All Antibiotics articles
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NewsResearchers use generative AI to design compounds that can kill drug-resistant bacteria
With help from artificial intelligence, researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).
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NewsStudy finds tiny microbes shape brain development
New research finds that microbes play an important role in shaping early brain development, specifically in a key brain region that controls stress, social behavior, and vital body functions.
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NewsTwo-dose therapy for S. aureus bloodstream infections on par with standard treatment
A clinical trial has found that the outcome of treating complicated Staphylococcus aureus bloodstream infections with two intravenous (IV) doses of the antibiotic dalbavancin seven days apart is just as good as daily IV doses of conventional antibiotics over four to six weeks.
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NewsAI uncovers new antibiotics in ancient microbes
Researchers used artificial intelligence to identify previously unknown compounds in Archaea that could fuel the development of next-generation antibiotics.
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NewsRegional differences in antibiotic use in newborns
There are relatively large regional differences in Sweden in the proportion of newborns receiving antibiotics for suspected sepsis, according to a study. The researchers want to call attention to overuse as well as highlight good examples.
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NewsNew tool helps predict antibiotic resistance
Researchers have developed a platform that identifies drug resistance genes already circulating in the environment before they emerge in the clinic and directly couples this information to the design of resistance-evasive antibiotics.
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NewsStudy of water bodies frequented by wild birds reveals presence of antimicrobial resistance genes in nine in 10 samples
The first UK study to monitor antimicrobial resistance and influenza viruses in water bodies has revealed that 92% of samples contained genes for resistance to colistin, an antibiotic of last resort.
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NewsInappropriate prescriptions for antibiotics, glucocorticoids and opioids common at urgent cares
Urgent care visits commonly result in inappropriate prescriptions of antibiotics, glucocorticoids or opioids, researchers have warned.
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NewsProbiotics can help or hinder gut recovery after antibiotic treatment
All probiotics are not created equal, according to new research. In a mouse model, researchers found that different probiotic strains can either accelerate or delay the gut microbiome’s recovery after antibiotic treatment.
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NewsHidden bacterial redundancy could be antibiotic game-changer
Staphylococcus aureus possesses a surprising level of metabolic redundancy, allowing it to survive even when key enzymes are knocked out, a new study finds. However, when two specific enzymes are removed, staph doesn’t infect its host as readily.
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NewsPenicillin allergy testing needed to fight antibiotic resistance
Removing incorrect penicillin allergy labels on GP records could combat antibiotic resistance and save lives, an NIHR-funded clinical trial has found.
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NewsBacteria gene discovery enhances key antibiotic production for farming and medicine
Monensin is a vital antibiotic used in agriculture and medicine. By analyzing the genome of Streptomyces cinnamonensis, the team discovered that specific genes (fadD, fadE, fadB, fadA) in the fatty acid degradation pathway significantly boost monensin synthesis.
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NewsAntibiotic resistance predicts higher mortality risk in 17-year follow-up
A population-based study finds that in addition to antibiotic use, diet, sex, living environment, income level and certain gut bacteria are associated with a higher burden of resistance.
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NewsAI finds hundreds of potential antibiotics in snake and spider venom
Researchers used a deep-learning system to sift through a database of more than 40 million venom encrypted peptides (VEPs). In a matter of hours, the algorithm flagged 386 compounds with the molecular hallmarks of next-generation antibiotics.
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NewsEarly antibiotics alter immune function in infants- but a gut-derived molecule could help restore it
A new study has found that early-life exposure to antibiotics can impair an infant’s developing immune system, and that a naturally occurring metabolite may hold the key to reversing that damage.
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NewsFlightpath Biosciences licenses microbiome-sparing antibiotic developed at Illinois
Flightpath Biosciences, Inc., has licensed a class of antibiotics developed at the University of Illinois Urbana-Champaign. The original antibiotic agent, lolamicin, effectively treated bacterial infections in animal models of disease without wiping out beneficial gut microbes.
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NewsScientists target ‘molecular machine’ in the war against antimicrobial resistance
The ‘molecular machine’ flagellum is essential for bacteria to cause infection, allowing bacteria to ‘swim’ around the bloodstream until finding something to infect. But it could also be a target for antibiotics.
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NewsEvolutionary model for antibiotic resistance reveals dose timing critical to care
The study that uses a “fitness seascape” to incorporate a patient’s dosage schedule into models that predict whether an infection will develop antibiotic resistance has found that inconsistent timing and missing early doses can lead to treatment failure.
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NewsGlobal action urgently needed to tackle antimicrobial resistance, experts warn
Scientists have called for urgent changes to the way new antibiotics are developed to address the growing problem of antimicrobial resistance (AMR). They outline the scientific, economic, and regulatory barriers that are slowing progress.
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NewsGreen light activates this antibiotic only where it’s needed
To make a more efficient antibiotic treatment, researchers have modified penicillin so that it’s activated only by green light. In early tests, the approach precisely controlled bacterial growth and improved survival outcomes for infected insects.