records could combat antibiotic resistance and save lives, an NIHR-funded clinical trial has found.
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NewsBacteria gene discovery enhances key antibiotic production for farming and medicine
Monensin is a vital antibiotic used in agriculture and medicine. By analyzing the genome of Streptomyces cinnamonensis, the team discovered that specific genes (fadD, fadE, fadB, fadA) in the fatty acid degradation pathway significantly boost monensin synthesis.
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NewsAntibiotic resistance predicts higher mortality risk in 17-year follow-up
A population-based study finds that in addition to antibiotic use, diet, sex, living environment, income level and certain gut bacteria are associated with a higher burden of resistance.
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NewsAI finds hundreds of potential antibiotics in snake and spider venom
Researchers used a deep-learning system to sift through a database of more than 40 million venom encrypted peptides (VEPs). In a matter of hours, the algorithm flagged 386 compounds with the molecular hallmarks of next-generation antibiotics.