All Antimicrobial Resistance articles – Page 10
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NewsSubstances isolated from marine sponges show potential for treating malária
In pre-clinical tests, compounds called batzelladins were found to be effective even against strains of Plasmodium that are resistant to conventional antimalarial drugs.
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NewsChameleon plant polysccharide targets acute pneumonia with H1N1 and MRSA coinfection
A new study discusses how an anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut–lung axis and NLRP3 inflammasome activation.
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NewsThirty years of research shows increased resistance in fungi
Fungi are increasingly resistant to antifungals, and the variation in resistance has significantly increased, reveals an analysis of more than 12,000 lung samples collected over thirty years in Dutch hospitals.
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NewsNew breakthrough uncovers how to kill ‘zombie’ TB cells resistant to antibiotics
Researchers exposed a library of over 500,000 genetically modified tuberculosis bacteria to two commonly used antibiotics. By analysing the survivors, they pinpointed genes whose disruption significantly reduced the number of surviving persisters.
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NewsMultiresistant intestinal bacteria: Displacement through food competition
Researchers made use of food competition to figure out how potentially dangerous multi-resistant bacteria could be effectively removed from the gut before reaching the bloodstream and causing serious problems.
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NewsScientists target ‘molecular machine’ in the war against antimicrobial resistance
The ‘molecular machine’ flagellum is essential for bacteria to cause infection, allowing bacteria to ‘swim’ around the bloodstream until finding something to infect. But it could also be a target for antibiotics.
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NewsAntibiotics are failing in many countries in Africa, new study reveals
The largest retrospective study on resistance to antibiotics in Africa highlights the need for major investments to enhance laboratory capabilities and healthcare access.
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NewsPrescribing fewer antibiotics might not be enough to combat threat of superbugs, says new research
Antimicrobial resistance is still spreading in the environment despite a reduction in the amounts of antibiotic drugs prescribed, according to a new study. Multiple approaches will be required to tackle the increasing threat of antimicrobial resistance to public health.
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NewsInternational comparison reveals gender differences in antimicrobial resistance
A recent study analysed the DNA map of more than 14,000 gut metagenomes in a global dataset and found differences in antibiotic resistance between genders. In high-income countries, women had more antibiotic resistance genes than men.
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NewsExcessive use of disinfectants in intensive care patients may increase the risk of antibiotic-resistant infections
An international study has, for the first time, revealed a strong and direct link between the rise of antibiotic-resistant bacteria and universal disinfection procedures applied to patients in intensive care units.
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NewsEvolutionary model for antibiotic resistance reveals dose timing critical to care
The study that uses a “fitness seascape” to incorporate a patient’s dosage schedule into models that predict whether an infection will develop antibiotic resistance has found that inconsistent timing and missing early doses can lead to treatment failure.
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NewsGlobal action urgently needed to tackle antimicrobial resistance, experts warn
Scientists have called for urgent changes to the way new antibiotics are developed to address the growing problem of antimicrobial resistance (AMR). They outline the scientific, economic, and regulatory barriers that are slowing progress.
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NewsScientists develop a treatment platform to disable the ‘biofilm’ shield of superbugs
Researchers have developed a platform that utilizes microbubbles to deliver gene-targeted nanoparticles capable of breaking down MRSA biofilms, offering an innovative solution for treating infections resistant to conventional antibiotics.
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NewsGifts from the sea: Molecules derived from coral may help fight harmful bacteria
Pus, strep throat, and even tuberculosis—most infectious diseases are characterized by a cluster of pathogenic bacteria that can be stubborn and resistant to antibiotics. Researchers have found another method to combat these bacteria using naturally sourced molecules found in corals.
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NewsA repurposed FDA-approved drug shows promise in killing antibiotic resistant bacteria
A study of Acinetobacter baumannii employed an entirely new strategy to identify weaknesses specific to resistant bacteria and then target these weaknesses with an alternate drug. They found that fendiline kills the bacterium by targeting the essential lipoprotein trafficking pathway, which is weakened in antibiotic resistant bacteria.
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NewsInfectious diseases experts raise alarm about antifungal resistance, call for global effort
Infectious disease experts are raising the alarm about the role new pesticides can play in building resistance to antifungal medical treatments, calling for a coordinated, global ”One Health” approach to developing, testing and using agents to fight pathogens.
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NewsNew study reveals global warming accelerates antibiotic resistance in soils
A new international study has revealed that climate change is accelerating the rate of development and global abundances of antibiotic resistance bacteria in soils.
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NewsResearch identifies new trigger accelerating antibiotic resistance
A new study shows that ciprofloxacin, a staple treatment for urinary tract infections, throws Escherichia coli (E. coli) into an energy crisis that saves many cells from death and speeds the evolution of full‑blown resistance.
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NewsNew source of natural antibiotics hidden within our own proteins identified
A team of scientists has identified a new type of antimicrobial peptides (AMPs) found in human proteins that are capable of selectively eliminating multidrug-resistant bacteria, particularly of the gram-negative type, responsible for serious hospital acquired infections.
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NewsCannabis extracts show remarkable effectiveness against fungal pathogens
Two cannabis-derived compounds have shown remarkable effectiveness against fungal pathogens in laboratory tests, according to new research.